Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Robert M. Caudle"'
Autor:
Basak Donertas-Ayaz, Robert M. Caudle
Publikováno v:
Neurobiology of Pain, Vol 13, Iss , Pp 100124- (2023)
Trigeminal neuralgia is the most common neuropathic pain involving the craniofacial region. Due to the complex pathophysiology, it is therapeutically difficult to manage. Noradrenaline plays an essential role in the modulation of arousal, attention,
Externí odkaz:
https://doaj.org/article/9fccc1b28133464db481dc15f2355014
Autor:
Robert M. Caudle, John K. Neubert
Publikováno v:
Frontiers in Pain Research, Vol 3 (2022)
The chemotherapeutic agent oxaliplatin is commonly used to treat colorectal cancer. Although effective as a chemotherapeutic, it frequently produces painful peripheral neuropathies. These neuropathies can be divided into an acute sensitivity to cool
Externí odkaz:
https://doaj.org/article/92a40131426d4cf994ce39c5ca369eb1
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/0e5cf137ee324a92983f73459946053b
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Rodent models of human disease can be valuable for understanding the mechanisms of a disease and for identifying novel therapies. However, it is critical that these models be vetted prior to committing resources to developing novel therapeutics. Fail
Externí odkaz:
https://doaj.org/article/eb4f6057fa354b729b0a00512380d340
Autor:
Adriaan W. Bruijnzeel, Azin Behnood-Rod, Wendi Malphurs, Ranjithkumar Chellian, Robert M. Caudle, Marcelo Febo, Barry Setlow, John K. Neubert
Publikováno v:
Behavioural Pharmacology. 33:418-426
The prescription opioid oxycodone is widely used for the treatment of pain in humans. Oxycodone misuse is more common among people with an anxiety disorder than those without one. Therefore, oxycodone might be misused for its anxiolytic properties. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d147c8c162b654e71da17f854b093b77
https://doi.org/10.1097/fbp.0000000000000690
https://doi.org/10.1097/fbp.0000000000000690
Autor:
Niall P. Murphy, Darrice S. Montgomery, Ariana C. Brice-Tutt, Cassidy M. Kramer, Peter M. Novotny, Wendi Malphurs, Robert M. Caudle, Adriaan W. Bruijnzeel, Abhisheak Sharma, Barry Setlow, John K. Neubert
Inter-relationships between pain sensitivity, drug reward, and drug misuse are of considerable interest given that many analgesics exhibit misuse potential. Here we studied rats as they underwent a series of pain- and reward-related tests: cutaneous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78a0dbab4b038365d0cb938bb9755add
https://doi.org/10.21203/rs.3.rs-2679319/v1
https://doi.org/10.21203/rs.3.rs-2679319/v1
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology
Frontiers in Pharmacology
Rodent models of human disease can be valuable for understanding the mechanisms of a disease and for identifying novel therapies. However, it is critical that these models be vetted prior to committing resources to developing novel therapeutics. Fail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41ce6f0f63d8c50e54e932fc5036eac7
https://www.frontiersin.org/articles/10.3389/fphar.2020.527495/full
https://www.frontiersin.org/articles/10.3389/fphar.2020.527495/full
Publikováno v:
Archives of Oral Biology. 92:18-24
Objective To assess changes in orofacial tactile sensitivity and gnawing related to capsaicin-mediated cutaneous, myogenic, and arthrogenic nociception in the rat. Design After recovery from anesthesia, orofacial tactile sensitivity and gnawing were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c3f288354d374f29a3da48d65730de
https://doi.org/10.1016/j.archoralbio.2018.04.013
https://doi.org/10.1016/j.archoralbio.2018.04.013
Autor:
Jason M. Keller, Stephen J. Raithel, Eric L. Rohrs, Andrew J. Mannes, Robert M. Caudle, Ethan M. Anderson, Dragan Maric, John A. Butman, Matthew R. Sapio, Dorothy Cimino Brown, Danielle M. LaPaglia, John K. Neubert, John D. Heiss, Michael J. Iadarola
Publikováno v:
Journal of Clinical Investigation. 128:1657-1670
Agonists of the vanilloid receptor transient vanilloid potential 1 (TRPV1) are emerging as highly efficacious nonopioid analgesics in preclinical studies. These drugs selectively lesion TRPV1+ primary sensory afferents, which are responsible for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77fdf786c3ddd595eae322ea1a8952ce
https://doi.org/10.1172/jci94331
https://doi.org/10.1172/jci94331
Autor:
Emily H. Lakes, Brittany Y. Jacobs, Heidi E. Kloefkorn, John K. Neubert, Eric L. Rohrs, Kyle D. Allen, Robert M. Caudle
Publikováno v:
Journal of Neuroscience Methods. 248:1-6
Detecting behaviors related to orofacial pain in rodent models often relies on subjective investigator grades or methods that place the animal in a stressful environment. In this study, an operant-based behavioral assay is presented for the assessmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee9e83aca0627377930b8c453f289498
https://doi.org/10.1016/j.jneumeth.2015.03.022
https://doi.org/10.1016/j.jneumeth.2015.03.022