Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Robert M. Breece"'
Publikováno v:
European Journal of Inorganic Chemistry. 2016:2641-2647
An examination of the solution spectroscopy of a series of tetrahedral bis-bispyrazolylborate complexes of CoII is presented. This includes a re-examination of the UV/Vis-NIR of the three stable derivatives, Bp2Co, Bp3,5Me2Co and (Ph2Bp)2Co, which sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::818c71518facc01e97b2dea39793f8aa
https://doi.org/10.1002/ejic.201501356
https://doi.org/10.1002/ejic.201501356
Autor:
M. Patrick Hensley, Robert M. Breece, Michael W. Crowder, Tara K. Sigdel, David L. Tierney, J. Allen Easton, Stacy A. Sugarbaker, Lindsey Klingbeil, Thusitha S. Gunasekera
Publikováno v:
Journal of Inorganic Biochemistry. 111:164-172
RT-PCR and DNA microarrays were used to probe for Zn(II)-responsive genes in E. coli cells that were made Zn(II) deficient. Microarray data revealed 114 genes were significantly up-regulated and 146 genes were significantly down-regulated in Zn(II) d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9ed38c959a3e924064b0b1a546f46c
https://doi.org/10.1016/j.jinorgbio.2011.11.022
https://doi.org/10.1016/j.jinorgbio.2011.11.022
Autor:
David L. Tierney, Faith E. Jacobsen, Tessa M. Woodruff, Seth M. Cohen, Shannon N. Oseback, Amy R. Marts, Sarah W. Shim, Robert M. Breece, Daniel R. Whitehead, Elizabeth T. Papish, Samuel M. Greer
Publikováno v:
Applied Magnetic Resonance. 40:501-511
The EPR spectra of high-spin Co(II) systems typically consist of poorly resolved resonances, broadened by a combination of large g-anisotropy, sizable spin–orbit couplings and admixture of excited state character into the magnetic ground state. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb9908dfd828d36b23341390a3a7d3d0
https://doi.org/10.1007/s00723-011-0225-5
https://doi.org/10.1007/s00723-011-0225-5
Autor:
Dae Won Cho, Debra Dunaway-Mariano, Patrick S. Mariano, Jiwen Zou, David L. Tierney, Maozhen Gong, Zhengang Liu, Zhimin Li, Robert M. Breece, Gabriel D. Maestas, Osnat Herzberg, Andrey Galkin, Ling Li, Hong Zhao
Publikováno v:
Journal of Inorganic Biochemistry. 105:509-517
Inhibitors of the Giardia lamblia fructose 1,6-bisphosphate aldolase (GlFBPA), which transforms fructose 1,6-bisphosphate (FBP) to dihydroxyacetone phosphate and glyceraldehyde 3-phosphate, were designed based on 3-hydroxy-2-pyridone and 1,2-dihydrox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b2c261ab4d68190f21d14f8aaef5f9
https://doi.org/10.1016/j.jinorgbio.2010.12.012
https://doi.org/10.1016/j.jinorgbio.2010.12.012
Autor:
Katherine M. Bender, Michael W. Crowder, Brian Bennett, Christine E. Hajdin, David L. Tierney, Alison L. Costello, Zhenxin Hu, Megan J. Hawk, Robert M. Breece
Publikováno v:
Journal of the American Chemical Society. 131:10753-10762
In an effort to probe the structure, mechanism, and biochemical properties of metallo-beta-lactamase Bla2 from Bacillus anthracis, the enzyme was overexpressed, purified, and characterized. Metal analyses demonstrated that recombinant Bla2 tightly bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb9b966c983048b44bc6892e55e9ff1
https://doi.org/10.1021/ja900296u
https://doi.org/10.1021/ja900296u
Publikováno v:
Journal of the American Chemical Society. 129:12815-12827
Zinc finger transcription factors represent the largest single class of metalloproteins in the human genome. Binding of Zn(II) to their canonical Cys4, Cys3His1, or Cys2His2 sites results in metal-induced protein folding events required to achieve th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d743210f58438a45df19dfb5e1091f57
https://doi.org/10.1021/ja073902+
https://doi.org/10.1021/ja073902+
Autor:
Catalina Achim, Raphael M. Franzini, David L. Tierney, Goutam K. Patra, Robert M. Breece, Richard M. Watson, Michael P. Hendrich
Publikováno v:
Inorganic Chemistry. 45:9798-9811
Substitution of natural nucleobases in PNA oligomers with ligands is a strategy for directing metal ion incorporation to specific locations within a PNA duplex. In this study, we have synthesized PNA oligomers that contain up to three adjacent bipyri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6d23f3808da0825508e0c196d0e6fb
https://doi.org/10.1021/ic0609610
https://doi.org/10.1021/ic0609610
Publikováno v:
Biochemistry. 45:13385-13393
Lactone-hydrolyzing enzymes derived from some Bacillus species are capable of disrupting quorum sensing in bacteria that use N-acyl-l-homoserine lactones (AHLs) as intercellular signaling molecules. Despite the promise of these quorum-quenching enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7314c45c7fca13ebacb81887a8014adf
https://doi.org/10.1021/bi061238o
https://doi.org/10.1021/bi061238o
Publikováno v:
Inorganic Chemistry. 45:7306-7315
The tetrahedral cobalt(II) complex [(Tp(Ph,Me))CoCl] (Tp(Ph,Me) = hydrotris(3,5-phenylmethylpyrazolyl)borate) was combined with several hydroxypyridinone, hydroxypyridinethione, pyrone, and thiopyrone ligands to form the corresponding [(Tp(Ph,Me))Co(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45146ef52428d73d9439b0385f392d98
https://doi.org/10.1021/ic060901u
https://doi.org/10.1021/ic060901u
Autor:
Timothy K. Richmond, Dionne H. Griffin, Michael W. Crowder, David L. Tierney, Abraham Jon Moller, Carlo Sanchez, Robert M. Breece, Brian Bennett
Publikováno v:
Biochemistry. 50(42)
In an effort to probe for metal binding to metallo-β-lactamase (MβL) IMP-1, the enzyme was overexpressed, purified, and characterized. The resulting enzyme was shown to bind 2 equiv of Zn(II), exhibit significant catalytic activity, and yield EXAFS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f902f3cab0079e73e6de03e3b825f6e3
https://pubmed.ncbi.nlm.nih.gov/21928807
https://pubmed.ncbi.nlm.nih.gov/21928807