Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Robert M W, de Waal"'
Autor:
Elisanne A L M, Biemans, Lieke, Jäkel, Robert M W, de Waal, H Bea, Kuiperij, Marcel M, Verbeek
Publikováno v:
Journal of Neuroscience Research
Alzheimer's disease and cerebral amyloid angiopathy are characterized by accumulation of amyloid‐β (Aβ) at the cerebrovasculature due to decreased clearance at the blood‐brain barrier (BBB). However, the exact mechanism of Aβ clearance across
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5a6ace8272573b797acd38c288f9544
https://pubmed.ncbi.nlm.nih.gov/27726164
https://pubmed.ncbi.nlm.nih.gov/27726164
Autor:
Robert M. W. de Waal
Publikováno v:
Molecular Biology Reports. 19:81-88
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e69e3267ed7916ee3b992cc5fced65
https://doi.org/10.1007/bf00997151
https://doi.org/10.1007/bf00997151
Autor:
Ilona B, Bruinsma, Kim A, Bruggink, Karsten, Kinast, Alexandra A M, Versleijen, Ine M J, Segers-Nolten, Vinod, Subramaniam, H Bea, Kuiperij, Wilbert, Boelens, Robert M W, de Waal, Marcel M, Verbeek
Publikováno v:
Proteins. 79(10)
The fibrillization of α-synuclein (α-syn) is a key event in the pathogenesis of α-synucleinopathies. Mutant α-syn (A53T, A30P, or E46K), each linked to familial Parkinson's disease, has altered aggregation properties, fibril morphologies, and fib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9650591a5c7f4ccd8663829c8116d87
https://pubmed.ncbi.nlm.nih.gov/21905118
https://pubmed.ncbi.nlm.nih.gov/21905118
Autor:
Hannie C.M. Robben, Robert A.P. Koene, M. José J.T. Bogman, Hans van Gasteren, Karel J.M. Assmann, Robert M. W. de Waal, Gideon Schrijver
Publikováno v:
Kidney International. 38(1):86-95
Anti-GBM nephritis in the mouse: Role of granulocytes in the heterologous phase. The role of polymorphonuclear granulocytes (PMNs) was studied in a model of anti-GBM nephritis in mice, in which PMN depletion was induced by total body irradiation of 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d5418e57c27f66fb0cc10a8afdad07
Autor:
Benno, Küsters, Robert M W, de Waal, Pieter, Wesseling, Kiek, Verrijp, Cathy, Maass, Arend, Heerschap, Jelle O, Barentsz, Fred, Sweep, Dirk J, Ruiter, William P J, Leenders
Publikováno v:
Cancer research. 63(17)
We reported previously that vascular endothelial growth factor isoform A (VEGF-A) expression by Mel57 human melanoma cells led to tumor progression in a murine brain metastasis model in an angiogenesis-independent fashion by dilation of co-opted, pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9582de768c4d19d249d85fe9db094bc4
https://pubmed.ncbi.nlm.nih.gov/14500375
https://pubmed.ncbi.nlm.nih.gov/14500375
Autor:
William, Leenders, Benno, Küsters, Jeroen, Pikkemaat, Pieter, Wesseling, Dirk, Ruiter, Arend, Heerschap, Jelle, Barentsz, Robert M W, de Waal
Publikováno v:
International journal of cancer. 105(4)
We have previously shown that the dense vascular network in mouse brain allows for growth of human melanoma xenografts (Mel57) by co-option of preexisting vessels. Overexpression of recombinant vascular endothelial growth factor-A (VEGF-A) by such xe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04ea32496c887093b2e8f92bf8806348
https://pubmed.ncbi.nlm.nih.gov/12712432
https://pubmed.ncbi.nlm.nih.gov/12712432
Publikováno v:
Cancer research. 62(23)
The anatomical relation between a malignant tumor and its vascular and lymphatic bed is an important factor influencing metastasis. Lack of specific markers for the lymphatic endothelium has long hampered a reliable detection of lymphatics. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::439a018d3e8272bfe640843fbbafe828
https://pubmed.ncbi.nlm.nih.gov/12460927
https://pubmed.ncbi.nlm.nih.gov/12460927
Publikováno v:
Investigative ophthalmologyvisual science. 43(4)
Recently, it was reported that tumor cells themselves generate channels and networks in three-dimensional culture and can be found lining channels (some containing red blood cells [RBCs]) in vivo, and they express endothelial or vascular genes in agg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b786f5a2cd304b4061d45ba88d7b2f9
https://pubmed.ncbi.nlm.nih.gov/11923228
https://pubmed.ncbi.nlm.nih.gov/11923228
Autor:
Benno, Küsters, William P J, Leenders, Pieter, Wesseling, Debby, Smits, Kiek, Verrijp, Dirk J, Ruiter, Johannes P W, Peters, Albert J, van Der Kogel, Robert M W, de Waal
Publikováno v:
Cancer research. 62(2)
We investigated the mechanisms of vascularization in a brain metastases model of malignant melanoma. Parenchymal metastases expressing little vascular endothelial growth factor-A (VEGF-A) co-opted the preexistent brain vasculature, leading to an infi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9dc86e529a2abfe283f047551340e782
https://pubmed.ncbi.nlm.nih.gov/11809675
https://pubmed.ncbi.nlm.nih.gov/11809675
Publikováno v:
Cerebral Amyloid Angiopathy in Alzheimer’s Disease and Related Disorders ISBN: 9789048154807
Like senile plaques, cerebral amyloid angiopathy (CAA) does not result from accumulation of the amyloid β(Aβ) protein alone, but also contains a number of other components, referred to as amyloid β-associated proteins. In this review we will discu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab56bd68a52d597d903aa038f9eeeaa0
https://doi.org/10.1007/978-94-017-1007-7_12
https://doi.org/10.1007/978-94-017-1007-7_12
