Zobrazeno 1 - 10
of 211
pro vyhledávání: '"Robert M Senior"'
Autor:
Tracy L Adair-Kirk, Gail L Griffin, Michelle J Meyer, Diane G Kelley, Jeffrey H Miner, Douglas R Keene, M Peter Marinkovich, J Michael Ruppert, Jouni Uitto, Robert M Senior
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45546 (2012)
Laminin-332 is a heterotrimeric basement membrane component comprised of the α3, ß3, and γ2 laminin chains. Laminin-332 modulates epithelial cell processes, such as adhesion, migration, and differentiation and is prominent in many embryonic and ad
Externí odkaz:
https://doaj.org/article/0d0b7f25a524459b96d7840d807b0f76
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41348 (2012)
The labyrinth is the highly vascularized part of the rodent placenta that allows efficient transfer of gases, nutrients, wastes, and other molecules between the maternal and embryonic circulations. These two blood compartments are separated by blasto
Externí odkaz:
https://doaj.org/article/3fc29e9512e44d688cbcc5388a3e05de
Autor:
Taylor Adams, Buqu Hu, Scott M. O'Neal, Tony Woolard, Panagiotis V. Benos, Michael J. Becich, Yingze Zhang, David R. Moller, Erica L. Herzog, Joseph K. Leader, Robert M. Senior, Mridu Gulati, Hubertus D. Luijk, Nachelle Aurelien, Laura L. Koth, Alison Morris, Harry Hochheiser, Xiting Yan, Naftali Kaminski, Stephen R. Wisniewski, Kevin F. Gibson, Wenlan Zang, Giuseppe DeIuliis, Joe G. N. Garcia, Antun Mihaljinec, Wonder P. Drake, Milica Vukmirovic, Lisa A. Maier, Edward S. Chen
Publikováno v:
Molecular Pathology and Functional Genomics.
Introduction: We analyzed the transcriptome of bronchoalveolar lavage cells (BAL) in a large cohort of well characterized sarcoidosis subjects by RNA-sequencing to better understand disease progression and severity, and potentially identify novel mol
Autor:
Tetsu Kobayashi, Jeffrey J. Atkinson, Fu Qiang Wen, Robert M. Senior, Shinji Abe, Qiuhong Fang, Tadashi Kohyama, Xiangde Liu, James M. Shipley, Hui Jung Kim, Stephen I. Rennard, Xingqi Wang, Hisatoshi Sugiura
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 306:L1006-L1015
Matrix metalloproteinase-9 (MMP-9) is a matrix-degrading enzyme implicated in many biological processes, including inflammation. It is produced by many cells, including fibroblasts. When cultured in three-dimensional (3D) collagen gels, fibroblasts c
Autor:
Fernando D. Martinez, Sandra Colombini-Hatch, Yvonne J. Huang, Ronald G. Collman, Emily S. Charlson, Robert M. Senior
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
Study of the human lung microbiome in the context of pulmonary health and disease is an area of emerging research interest that is being driven by several contributing factors. These factors include increased recognition of the diversity of human-ass
Autor:
Michael A. Grippi, Jack A. Elias, Jay A. Fishman, Allan I. Pack, Robert M. Senior, Robert Kotloff
Turn to the field's definitive text for a thorough understanding of the clinical and scientific aspects of pulmonary medicine Since 1980, Fishman's Pulmonary Diseases and Disorders has delivered unparalleled coverage of pulmonary medicine and the und
Autor:
Antonio Nanci, Robert M. Senior, Luiz C. Viegas-Costa, Aurélien Fouillen, Pierre Moffatt, Tracy L. Adair-Kirk, Rima Wazen
Publikováno v:
Matrix biology : journal of the International Society for Matrix Biology.
The epithelial ameloblasts are separated from the maturing enamel by an atypical basement membrane (BM) that is enriched in laminin 332 (LM-332). This heterotrimeric protein (α3, s3 and γ2 chains) provides structural integrity to BMs and influences
Autor:
Susan H. Conradi, Diane G. Kelley, Yoko Suzuki, Gaëtan Deslée, Jeffrey J. Atkinson, Carla Moore, Dale K. Kobayashi, Whitney G. Ijem, Richard A. Pierce, Barbara A. Lutey, Tomoko Betsuyaku, David S. Gierada, M. Eileen Jacobs, Holly M. Toennies, Robert M. Senior
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 183:876-884
Matrix metalloprotease (MMP)-9 is an elastolytic endopeptidase produced by activated macrophages that may be involved in the development of human pulmonary emphysema and could be inhibited with existing compounds. Mouse models have demonstrated that
Autor:
David S. Gierada, Barbara A. Lutey, Jeffrey J. Atkinson, Robert M. Senior, Susan H. Conradi, Wei Wang
Publikováno v:
Academic Radiology. 17:1525-1534
Rationale and Objectives Airway wall dimensions can be determined in vivo using transverse computed tomographic (CT) images, but the measurement of airway phantoms shows that the wall thickness is consistently overestimated for small airways. This ph
Autor:
Yoshio Matsui, Hideki Amano, Hidero Kitasato, Masataka Majima, Shuh Narumiya, Takahiko Murata, Yoshiya Ito, Tastunori Suzuki, Robert M. Senior, Shintaro Kato, Yukitoshi Satoh, Izumi Hayashi, Yukihiko Sugimoto, Fumihiro Ogawa
Publikováno v:
Cancer Science. 100:2318-2324
Cyclooxygenase (COX)-2 is known to correlate with poor cancer prognosis and to contribute to tumor metastasis. However, the precise mechanism of this phenomenon remains unknown. We have previously reported that host stromal prostaglandin E(2) (PGE(2)