Zobrazeno 1 - 10
of 337
pro vyhledávání: '"Robert M Nelson"'
Autor:
Christina Bucci-Rechtweg, Angeliki Siapkara, Kristina An Haack Bonnet, Solange Corriol Rohou, Elin Haf Davies, Martine Dehlinger Kremer, Margaret Gamalo, Carmen Moreno, Robert M Nelson, Rhian Thomas Turner
Publikováno v:
Clinical Trials. 20:13-21
Background: Historically, pediatric medicines are developed after adult trials are completed, even when identical drug targets and disease similarities exist across the populations. This has resulted in significant delays in the authorization of medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::269c4fe54475265e57b18d1fec0eb398
https://doi.org/10.1177/17407745221132302
https://doi.org/10.1177/17407745221132302
Autor:
Jocelyn H. Leu, Natalie J. Shiff, Michael Clark, Karen Bensley, Kathleen G. Lomax, Katherine Berezny, Robert M. Nelson, Honghui Zhou, Zhenhua Xu
Publikováno v:
Pediatric Drugs. 24:699-714
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e68c419a97e59e2e31788f2789730983
https://doi.org/10.1007/s40272-022-00533-y
https://doi.org/10.1007/s40272-022-00533-y
Autor:
Robert M. Nelson, Laurie S. Conklin, Wendy J. Komocsar, Fei Chen, Forrest Williamson, Wallace V. Crandall
Publikováno v:
Therapeutic Innovation & Regulatory Science. 56:895-902
Master protocols are innovative clinical trial designs that enable new approaches to analytics and operations, creating value for patients and drug developers. To date, the use of master protocols in pediatric drug development has been limited, focus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93535fd8b16969974fab11846d0be4e6
https://doi.org/10.1007/s43441-022-00448-3
https://doi.org/10.1007/s43441-022-00448-3
Autor:
Laura E. Schanberg, Lily (Yeruk) Mulugeta, Bolanle Akinlade, Hermine I. Brunner, Jianmeng Chen, Robert A. Colbert, Vincent Delgaizo, Marc R. Gastonguay, Rachel Glaser, Lisa Imundo, Daniel J. Lovell, Jocelyn H. Leu, Nael M. Mostafa, Robert M. Nelson, Peter A. Nigrovic, Nikolay P. Nikolov, Lisa G. Rider, Rebecca Rothwell, Chandrahas Sahajwalla, Renu Singh, Vikram Sinha, Carolyn L. Yancey, Lynne Yao
Publikováno v:
Arthritis & Rheumatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42ccce1811effae897137b13f08f7027
https://doi.org/10.1002/art.42534
https://doi.org/10.1002/art.42534
Autor:
Donna Griebel, Insook Kim, Robert M. Nelson, Jeremiah D. Momper, M. Tobias Heinrichs, Issam Zineh, Yeruk Mulugeta, Nitin Mehrotra, Shaun Kumar, Gregory H. Reaman, Vikram Sinha, Hari Cheryl Sachs, Narayana Garimella, Gilbert J. Burckart, Lynne Yao, Kevin Krudys, Andrew E. Mulberg
Publikováno v:
The Journal of Clinical Pharmacology. 60:775-784
Chemotherapy-induced nausea and vomiting (CINV) is a common treatment-related adverse event that negatively impacts the quality of life of cancer patients. During pediatric drug development, extrapolation of efficacy from adult to pediatric populatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ecc62c7baa425edbca6a89cf6b56d5f
https://doi.org/10.1002/jcph.1577
https://doi.org/10.1002/jcph.1577
Autor:
Margaret Gamalo, Christina Bucci-Rechtweg, Robert M. Nelson, Linh Vanh, Ariel Porcalla, Helen Thackray, Freda Cooner, Lauren Cutler, Danielle Friend, Ron Portman
Publikováno v:
Therapeutic innovationregulatory science. 56(6)
Pediatric drug development lags adult development by about 8 years (Mulugeta et al. in Pediatr Clin 64(6):1185-1196, 2017). In such context, many incentives, regulations, and innovative techniques have been proposed to address the disparity for pedia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c808e31e01c11890373f3ced8d3ae1e
https://pubmed.ncbi.nlm.nih.gov/35006587
https://pubmed.ncbi.nlm.nih.gov/35006587
Autor:
Robert M. Nelson
Publikováno v:
The American Journal of Bioethics. 20:114-116
The proposed clinical trial (Johnson et al. 2020) of low dose interleukin 2 (IL-2) for the treatment of adolescents with systemic lupus erythematosus (SLE) should be evaluated from two perspectives...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f675751a4e779713411ead3ec130846a
https://doi.org/10.1080/15265161.2020.1730489
https://doi.org/10.1080/15265161.2020.1730489
Autor:
Ronald J. Portman, Sebastian Weber, Kattayoun Kordy, Robert M. Nelson, Margaret Gamalo-Siebers, Lisa V. Hampson
Publikováno v:
Therapeutic Innovation & Regulatory Science. 53:567-578
The conduct of pediatric clinical trials is legally required, monitored, and encouraged in major geographic areas such as the United States and Europe. However, because pediatric patients are considered vulnerable populations, they should only be enr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d275bc861686389645a3a53dada07f5
https://doi.org/10.1177/2168479019842541
https://doi.org/10.1177/2168479019842541
Autor:
Thomas E. Taylor, Brendan Fisher, Robert M. Nelson, Michael R. Gunson, Christopher W. O'Dell, Greg Osterman, Kivi Rigel, Akihiko Kuze, David W. T. Griffith, Hannakaisa Lindqvist, David Crisp, Annmarie Eldering, Vivienne H. Payne, Debra Wunch
The GOSAT TANSO-FTS sensor has been collecting high spectral resolution measurements of reflected solar radiation in the Oxygen A-band (0.76 microns) and two shortwave-infrared carbon dioxide (CO2) absorption bands (1.6 and 2.0 microns) since April,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb216abcb675373bcca0fca1a518e50d
https://doi.org/10.5194/egusphere-egu21-10193
https://doi.org/10.5194/egusphere-egu21-10193
Autor:
Robert M. Nelson, Benjamin D. Braaten
Publikováno v:
2007 North Midwest Section Meeting Proceedings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b83d5b5be663ff09dfb2bbc2c41a3afc
https://doi.org/10.18260/1-2-1115-36186
https://doi.org/10.18260/1-2-1115-36186