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pro vyhledávání: '"Robert M, Weis"'
Geobacter sulfurreducens , an anaerobic metal-reducing bacterium, possesses type IV pili. These pili are intrinsic structural elements in biofilm formation and, together with a number of c -type cytochromes, are thought to serve as conductive nanowir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb24fe78e9a0302bed8deff3c536cb5
https://europepmc.org/articles/PMC5370424/
https://europepmc.org/articles/PMC5370424/
Autor:
Lynmarie K. Thompson, Meili Yang, Aruni P. K. K. Karunanayake Mudiyanselage, Robert M. Weis, Lee A.-R. Accomando
Publikováno v:
Biochemistry. 52:6127-6136
Many cellular processes involve interactions between membrane-associated proteins, and those interactions are enhanced by membrane association. We have used cross-linking reactions to compare the extent and specificity of protein interactions in solu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088307b57429f2a2a0657624cf5c6b34
https://doi.org/10.1021/bi4007176
https://doi.org/10.1021/bi4007176
Autor:
Anthony D. Dinsmore, Aruni P. K. K. Karunanayake Mudiyanselage, Robert M. Weis, Jaime Hutchison
Publikováno v:
Soft matter. 12(8)
The binding affinity of a curvature-sensing protein domain (N-BAR) is measured as a function of applied osmotic stress while the membrane curvature is nearly constant. Varying the osmotic stress allows us to control membrane tension, which provides a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a00cc5ac9bdc11dc38cca67969871ea
https://pubmed.ncbi.nlm.nih.gov/26822233
https://pubmed.ncbi.nlm.nih.gov/26822233
Autor:
Frances M, Antommattei, Robert M, Weis
Publikováno v:
The Enzymes. 24
The methyltransferase CheR catalyzes methyl group transfer from S-adenosyl-l-methionine to specific glutamic acid side chains of bacterial chemoreceptors, referred to as the methyl-accepting chemotaxis proteins (MCPs). A second enzyme, the methyleste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b28ad574925b0734f405fff969362a7
https://pubmed.ncbi.nlm.nih.gov/26718046
https://pubmed.ncbi.nlm.nih.gov/26718046
Publikováno v:
Biochemistry. 51:6920-6931
Two-component signaling pathways, a signal transduction motif that is widespread in prokaryotes and found in some eukaryotes, involve the autophosphorylation of histidine kinases and phosphotransfer to aspartyl groups of response regulators (1). Bact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a550690d01212e7f0976bcac056f5527
https://doi.org/10.1021/bi3007466
https://doi.org/10.1021/bi3007466
Publikováno v:
Journal of Bacteriology. 194:2551-2563
Type IV pili of Geobacter sulfurreducens are composed of PilA monomers and are essential for long-range extracellular electron transfer to insoluble Fe(III) oxides and graphite anodes. A previous analysis of pilA expression indicated that transcripti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6482588804beca2e34e32d6be80a62a
https://doi.org/10.1128/jb.06366-11
https://doi.org/10.1128/jb.06366-11
Autor:
Boguslaw Stec, Robert M. Weis, Kimberly A. Stieglitz, Zheng Li, Mary F. Roberts, Yang Wei, Anthony L. Shrout
Publikováno v:
Protein Science. 19:309-318
The inositol monophosphatase (IMPase) enzyme from the hyperthermophilic archaeon Methanocaldococcus jannaschii requires Mg(2+) for activity and binds three to four ions tightly in the absence of ligands: K(D) = 0.8 muM for one ion with a K(D) of 38 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33cf2fd9cc5e3860482952e38597b4e9
https://doi.org/10.1002/pro.315
https://doi.org/10.1002/pro.315
Publikováno v:
Biochemistry. 49:1425-1434
The receptor dimers that mediate bacterial chemotaxis form high-order signaling complexes with CheW and the kinase CheA. From the packing arrangement in two crystal structures of different receptor cytoplasmic fragments, two different models have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8bb29935142d047c0ab1f125248056
https://doi.org/10.1021/bi901565k
https://doi.org/10.1021/bi901565k
Publikováno v:
SLAS Discovery. 13:810-816
Receptor tyrosine kinases have become important therapeutic targets because of their involvement in diseases, including cancer. Kinase domains, which are soluble and easily purified, have found widespread use in enzyme inhibitor assays, but these dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0025a8cd6b11f0ad8e3aa14889fb89ef
https://doi.org/10.1177/1087057108322062
https://doi.org/10.1177/1087057108322062
Publikováno v:
Chemical Biology & Drug Design. 71:278-281
A multitude of proteins reside at or near the cell membrane, which provides a unique environment for organizing and promoting assemblies of proteins that are involved in a variety of cellular signaling functions. Many of these proteins and pathways a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac67fb431c87a7b2d30537efeab2ba81
https://doi.org/10.1111/j.1747-0285.2008.00627.x
https://doi.org/10.1111/j.1747-0285.2008.00627.x