Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Robert M, Sears"'
Autor:
Cynthia Bleiwas, Cátia M. Teixeira, Robert M. Sears, Stefanie Canals-Baker, John F. Smiley, Mariko Saito, Donald A. Wilson, Sharifa Z. Williams
Publikováno v:
Alcohol
In animal models that mimic human third-trimester fetal development, ethanol causes substantial cellular apoptosis in the brain, but for most brain structures, the extent of permanent neuron loss that persists into adulthood is unknown. We injected e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe2c454cf988f187e20e10e3fc375d0
https://doi.org/10.1016/j.alcohol.2021.08.005
https://doi.org/10.1016/j.alcohol.2021.08.005
Autor:
Robert M. Sears, Danielle M. Moloney, Christopher K. Cain, Shanna B. Samels, Lindsay C. Laughlin
Publikováno v:
Learn Mem
In the signaled active avoidance (SigAA) paradigm, rats learn to suppress Pavlovian reactions (e.g. freezing) and emit instrumental actions (e.g. shuttling) to escape threats and prevent pain. This paradigm is critical for understanding aversively-mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b943b27285cf9d53a4181ddea958cc8
Autor:
Jon Brudvig, H. T. Ghashghaei, G. G. Schmidt-Grimminger, Kenneth B. Adler, Jill M. Weimer, Robert M. Sears, Jacob T. Cain, Erika S. Wittchen
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
Through the process of neuronal differentiation, newly born neurons change from simple, spherical cells to complex, sprawling cells with many highly branched processes. One of the first stages in this process is neurite initiation, wherein cytoskelet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0123914f91496d4cc99e2e7ae75b0559
http://link.springer.com/article/10.1038/s41598-018-31578-0
http://link.springer.com/article/10.1038/s41598-018-31578-0
Autor:
Joram D Mul, Susanne E la Fleur, Pim W Toonen, Anthonieke Afrasiab-Middelman, Rob Binnekade, Dustin Schetters, Michel M M Verheij, Robert M Sears, Judith R Homberg, Anton N M Schoffelmeer, Roger A H Adan, Ralph J DiLeone, Taco J De Vries, Edwin Cuppen
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19600 (2011)
Current epidemic obesity levels apply great medical and financial pressure to the strenuous economy of obesity-prone cultures, and neuropeptides involved in body weight regulation are regarded as attractive targets for a possible treatment of obesity
Externí odkaz:
https://doaj.org/article/856a88d2de5d49c7b8dbdde7f3492dfd
Autor:
Richard Trinko, Geliang Gan, Xiao-Bing Gao, Robert M Sears, Douglas J Guarnieri, Ralph J DiLeone
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27180 (2011)
Leptin acts on the ventral tegmental area (VTA) to modulate neuronal function and feeding behavior in rats and mice. To identify the intracellular effectors of the leptin receptor (Lepr), downstream signal transduction events were assessed for regula
Externí odkaz:
https://doaj.org/article/a9b0b9f4e7c645de9baa7fb3dd6a4696
Autor:
Robert M. Sears, Adriana Heguy, Eric Klann, Zachary Deane, Rahul N. Kanadia, Aristotelis Tsirigos, Joseph E. LeDoux, Tenzin Lhakhang, Linnaea E. Ostroff, Emanuela Santini
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
Local translation can support memory consolidation by supplying new proteins to synapses undergoing plasticity. Translation in adult forebrain dendrites is an established mechanism of synaptic plasticity and is regulated by learning, yet there is no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f601009c6b7efd93ceb1461521255e
https://doi.org/10.7554/elife.51607
https://doi.org/10.7554/elife.51607
Autor:
Robert M. Sears, Tenzin Lhakhang, Linnaea E. Ostroff, Adriana Heguy, Rahul N. Kanadia, Aristotelis Tsirigos, Joseph E. LeDoux, Eric Klann, Zachary Deane, Emanuela Santini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8bf4fe6d734909a894f868b7d45c241
https://doi.org/10.7554/elife.51607.sa2
https://doi.org/10.7554/elife.51607.sa2
Autor:
Robert M. Sears, Gary Aston-Jones, Walter T. Piper, Longnian Lin, Elena M. Vazey, Yiran Gu, Lauren A. Branigan, Joseph E. LeDoux
Publikováno v:
Molecular Psychiatry
Norepinephrine (NE) plays a central role in the acquisition of aversive learning via actions in the lateral nucleus of the amygdala (LA) [1, 2]. However, the function of NE in expression of aversively-conditioned responses has not been established. G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3cd56241ad8e90500db3788d3f3e49
https://pubmed.ncbi.nlm.nih.gov/31758092
https://pubmed.ncbi.nlm.nih.gov/31758092
Norepinephrine (NE) plays a central role in the acquisition of aversive learning via actions in the lateral nucleus of the amygdala (LA)1,2. However, the function of NE in expression of aversively-conditioned responses has not been established. Given
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a77e3c42cc06b8e0fa6d3fa84398a2a
https://doi.org/10.1101/519249
https://doi.org/10.1101/519249