The PANDORA Study: Prevalence and Outcome of Acute Hypoxemic Respiratory Failure in the Pre-COVID-19 Era

Autor: Jesús Villar, MD, PhD, FCCM, Juan M. Mora-Ordoñez, MD, Juan A. Soler, MD, PhD, Fernando Mosteiro, MD, PhD, Anxela Vidal, MD, Alfonso Ambrós, MD, PhD, Lorena Fernández, MD, Isabel Murcia, MD, Belén Civantos, MD, Miguel A. Romera, MD, Adrián Mira, MD, Francisco J. Díaz-Domínguez, MD, Dácil Parrilla, MD, J. Francisco Martínez-Carmona, MD, Domingo Martínez, MD, Lidia Pita-García, MD, Denis Robaglia, MD, Ana Bueno-González, MD, Jesús Sánchez-Ballesteros, MD, Ángel E. Pereyra, MD, Mónica Hernández, MD, Carlos Chamorro-Jambrina, MD, Pilar Cobeta, MD, Raúl I. González-Luengo, MD, Raquel Montiel, MD, Leonor Nogales, MD, M. Mar Fernández, MD, PhD, Blanca Arocas, MD, Álvaro Valverde-Montoro, MD, Ana M. del Saz-Ortiz, MD, Victoria Olea-Jiménez, MD, José M. Añón, MD, PhD, Pedro Rodríguez-Suárez, MD, Rosa L. Fernández, MSc, Cristina Fernández, MSc, Tamas Szakmany, MD, PhD, Jesús M. González-Martín, PhD, Carlos Ferrando, MD, PhD, Robert M. Kacmarek, PhD, RTT, Arthur S. Slutsky, MD, for the Prevalence AND Outcome of acute hypoxemic Respiratory fAilure (PANDORA) Network, José M. Añón, Belén Civantos, Mónica Hernández, Elena González, Rosario Solano, F. Javier Díaz-Domínguez, Demetrio Carriedo, Raul I. González Luengo, Carlos Ferrando, Blanca Arocas, Javier Belda, Marina Soro, Gerardo Aguilar, Ernesto Pastor, Lorena Fernández, Jesús Sánchez-Ballesteros, Arturo Muriel, Pablo Blanco-Schweizer, José Ángel de Ayala, Jesús Blanco, César Aldecoa, Alba Pérez, Jesús Rico-Feijoo, Leonor Nogales, David Andaluz, Laura Parra, Juan A. Soler, Domingo Martínez, Ana M. del Saz-Ortiz, Alfonso Ambrós, Ana Bueno-González, Carmen Hornos-López, Raquel Montiel, Dácil Parrilla, Eduardo Peinado, Isidro Prieto, Mario Chico, Miguel A. Romera, Carlos Chamorro-Jambrina, Juan M. Mora-Ordoñez, J. Francisco Martínez-Carmona, Álvaro Valverde-Montoro, Victoria Olea-Jiménez, Paco Alba, Ruth Corpas, Fernando Mosteiro, Lidia Pita-García, Eleuterio Merayo, Chanel Martínez, Ángeles de Célis-Álvarez, Carmen Martín-Delgado, Adrián Mira, Pilar Cobeta, David Pestaña, María del Mar Fernández, Concepción Tarancón, Silvia Cortés-Díaz, Anxela Vidal, Denis Robaglia, César Pérez, Isabel Murcia, Ángel E. Pereyra-Pache, Tamas Szakmany, Jesús Villar, Rosa L. Fernández, Cristina Fernández, Pedro Rodríguez-Pérez, Jesús M. González-Martín, Robert M. Kacmarek, Arthur S. Slutsky

Publikováno v: Critical Care Explorations, Vol 4, Iss 5, p e0684 (2022)

OBJECTIVES:. To establish the epidemiological characteristics, ventilator management, and outcomes in patients with acute hypoxemic respiratory failure (AHRF), with or without acute respiratory distress syndrome (ARDS), in the era of lung-protective

Externí odkaz: https://doaj.org/article/b683f9f5f7364cd08c59c3940ccadbd0

A lung rescue team improves survival in obesity with acute respiratory distress syndrome

Autor: Gaetano Florio, Matteo Ferrari, Edward A. Bittner, Roberta De Santis Santiago, Massimiliano Pirrone, Jacopo Fumagalli, Maddalena Teggia Droghi, Cristina Mietto, Riccardo Pinciroli, Sheri Berg, Aranya Bagchi, Kenneth Shelton, Alexander Kuo, Yvonne Lai, Abraham Sonny, Peggy Lai, Kathryn Hibbert, Jean Kwo, Richard M. Pino, Jeanine Wiener-Kronish, Marcelo B. P. Amato, Pankaj Arora, Robert M. Kacmarek, Lorenzo Berra, For the investigators of the lung rescue team

Publikováno v: Critical Care, Vol 24, Iss 1, Pp 1-11 (2020)

Abstract Background Limited data exist regarding ventilation in patients with class III obesity [body mass index (BMI) > 40 kg/m2] and acute respiratory distress syndrome (ARDS). The aim of the present study was to determine whether an individualized

Externí odkaz: https://doaj.org/article/227969ed632346cb953b9e2c67ba6846

Systemic Effects Induced by Hyperoxia in a Preclinical Model of Intra-abdominal Sepsis

Autor: M. Isabel García-Laorden, Raquel Rodríguez-González, José L. Martín-Barrasa, Sonia García-Hernández, Ángela Ramos-Nuez, H. Celeste González-García, Jesús M. González-Martín, Robert M. Kacmarek, Jesús Villar

Publikováno v: Mediators of Inflammation, Vol 2020 (2020)

Supplemental oxygen is a supportive treatment in patients with sepsis to balance tissue oxygen delivery and demand in the tissues. However, hyperoxia may induce some pathological effects. We sought to assess organ damage associated with hyperoxia and

Externí odkaz: https://doaj.org/article/b08219e9f7fd4265bdd7dc510213c983

Inhaled Nitric Oxide Delivery Systems for Mechanically Ventilated and Nonintubated Patients: A Review

Autor: Robert M. Kacmarek, Stefano Gianni, Ryan W. Carroll, Lorenzo Berra

Publikováno v: Respiratory Care. 66:1021-1028

Nitric oxide (NO) is a biologically active molecule approved for the treatment of pulmonary hypertension in newborn patients. Commercially available NO delivery systems use pressurized cylinders as the source of NO and a sensor to control the concent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5aabea99cfaf5f7f025f7e5f1a1a51c
https://doi.org/10.4187/respcare.08856

Weaning patients with obesity from ventilatory support

Autor: Lorenzo Berra, Robert M. Kacmarek, Hatus V. Wanderley, Jesús Villar

Publikováno v: Current Opinion in Critical Care. 27:311-319

Purpose of review Obesity prevalence is increasing in most countries in the world. In the United States, 42% of the population is obese (body mass index (BMI) > 30) and 9.2% is obese class III (BMI > 40). One of the greatest challenges in critically

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd48611dd63caae21cb304519c8dd638
https://doi.org/10.1097/mcc.0000000000000823