Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Robert Leclaire"'
Publikováno v:
Drug metabolism reviews. 29(1-2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b4b92c3219fae692fed0fea1897199
https://pubmed.ncbi.nlm.nih.gov/9187520
https://pubmed.ncbi.nlm.nih.gov/9187520
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 231:467-472
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce72c48e94ccc100790f4c3c35faeb38
https://doi.org/10.1016/s0378-4347(00)81874-5
https://doi.org/10.1016/s0378-4347(00)81874-5
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 183:346-351
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081473d8865c37608b7a4e48886cf5e9
https://doi.org/10.1016/s0378-4347(00)81715-6
https://doi.org/10.1016/s0378-4347(00)81715-6
Autor:
Robert Leclaire, Besner Jg, Michele Deschamps, Attilio de Sanctis, Pierre Gervais, Pierre R. Band
Publikováno v:
Oncology. 41:66-68
12 patients with metastatic cancer were treated with the substituted indazole carboxylic acid Lonidamine at oral daily doses of 270 mg/m2. Toxicity, consisting mainly of myalgias, somnolence, hyperesthesia, anorexia and vomiting, generally decreased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2588f807427f8b5b418505375cfa71
https://doi.org/10.1159/000225889
https://doi.org/10.1159/000225889
Autor:
Pierre R. Band, Marco Gobbi, Attilio De Sanctis, M. Bellocci, C. Gallo Curcio, B. Catanese, Sante Tura, P. Giannotti, A. Fabbrini, Luigi Aloe, R. Cavaliere, G. Pacilio, Delle Chiaie, T. Battelli, W. Malorni, Franco Di Filippo, Maureen A. O’Hehir, Walter Malorni, Felice Salsano, R. Mattioli, Cm. Carapella, Giovanni Battista Ciottoli, Alessandro Marolla, R. Tonachella, G. Carteni, M. Rinaldi, A. Barduagni, C.W. Young, M. Nardi, Robert Leclaire, S. D’Atri, A. Alfieri, Fouad M. Farag, Di Lauro, Lorenzo Magno, J.-G. Besner, Anna Calabro, Fabrizia Terraneo, Jae Ho Kim, B. Silvestrini, Antonio Varanese, D. Manocchi, O. Kokron, R. Leclaire, S. Maca, G. Tullio, M. De Cesare, James E. Kinahan, L. Giustini, Patrizia Franchi, A. Floridi, Anna Nista, Jean-Guy Besner, M.G. Paggi, Gallo Curcio, A. Ginnetti, A. Caputo, Bruno Silvestrini, Loredana Piarulli, M.L. Marcante, Charles W. Young, C.D. De Martinet, W. Scheiner, Sandro Carlini, W.K. Evans, M. Gallo, S.H. Kim, G.B. Ciottoli, Michele Deschamps, Cesare De Martino, F. Ambrogi, P.R. Band, Michele Cavo, G. Iapadre, Pierre Gervais, C. De Martino, Violante Currie, M. De Gregorio, Marina Viora, F. Di Filippo, J.H. Kim, B. Mullis, M. Deschamps, F.A. Shepherd, M. Biglietto, A.J. De Sanctis, A. Riccio, M. Barduagni, Alan A. Alfieri, Sang Hie Kim, B. Iandolo, Pier Giorgio Natali, P. Manocchi, Renato Cavaliere, A. Nista, V. Santiemma
Publikováno v:
Oncology. 41:I-III
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1421267fddbc9c832add7cf84e5a351a
https://doi.org/10.1159/000225880
https://doi.org/10.1159/000225880
Publikováno v:
Oncology. 41
15 patients with metastatic cancer were treated with Lonidamine, a substituted indazole carboxylic acid active against the Lewis lung and Sarcoma 180 tumors. Single doses of 600 mg (350-400 mg/m2) mostly induced somnolence and gastro-intestinal side
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b011a2eb1d288058baf5b96c89a890
https://pubmed.ncbi.nlm.nih.gov/6717896
https://pubmed.ncbi.nlm.nih.gov/6717896
Autor:
Robert Leclaire, Lino Liverani, Attilio de Sanctis, Besner Jg, Pierre R. Band, Pierre Gervais, Michelle Deschamps, Sylvie Mailhot
Publikováno v:
Journal of chromatography. 277
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::667708ff27206519cf72366ce4c5eb59
https://pubmed.ncbi.nlm.nih.gov/6643634
https://pubmed.ncbi.nlm.nih.gov/6643634
Publikováno v:
Oncology. 41
The pharmacokinetics of Lonidamine has been studied in cancer patients after single and chronic oral administrations. After single administration the plasma kinetics are highly variable, while the dose eliminated in the urine is over 70% in all subje
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729b99ec7f101ddfd63fbd738e14db2b
https://pubmed.ncbi.nlm.nih.gov/6717895
https://pubmed.ncbi.nlm.nih.gov/6717895
Autor:
Michele Deschamps, Besner Jg, Robert Leclaire, G. Diorio, M. Gélinas, D. Larochelle, C. Girard, Pierre R. Band
Publikováno v:
Journal of Urology. 130:401-401
A phase I study of 13-cis-retinoic acid was done in 16 patients with head and neck malignancies using a modified Fibonacci search scheme, with individual doses ranging from 20 to 120 mg/m2. Drug doses greater than 60 mg/m2 induced intense headaches,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10b0e73c4ee3718569d3f096063105c6
https://doi.org/10.1016/s0022-5347(17)51179-9
https://doi.org/10.1016/s0022-5347(17)51179-9
Periodical
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