Zobrazeno 1 - 10
of 248
pro vyhledávání: '"Robert Landsiedel"'
Autor:
Tizia Thoma, Lan Ma-Hock, Steffen Schneider, Naveed Honarvar, Silke Treumann, Sibylle Groeters, Volker Strauss, Heike Marxfeld, Dorothee Funk-Weyer, Svenja Seiffert, Wendel Wohlleben, Martina Dammann, Karin Wiench, Noömi Lombaert, Christine Spirlet, Marie Vasquez, Nicole Dewhurst, Robert Landsiedel
Publikováno v:
Particle and Fibre Toxicology, Vol 21, Iss 1, Pp 1-29 (2024)
Abstract Background Significant variations exist in the forms of ZnO, making it impossible to test all forms in in vivo inhalation studies. Hence, grouping and read-across is a common approach under REACH to evaluate the toxicological profile of fami
Externí odkaz:
https://doaj.org/article/06d6ea29b11a4bd6a212be4233a9c279
Autor:
Christiane Hindrichs, Tilmann Walk, Robert Landsiedel, Hennicke Kamp, Steffen Schneider, Stephanie Melching-Kollmuss, Dorothee Funk-Weyer
Publikováno v:
Metabolites, Vol 14, Iss 1, p 61 (2024)
Changes in thyroid hormone (TH) levels in rat brain at early developmental stages are correlated with adverse effects on offspring development. To characterize the ability of substances to interfere with the TH concentrations in, e.g., rat brain, it
Externí odkaz:
https://doaj.org/article/e2ac1be61b4943dfa9076064619b68e9
Autor:
Robert Landsiedel, Daniela Hahn, Rainer Ossig, Sabrina Ritz, Lydia Sauer, Roland Buesen, Sascha Rehm, Wendel Wohlleben, Sibylle Groeters, Volker Strauss, Saskia Sperber, Haleluya Wami, Ulrich Dobrindt, Karola Prior, Dag Harmsen, Bennard van Ravenzwaay, Juergen Schnekenburger
Publikováno v:
Particle and Fibre Toxicology, Vol 19, Iss 1, Pp 1-20 (2022)
Abstract Background The oral uptake of nanoparticles is an important route of human exposure and requires solid models for hazard assessment. While the systemic availability is generally low, ingestion may not only affect gastrointestinal tissues but
Externí odkaz:
https://doaj.org/article/f44a66b7252642c58957e23656e01438
Autor:
Andrea Morger, Miriam Mathea, Janosch H. Achenbach, Antje Wolf, Roland Buesen, Klaus-Juergen Schleifer, Robert Landsiedel, Andrea Volkamer
Publikováno v:
Journal of Cheminformatics, Vol 12, Iss 1, Pp 1-17 (2020)
Abstract Risk assessment of newly synthesised chemicals is a prerequisite for regulatory approval. In this context, in silico methods have great potential to reduce time, cost, and ultimately animal testing as they make use of the ever-growing amount
Externí odkaz:
https://doaj.org/article/e4aa961fd8df42b29145d5bd1a6dc7ad
Publikováno v:
Cosmetics, Vol 9, Iss 1, p 22 (2022)
In the last two decades, great strides have been made in developing alternative methods to animal testing for regulatory and safety testing. In 2021, a breakthrough in regulatory testing was achieved in that the first test strategies employing non-an
Externí odkaz:
https://doaj.org/article/002b131284e745c6bf3372d6851ba685
Autor:
Johannes G. Keller, Uschi M. Graham, Johanna Koltermann-Jülly, Robert Gelein, Lan Ma-Hock, Robert Landsiedel, Martin Wiemann, Günter Oberdörster, Alison Elder, Wendel Wohlleben
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/b8b081b272044402b2cff23adb79dad1
Publikováno v:
Nanomaterials, Vol 10, Iss 2, p 311 (2020)
Dissolution rates of nanomaterials can be decisive for acute in vivo toxicity (via the released ions) and for biopersistence (of the remaining particles). Continuous flow systems (CFSs) can screen for both aspects, but operational parameters need to
Externí odkaz:
https://doaj.org/article/f8c5f4df29544c6da2a8efea6649bb21
Autor:
Martin Wiemann, Ursula G. Sauer, Antje Vennemann, Sandra Bäcker, Johannes-Georg Keller, Lan Ma-Hock, Wendel Wohlleben, Robert Landsiedel
Publikováno v:
Nanomaterials, Vol 8, Iss 3, p 160 (2018)
In vitro prediction of inflammatory lung effects of well-dispersed nanomaterials is challenging. Here, the in vitro effects of four colloidal amorphous SiO2 nanomaterials that differed only by their primary particle size (9, 15, 30, and 55 nm) were a
Externí odkaz:
https://doaj.org/article/61d1defe6df841468e62586cd144ff12
Publikováno v:
Biochemical and Biophysical Research Communications. 651:114-120
Autor:
Andreas Georg Weber, Barbara Birk, Chantal Herrmann, Hans-Albrecht Huener, Kostja Renko, Sandra Coecke, Steffen Schneider, Dorothee Funk-Weyer, Robert Landsiedel
Publikováno v:
Applied In Vitro Toxicology. 8:67-82