Zobrazeno 1 - 10
of 275
pro vyhledávání: '"Robert Landick"'
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Terpenoids are a diverse class of compounds with wide-ranging uses including as industrial solvents, pharmaceuticals, and fragrances. Efforts to produce terpenoids sustainably by engineering microbes for fermentation are ongoing, but industrial produ
Externí odkaz:
https://doaj.org/article/994ca67452c2478aa47f1a4f92c55af2
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Expression of virulence genes in pathogenic Escherichia coli is controlled in part by the transcription silencer H-NS and its paralogs (e.g., StpA), which sequester DNA in multi-kb nucleoprotein filaments to inhibit transcription initiation,
Externí odkaz:
https://doaj.org/article/b1f0eae1456c4204903bd54899b2728e
Publikováno v:
Microbial Cell, Vol 9, Iss 7, Pp 136-138 (2022)
Clostridioides difficile (Cdiff) infection (CDI) continues to be the leading threat of nosocomial deaths worldwide and a major burden on health-care systems. Broad-spectrum antibiotics eradicate the normal gut microbiome, killing protective commensal
Externí odkaz:
https://doaj.org/article/f785248acab24872bb717747d2df4b75
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104429- (2022)
Summary: Gene silencing in bacteria is mediated by chromatin proteins, of which Escherichia coli H-NS is a paradigmatic example. H-NS forms nucleoprotein filaments with either one or two DNA duplexes. However, the structures, arrangements of DNA-bind
Externí odkaz:
https://doaj.org/article/1ae1a209bcb34084aca369f0cce5d203
CRISpy-Pop: A Web Tool for Designing CRISPR/Cas9-Driven Genetic Modifications in Diverse Populations
Autor:
Hayley R. Stoneman, Russell L. Wrobel, Michael Place, Michael Graham, David J. Krause, Matteo De Chiara, Gianni Liti, Joseph Schacherer, Robert Landick, Audrey P. Gasch, Trey K. Sato, Chris Todd Hittinger
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 11, Pp 4287-4294 (2020)
Externí odkaz:
https://doaj.org/article/e369f5c5d0ac4106b0c9b04e088a9732
Autor:
Timothy T. Harden, Karina S. Herlambang, Mathew Chamberlain, Jean-Benoît Lalanne, Christopher D. Wells, Gene-Wei Li, Robert Landick, Ann Hochschild, Jane Kondev, Jeff Gelles
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
In the canonical bacterial transcription, both nascent transcript and polymerase dissociate from template DNA. By employing multi-color single-molecule fluorescence imaging, here the authors show that RNA polymerases remain bound to DNA after the tra
Externí odkaz:
https://doaj.org/article/13f680680f904593b7b3498bafa4968b
Autor:
Piyush Behari Lal, Fritz M. Wells, Yucai Lyu, Indro N. Ghosh, Robert Landick, Patricia J. Kiley
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/b54a2df3929e4131be8fdcfa49940990
Autor:
Jessica M. Vera, Indro Neil Ghosh, Yaoping Zhang, Alex S. Hebert, Joshua J. Coon, Robert Landick
Publikováno v:
mSystems, Vol 5, Iss 4 (2020)
ABSTRACT Zymomonas mobilis is an ethanologenic alphaproteobacterium with promise for the industrial conversion of renewable plant biomass into fuels and chemical bioproducts. Limited functional annotation of the Z. mobilis genome is a current barrier
Externí odkaz:
https://doaj.org/article/98dfd904d3eb43e6ad31f20b0a67b42d
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0226235 (2020)
Plant-derived fuels and chemicals from renewable biomass have significant potential to replace reliance on petroleum and improve global carbon balance. However, plant biomass contains significant fractions of oligosaccharides that are not usable nati
Externí odkaz:
https://doaj.org/article/f782b4bc53d74dc5a1757c32c812c4aa
Autor:
Yaoping Zhang, Jessica M. Vera, Dan Xie, Jose Serate, Edward Pohlmann, Jason D. Russell, Alexander S. Hebert, Joshua J. Coon, Trey K. Sato, Robert Landick
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Utilization of both C5 and C6 sugars to produce biofuels and bioproducts is a key goal for the development of integrated lignocellulosic biorefineries. Previously we found that although engineered Zymomonas mobilis 2032 was able to ferment glucose to
Externí odkaz:
https://doaj.org/article/4bcab52504294d2598ed3666c9618f18