Prognostic Utility of Estimated Pulmonary Dead Space to Tidal Volume Fraction in Patients With COVID-19 Respiratory Failure Treated With Invasive Mechanical Ventilation

Autor: David C. Frankenfield, Paula A. Valencia-Moulton, Erik Lehman, Robert L. Vender

Publikováno v: Clinical Infection and Immunity. 6:6-10

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c542c76c6d3efe5ec940050cfbf27fe
https://doi.org/10.14740/cii126

Long-term treatment with oral N-acetylcysteine: Affects lung function but not sputum inflammation in cystic fibrosis subjects. A phase II randomized placebo-controlled trial

Autor: Richard B. Moss, Jonathan E. Spahr, Carol Conrad, Peter H. Michelson, James Lymp, C. Dunn, John P. Clancy, Z. Davies, Leonore A. Herzenberg, Ronald C. Rubenstein, Marie E. Egan, Christopher H. Goss, L. Quittell, David P. Nichols, Robert L. Vender, Rabindra Tirouvanziam, Valeria Thompson, Barbara A. Chatfield, Veena B. Antony

Publikováno v: Journal of Cystic Fibrosis. 14(2):219-227

To evaluate the effects of oral N-acetylcysteine (NAC), which replenishes systemic glutathione, on decreasing inflammation and improving lung function in CF airways.A multicenter, randomized, double-blind proof of concept study in which 70 CF subject

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b09addd0c7edc3095f9e6d38042f31

Cystic Fibrosis Pulmonary Guidelines

Autor: Randall L. Rosenblatt, Daniel Rosenbluth, Marcia Katz, Henry L. Dorkin, Patrick A. Flume, Moira L. Aitken, Michelle S. Howenstine, Manu Jain, David C. McGiffin, Joseph M. Pilewski, Ahmet Uluer, Craig W. Lillehei, Beryl J. Rosenstein, Hector H. Gutierrez, Terry B. White, James D. Acton, Randall K. Young, Thomas M. Egan, Kathryn A. Sabadosa, Steven Strausbaugh, Mary K Lester, Sally E. Mitchell, Douglas S. Holsclaw, Bruce C. Marshall, Mike Mulligan, David M. Orenstein, Donna Beth Willey-Courand, Peter J. Mogayzel, Susanna A. McColley, Souheil Saddekni, Melissa Chin, Lynne M. Quittell, Paul Mohabir, Christopher M. Oermann, James R. Yankaskas, Michael P. Boyle, Robert J. Kuhn, R. Duane Davis, Jill Fleige, Michael J. Rock, Elizabeth Tullis, Anne M Downs, James L. Cunningham, Peter J Murphy, John L. Colombo, Linda L. Wolfenden, Thomas W. Ferkol, Patricia M. Joseph, Jeffrey S. Wagener, George Z. Retsch-Bogart, Christopher H. Goss, Karen A. Robinson, Carlos Milla, Felix Ratjen, Michael S. Schechter, Patricia E. Burrows, Aruna Sannuti, Charles B. Huddleston, Robert L. Vender, Leslie Hazle, Mark J. Sands, Charles T. Burke, Wickii T. Vigneswaran, Ronald C. Rubenstein, Guillermo A. doPico, Jerry A. Nick, Wyn Hoover, Mark H. Wholey

Publikováno v: American Journal of Respiratory and Critical Care Medicine. 182:298-306

Cystic fibrosis (CF) is a recessive genetic disease characterized by dehydration of the airway surface liquid and impaired mucociliary clearance. As a result, individuals with the disease have difficulty clearing pathogens from the lung and experienc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee82205e6b63ce9b3731b135f84a4850
https://doi.org/10.1164/rccm.201002-0157oc

The Chronic Critically Ill: Pulmonary Perspective

Autor: Lucina M Vender, Robert L. Vender

Publikováno v: Journal of Nursing & Care.

Robert L Vender1* and Lucina M Vender2 1Department of Medicine, Pulmonary, Allergy, Critical Care Medicine, Penn State Milton S. Hershey Medical Center, USA 2Instructor of Nursing, College of Nursing, Pennsylvania State University, USA *Corresponding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::403a37f7b2002f918f1c70c00a1776ea
https://doi.org/10.4172/2167-1168.1000239

Prediction equation to estimate dead space to tidal volume fraction correlates with mortality in critically ill patients

Autor: Robert L. Vender, Dan A. Galvan, Manuel F. Betancourt, David C. Frankenfield, Erik Lehman, Christopher Harrell

Publikováno v: Journal of critical care. 29(2)

Objective The measurement of dead space to tidal volume fraction (Vd/Vt) using various methodologies has been shown to be a reliable predictor of mortality in critically ill patients. In this study, we evaluated the correlation of a validated equatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f838c9246f1dec53f3797fce65c45ac1
https://pubmed.ncbi.nlm.nih.gov/24581935