Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Robert L. Unckless"'
Autor:
Kim L. Vertacnik, Danielle K. Herrig, R. Keating Godfrey, Tom Hill, Scott M. Geib, Robert L. Unckless, David R. Nelson, Catherine R. Linnen
Publikováno v:
Ecology and Evolution, Vol 13, Iss 10, Pp n/a-n/a (2023)
Abstract A central goal in evolutionary biology is to determine the predictability of adaptive genetic changes. Despite many documented cases of convergent evolution at individual loci, little is known about the repeatability of gene family expansion
Externí odkaz:
https://doaj.org/article/18ab478f05ff4d0b9d5a67224481790f
Autor:
Matthew E. Ochs, Rebecca M. McWhirter, Robert L. Unckless, David M. Miller, Erik A. Lundquist
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-20 (2022)
Abstract Migration of neuroblasts and neurons from their birthplace is central to the formation of neural circuits and networks. ETR-1 is the Caenorhabditis elegans homolog of the CELF1 (CUGBP, ELAV-like family 1) RNA-processing factor involved in ne
Externí odkaz:
https://doaj.org/article/e3294866cb8e4854be5337b17e648de7
Autor:
Tom Hill, Robert L. Unckless
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3575-3582 (2019)
Copy number variants (CNV) are associated with phenotypic variation in several species. However, properly detecting changes in copy numbers of sequences remains a difficult problem, especially in lower quality or lower coverage next-generation sequen
Externí odkaz:
https://doaj.org/article/ba44e60bc6b24ec187e15a04c00cefc2
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 9, Pp 3145-3155 (2017)
Postcopulatory sexual selection (PCSS) is a potent evolutionary force that can drive rapid changes of reproductive genes within species, and thus has the potential to generate reproductive incompatibilities between species. Male seminal fluid protein
Externí odkaz:
https://doaj.org/article/628f4dbf911f4f36ad932f8ab33309e4
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
There is a developing interest in how immune genes may function in other physiological roles, and how traditionally non-immune peptides may, in fact, be active in immune contexts. In the absence of infection, the induction of the immune response is c
Externí odkaz:
https://doaj.org/article/61cabec23e7141029f03b8a77c5d5ebd
Autor:
Jessamyn I Perlmutter, Joanne R Chapman, Mason C Wilkinson, Isaac Nevarez-Saenz, Robert L Unckless
Publikováno v:
PLoS Genetics, Vol 20, Iss 3, p e1011155 (2024)
Antimicrobial peptides (AMPs) are at the interface of interactions between hosts and microbes and are therefore expected to be rapidly evolving in a coevolutionary arms race with pathogens. In contrast, previous work demonstrated that insect AMPs ten
Externí odkaz:
https://doaj.org/article/23ff312ea92f4f8f934e01f14f099829
Autor:
Tom Hill, Robert L Unckless
Publikováno v:
eLife, Vol 9 (2020)
Hosts and viruses are constantly evolving in response to each other: as a host attempts to suppress a virus, the virus attempts to evade and suppress the host’s immune system. Here, we describe the recurrent evolution of a virulent strain of a DNA
Externí odkaz:
https://doaj.org/article/a323e83f6ca944e29bea41fbe0eb2c87
Autor:
María Angélica Bravo Núñez, Ibrahim M Sabbarini, Lauren E Eide, Robert L Unckless, Sarah E Zanders
Publikováno v:
eLife, Vol 9 (2020)
Killer meiotic drivers are genetic parasites that destroy ‘sibling’ gametes lacking the driver allele. The fitness costs of drive can lead to selection of unlinked suppressors. This suppression could involve evolutionary tradeoffs that compromise
Externí odkaz:
https://doaj.org/article/fe893d4b514a4c8aa858dad961d76f5e
Autor:
Elizabeth ML Duxbury, Jonathan P Day, Davide Maria Vespasiani, Yannik Thüringer, Ignacio Tolosana, Sophia CL Smith, Lucia Tagliaferri, Altug Kamacioglu, Imogen Lindsley, Luca Love, Robert L Unckless, Francis M Jiggins, Ben Longdon
Publikováno v:
eLife, Vol 8 (2019)
It is common to find considerable genetic variation in susceptibility to infection in natural populations. We have investigated whether natural selection increases this variation by testing whether host populations show more genetic variation in susc
Externí odkaz:
https://doaj.org/article/624025c10f434438a89a90bb98bd816b
Autor:
Yousef M. Alhammad, Srivatsan Parthasarathy, Roshan Ghimire, Joseph J. O’Connor, Catherine M. Kerr, Jessica J. Pfannenstiel, Debarati Chanda, Caden A. Miller, Robert L. Unckless, Sonia Zuniga, Luis Enjuanes, Sunil More, Rudragouda Channappanavar, Anthony R. Fehr
Several coronavirus (CoV) encoded proteins are being evaluated as targets for antiviral therapies for COVID-19. Included in this set of proteins is the conserved macrodomain, or Mac1, an ADP-ribosylhydrolase and ADP-ribose binding protein. Utilizing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de8f7884609360a09184a0574459cb07
https://doi.org/10.1101/2023.04.06.535927
https://doi.org/10.1101/2023.04.06.535927
