Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Robert L. Susick"'
Autor:
Russell J. Mumper, Robert L. Susick, Michael Jay, Bushra J. Agha, Erik Pacyniak, Melanie Doyle-Eisele, James E. Huckle, Raymond A. Guilmette, Matthew P. Sadgrove, Marina G.D. Leed, Waylon Weber
Publikováno v:
International journal of radiation biology. 91(7)
Currently two injectable products of diethylenetriaminepentaacetic acid (DTPA) are U.S. Food and Drug Administration (FDA)-approved for decorporation of (241)Am; however, an oral product is considered more amenable in a mass casualty situation. The d
Autor:
Robert L. Hall, Haig P. Bozigian, Lorrene Buckley Kedderis, Steadman D. Harrison, Robert L. Susick, James M. Kleeman, Thomas E. Palmer
Publikováno v:
Fundamental and Applied Toxicology. 25:201-217
Toxicity of the Protein Kinase C Inhibitor Safingol Administered Alone and in Combination with Chemotherapeutic Agents. Kedderis, L. B., Bozigian, H. P., Kleeman, J. M., Hall, R. L., Palmer, T. E., Harrison, S. D., Jr., and Susick, R. L., Jr. (1995).
Publikováno v:
Journal of Cardiovascular Pharmacology. 2:268-282
Angiotensin-converting enzyme (ACE) inhibitors have proven to be effective therapeutic agents for treatment of hypertension and congestive heart failure (CHF). Because of the role the renin-angiotensin system (RAS) plays in maintaining renal homeosta
Publikováno v:
Journal of Cardiovascular Pharmacology. 19:282-289
Angiotensin-converting enzyme (ACE) inhibitors have adverse effects on renal function in some hypertensive patients, and some of them produce renal tubular lesions in animals at high doses. To assess the effect of quinapril on renal function and stru
Publikováno v:
Toxicology and applied pharmacology. 137(2)
Safingol [(2S,3S)-2-amino-1,3-octadecanediol], a sphingosine analog that inhibits protein kinase C, was developed to treat dermatoses and cancer. Preclinical toxicology studies performed to assess the effects of safingol showed that 6 weeks of dermal
Autor:
Vincent G. Zannoni, Robert L. Susick
Publikováno v:
Clinical Pharmacology and Therapeutics. 41:502-509
This study examines the influence of ascorbic acid pretreatment on ethanol clearance, toxicity, and behavioral impairment after an acute dose of ethanol in humans. Ascorbic acid or a placebo was given to 20 healthy male subjects for 2 weeks before et
Autor:
Robert L. Susick, Vincent G. Zannoni
Publikováno v:
Alcoholism: Clinical and Experimental Research. 11:265-268
Male guinea pigs were maintained on a vitamin C-deficient chow diet and supplemented with either 0.05 or 2.0 mg of ascorbic acid/ml drinking water for 3 weeks prior to receiving an intraperitoneal injection of 4.0 g of ethanol/kg body weight. The fol
Autor:
Kedderis, Lorrene Buckley, Bozigian, Haig P., Kleeman, James M., Hall, Robert L., Palmer, Thomas E., Jr., Steadman D. Harrison, Jr., Robert L. Susick
Publikováno v:
Fundamental and Applied Toxicology; May 1995, Vol. 25 Issue: 2 p201-217, 17p
Publikováno v:
Annals of the New York Academy of Sciences. 498
Autor:
Vincent G. Zannoni, Robert L. Susick
Publikováno v:
Biochemical pharmacology. 33(24)
Methanol and ethanol were rapidly metabolized to formaldehyde and acetaldehyde in the presence of ascorbate, 1,10-phenanthroline and either guinea pig hepatic 100,000 g supernatant or 12,000 g pellet fractions. The specific activity of methanol oxida