Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Robert L. Steward"'
Publikováno v:
Swiss Medical Weekly, Vol 143, Iss 1112 (2013)
Cells reside in mechanically rich and dynamic microenvironments, and the complex interplay between mechanics and biology is widely acknowledged. Recent research has yielded insights linking the mechanobiology of cells, human physiology, and pathophys
Externí odkaz:
https://doaj.org/article/12ce517d594c47ba9c361f804ec71bb0
Publikováno v:
Journal of Biomedical Materials Research Part A. 109:1990-2000
Breast cancer (BCa) is one of the most common cancers for women and metastatic BCa causes the majority of deaths. The extracellular matrix (ECM) stiffens during cancer progression and provides biophysical signals to modulate proliferation, morphology
Publikováno v:
Cytoskeleton (Hoboken)
The human brain microvasculature is constantly exposed to variable fluid flow regimes and their influence on the endothelium depends in part on the synchronous cooperative behavior between cell-cell junctions and the cytoskeleton. In this study, we e
Autor:
Robert L. Steward, Md. Mydul Islam
Publikováno v:
Experimental Mechanics. 59:327-336
The endothelium has been established to generate intercellular stresses and suggested to transmit these intercellular stresses through cell-cell junctions, such as VE-Cadherin and ZO-1, for example. Although the previously mentioned molecules reflect
Publikováno v:
Experimental cell research. 406(2)
Astrocytes are essential to brain homeostasis and their dysfunction can have devastating consequences on human quality of life. Such deleterious effects are generally due in part to changes that occur at the cellular level, which may be biochemical o
Publikováno v:
Biophys J
The interplay between cell-cell and cell-substrate interactions is complex yet necessary for the formation and healthy functioning of tissues. The same mechanosensing mechanisms used by the cell to sense its extracellular matrix also play a role in i
Autor:
Michael R. Behrens, Zhicheng Long, Haley C. Fuller, Md. Mydul Islam, Robert L. Steward, Jingwen Wu, Emily R. Swist, Warren C. Ruder
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Microfluidic technologies are frequently employed as point-of-care diagnostic tools for improving time-to-diagnosis and improving patient outcomes in clinical settings. These microfluidic devices often are designed to operate with peripheral equipmen
Autor:
Robert L. Steward, Md. Mydul Islam
Publikováno v:
Journal of Visualized Experiments.
Endothelial cells have been established to generate intercellular stresses and tractions, but the role gap junctions play in endothelial intercellular stress and traction generation is currently unknown. Therefore, we present here a mechanics-based p
Publikováno v:
Physics of Life Reviews. :120-122
Publikováno v:
Micromachines
Micromachines, Vol 11, Iss 898, p 898 (2020)
Micromachines, Vol 11, Iss 898, p 898 (2020)
Lab-on-a-chip technologies have allowed researchers to acquire a flexible, yet relatively inexpensive testbed to study one of the leading causes of death worldwide, cardiovascular disease. Cardiovascular diseases, such as peripheral artery disease, a