Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Robert L. Somers"'
Autor:
Edward N. Timofeev, Sergey N. Mikhailov, Marc M. Lemaitre, Andrei N. Zuev, Piet Herdewijn, Ekaterina V. Efimtseva, Robert L. Somers
Publikováno v:
Helvetica Chimica Acta. 90:928-937
2′-Deoxy-1-methyladenosine was incorporated into synthetic oligonucleotides by phosphoramidite chemistry. Chloroacetyl protecting group and controlled anhydrous deprotection conditions were used to avoid Dimroth rearrangement. Hybridization studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35f2a3e6f4e9f0a4e8c35a7655095199
https://doi.org/10.1002/hlca.200790093
https://doi.org/10.1002/hlca.200790093
Autor:
Anthony D. Sercel, John B. Randolph, Kee-Yong Jung, Dean S. Wise, Hugh Mackie, Robert L. Somers, William H. Pearson, David A. Berry
Publikováno v:
Tetrahedron Letters. 45:2457-2461
Pyrrolo-dC ( 1a , 6-methyl-3-(2-deoxy-β- d -ribofuranosyl)-3 H -pyrrolo[2,3- d ]pyrimidin-2-one) and its cyanoethyl phosphoramidite 2a were synthesized. The latter was incorporated into oligodeoxyribonucleotides by standard automated synthesis techn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4569e09edd30329b614b60d28056198c
https://doi.org/10.1016/j.tetlet.2004.01.108
https://doi.org/10.1016/j.tetlet.2004.01.108
Publikováno v:
Journal of Biological Chemistry. 276:36051-36057
8,5′-Cyclopurine-2′-deoxynucleotides, which are strong blocks to mammalian DNA and RNA polymerases, represent a novel class of oxidative DNA lesion in that they are specifically repaired by nucleotide excision repair but not by base excision repa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e48e550132dd1b9b8c10dde4a77a6c7a
https://doi.org/10.1074/jbc.m105472200
https://doi.org/10.1074/jbc.m105472200
Autor:
Michael J. Smerdon, Alexander Y. Spoonde, Dean S. Wise, Katherine G. Coleman, David A. Berry, Hugh Mackie, Eric J. Ackerman, Philip J. Brooks, Robert L. Somers, Joseph V. Kosmoski, Robert E. Tarone, Jay H. Robbins
Publikováno v:
Journal of Biological Chemistry. 275:22355-22362
Xeroderma pigmentosum (XP) patients with inherited defects in nucleotide excision repair (NER) are unable to excise from their DNA bulky photoproducts induced by UV radiation and therefore develop accelerated actinic damage, including cancer, on sun-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72a4aac882acc532bf419757c91bbe2a
https://doi.org/10.1074/jbc.m002259200
https://doi.org/10.1074/jbc.m002259200
Autor:
Sergey N. Mikhailov, Robert L. Somers, Piet Herdewijn, Marc M. Lemaitre, Andrei N. Zuev, Ekaterina V. Efimtseva, Edward N. Timofeev
Publikováno v:
ChemInform. 38
2′-Deoxy-1-methyladenosine was incorporated into synthetic oligonucleotides by phosphoramidite chemistry. Chloroacetyl protecting group and controlled anhydrous deprotection conditions were used to avoid Dimroth rearrangement. Hybridization studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a3d1952dd79f6dbe03e25f56cabcf36
https://doi.org/10.1002/chin.200731166
https://doi.org/10.1002/chin.200731166
Autor:
Hitoshi Shichi, Robert L. Somers
Publikováno v:
Journal of Biological Chemistry. 249:6570-6577
Rhodopsin regeneration from opsin and all-trans-retinal involves two discrete reactions: isomerization of all-trans-retinal to 11-cis-retinal and binding of 11-cis-retinal with opsin. We have previously found that phospholipid stimulates the photic r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f757ed159706b654353fdec248768d9
https://doi.org/10.1016/s0021-9258(19)42194-7
https://doi.org/10.1016/s0021-9258(19)42194-7
Publikováno v:
Neurochemistry International. 13:81-87
The phosphorylation of interphotoreceptor retinoid-binding protein (IRBP), the major soluble (glycolipo) protein of the interphotoreceptor matrix (IPM) and a putative intercellular retinoid-transport vechicle, has been examined in a crude bovine IPM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4bed04d217612631634ca7b4932999
https://doi.org/10.1016/0197-0186(88)90106-4
https://doi.org/10.1016/0197-0186(88)90106-4
Autor:
Hitoshi Shichi, Robert L. Somers
Publikováno v:
Photochemistry and Photobiology. 22:187-191
— Rhodopsin regeneration in rod membranes involves reactions of all-trans retinal (released from bleached pigment) with phosphatidylethanolamine, photic isomerization of retinal, and binding of 11-cis retinal to opsin. This investigation demonstrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57a56100a3b020ce0820358828f7e74
https://doi.org/10.1111/j.1751-1097.1975.tb06735.x
https://doi.org/10.1111/j.1751-1097.1975.tb06735.x
Publikováno v:
Biochemical and Biophysical Research Communications. 61:217-221
Phosphorylation of rod membrane proteins is a light-dependent reaction. Most rhodopsin molecules, however, are not phosphorylated. The protein that is highly phosphorylated (>3 moles phosphate per mole phosphorylated protein) appears to be a rhodopsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::235ab9d1edd07ca46f6257b75c446493
https://doi.org/10.1016/0006-291x(74)90555-5
https://doi.org/10.1016/0006-291x(74)90555-5
Autor:
Hitoshi Shichi, Robert L. Somers
Publikováno v:
The Journal of Biochemistry. 96:1633-1636
The rod GTP-binding protein in the bovine disk membrane seems to exist as oligomers in the dark. G alpha and G beta do not interact strongly, and G gamma may be required for G alpha . GDP to dimerize.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f867e2d77d20119c17c3c988cc3e085
https://doi.org/10.1093/oxfordjournals.jbchem.a134994
https://doi.org/10.1093/oxfordjournals.jbchem.a134994