Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Robert L. Peake"'
Publikováno v:
Postgraduate medicine. 57(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95dfa00b366ced50288a44e4f731be42
https://pubmed.ncbi.nlm.nih.gov/27410788
https://pubmed.ncbi.nlm.nih.gov/27410788
Autor:
Gattadahalli S. Seetharamaiah, Robert L. Peake, John S. Dallas, N. Rao Thotakura, Bellur S. Prabhakar, Sai A. Patibandla
Publikováno v:
Endocrinology. 138:1559-1566
We expressed the extracellular domain of the mouse TSH receptor (mET-gp) using the baculovirus expression system. The recombinant protein was identified as mET-gp by immunoblotting and N-terminal amino acid sequencing. Carbohydrate analysis of the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8efa417c90bf7ca4c35aad3e4c203719
https://doi.org/10.1210/endo.138.4.5093
https://doi.org/10.1210/endo.138.4.5093
Publikováno v:
Hormone Research. 10:191-206
Trypan blue directly inhibited in vitro thyroid secretion (butanol soluble 125I release to the media) induced by both thyroid stimulating hormone (TSH) and dibutyryl cAMP. Intracellular colloid droplet counts were also decreased. Inhibition was direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d651d389c62fd036de697463d3dda7
https://doi.org/10.1159/000179001
https://doi.org/10.1159/000179001
Publikováno v:
Postgraduate Medicine. 57:121-124
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08484b0c1c2908331832e323a37fba31
https://doi.org/10.1080/00325481.1975.11714079
https://doi.org/10.1080/00325481.1975.11714079
Autor:
F. C. Petty, John W. Roberts, Jesse D. Ibarra, Paul F. Gilliland, George Crile, Robert L. Peake
Publikováno v:
Postgraduate Medicine. 57:84-90
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2adcd6d676837d6393f702ab7b464514
https://doi.org/10.1080/00325481.1975.11714075
https://doi.org/10.1080/00325481.1975.11714075
Publikováno v:
The Journal of Pediatrics. 93:57-61
Thyroid antibodies were determined by three different techniques in the sera of 125 children and adolescents with thyroid disorders and in the sera of 53 short, normal children without thyroid dysfunction. The incidence of antithyroglobulin antibodie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09fcb56e54f6a8d0ceeb1cd41e16c5cf
https://doi.org/10.1016/s0022-3476(78)80600-3
https://doi.org/10.1016/s0022-3476(78)80600-3
Autor:
Richard C. Powell, James A. Starrett, William P. Deiss, Kandiah Balasubramaniam, Robert L. Peake
Publikováno v:
Endocrinology. 79:19-27
Differential centrifugation of homogenates of prelabeled dog thyroid tissue provides a fraction, sedimenting between 800 and 15,000 Xg, that contains both colloid droplets and lysosomes. When these fractions from control and TSH-stimulated lobes are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff9a5c36421d9268ae4e78e706d0707
https://doi.org/10.1210/endo-79-1-19
https://doi.org/10.1210/endo-79-1-19
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 148:689-702
1. 1. Secretion of thyroid hormones requires their release from peptide bonds in thyroglobulin. The principal thyroidal protease is lysosomal in location, has an acid pH optimum and has been found to react very slowly against thyroglobulin in vitro .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e1294ca5b04624069f7ddb8c2ba9cb4
https://doi.org/10.1016/0304-4165(67)90042-6
https://doi.org/10.1016/0304-4165(67)90042-6
Publikováno v:
Journal of endocrinological investigation. 6(3)
Trypan blue was previously shown to directly inhibit thyroid secretion following TSH stimulation. Inhibition of both colloid droplet formation and thyroglobulin proteolysis was demonstrated. By observing the characteristic bright red fluorescence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79ed2121aae7d557d84f460c3e76f07
https://pubmed.ncbi.nlm.nih.gov/6619526
https://pubmed.ncbi.nlm.nih.gov/6619526
Publikováno v:
Biochimica et biophysica acta. 660(1)
Previous studies have demonstrated that trypan blue directly inhibits thyroid secretion when the dye is administered in vitro or in vivo. To further study the mechanisms of inhibition, cathepsin D (EC 3.4.23.5) (thyroidal acid proteinase) has been pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2caab18f2c784b17b394687425478589
https://pubmed.ncbi.nlm.nih.gov/7023545
https://pubmed.ncbi.nlm.nih.gov/7023545