Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Robert L. Lester"'
Autor:
Robert L. Lester, David C. White
Publikováno v:
Journal of Lipid Research, Vol 8, Iss 6, Pp 565-568 (1967)
A method for the separation and quantitative estimation of ethanolamine, dimethyl ethanolamine, and monomethyl ethanolamine derived from lipids is described. After acid hydrolysis of the lipids, the bases are extracted from the neutralized hydrolysat
Externí odkaz:
https://doaj.org/article/17150a6e30e74e2b8afc17e81fa434df
Autor:
John C. Dittmer, Robert L. Lester
Publikováno v:
Journal of Lipid Research, Vol 5, Iss 1, Pp 126-127 (1964)
Externí odkaz:
https://doaj.org/article/1607a97df48c42a9bfcdcc6f039d51a6
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1831:726-736
Survival of Saccharomyces cerevisiae cells, like most microorganisms, requires switching from a rapidly dividing to a non-dividing or stationary state. To further understand how cells navigate this switch, we examined sphingolipids since they are key
Publikováno v:
Genetics. 175:65-76
Sphingolipid signaling plays an important role in the regulation of central cellular processes, including cell growth, survival, and differentiation. Many of the essential pathways responsible for sphingolipid biogenesis, and key cellular responses t
Publikováno v:
Progress in Lipid Research. 45:447-465
We describe recent advances in understanding sphingolipid functions and metabolism in the baker's yeast Saccharomyces cerevisiae. One milestone has been reached in yeast sphingolipid research with the complete or nearly complete identification of gen
Publikováno v:
Yeast. 19:573-586
Sphingolipid long chain bases (LCBs) in Saccharomyces cerevisiae, dihydrosphingosine (DHS) and phytosphingosine (PHS) and their phosphates (DHS-P and PHS-P) are thought to play roles in heat stress. However, quantitative studies of LCBs and LCBPs hav
Publikováno v:
Journal of Biological Chemistry. 273:7235-7243
Sphingolipid-related metabolites have been implicated as potential signaling molecules in many studies with mammalian cells as well as in some studies with yeast. Our previous work showed that sphingolipid-deficient strains of Saccharomyces cerevisia
Publikováno v:
Journal of Biological Chemistry. 273:2829-2834
Sphingoid long chain bases have many effects on cells including inhibition or stimulation of growth. The physiological significance of these effects is unknown in most cases. To begin to understand how these compounds inhibit growth, we have studied
Publikováno v:
Journal of Biological Chemistry. 272:16110-16117
To identify genes necessary for sphingolipid synthesis in Saccharomyces cerevisiae we developed a procedure to enrich for mutants unable to incorporate exogenous long chain base into sphingolipids. We show here that a mutant strain, AG84-3, isolated
Autor:
Robert L. Lester, M. Marek Nagiec, Elzbieta E. Nagiec, Gerald B. Wells, Robert C. Dickson, Julie A. Baltisberger
Publikováno v:
Journal of Biological Chemistry. 272:9809-9817
We have identified a Saccharomyces cerevisiae gene necessary for the step in sphingolipid synthesis in which inositol phosphate is added to ceramide to form inositol-P-ceramide, a reaction catalyzed by phosphatidylinositol:ceramide phosphoinositol tr