Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Robert L. Jilka"'
Autor:
Srividhya Iyer, Christian Melendez‐Suchi, Li Han, Giulia Baldini, Maria Almeida, Robert L. Jilka
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 4, Pp 207-218 (2020)
Abstract Increased production of the osteoclastogenic cytokine RANKL is a common feature of pathologic bone loss, but the underlying cause of this increase is poorly understood. The unfolded protein response (UPR) is activated in response to accumula
Externí odkaz:
https://doaj.org/article/5cb1f287abc348089efda90356d74c39
Autor:
Ha-Neui Kim, Jinhu Xiong, Ryan S. MacLeod, Srividhya Iyer, Yuko Fujiwara, Keisha M. Cawley, Li Han, Yonghan He, Jeff D. Thostenson, Elisabeth Ferreira, Robert L. Jilka, Daohong Zhou, Maria Almeida, Charles A. O’Brien
Publikováno v:
JCI Insight, Vol 5, Iss 19 (2020)
In aging mice, osteoclast number increases in cortical bone but declines in trabecular bone, suggesting that different mechanisms underlie age-associated bone loss in these 2 compartments. Osteocytes produce the osteoclastogenic cytokine RANKL, encod
Externí odkaz:
https://doaj.org/article/657c52f5dd0742dba28700a3da2de806
Autor:
Elena Ambrogini, Xuchu Que, Shuling Wang, Fumihiro Yamaguchi, Robert S. Weinstein, Sotirios Tsimikas, Stavros C. Manolagas, Joseph L. Witztum, Robert L. Jilka
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Atherosclerosis and osteoporosis are epidemiologically associated, and oxidation specific epitopes (OSEs), which can be neutralized by innate antibodies, are pathogenic for both. Here, the authors show that mice expressing antibody fragments targeted
Externí odkaz:
https://doaj.org/article/3b5383334d33469ca0d3bacfa1e40cd6
Autor:
Robert L. Jilka, Ha-Neui Kim, Horacio Gomez-Acevedo, Stavros C. Manolagas, Joseph L. Witztum, Elena Ambrogini, Sotirios Tsimikas, Xuchu Que, Michela Palmieri
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, vol 36, iss 1
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Oxidized phospholipids containing phosphocholine (OxPL) are pro-inflammatory lipid peroxidation products that bind to scavenger receptors (SRs), such as Scarb1, and toll-like receptors (TLRs). Excessive OxPL, as found in oxidized low-density lipoprot
Autor:
Maria Almeida, Giulia Baldini, Christian Melendez‐Suchi, Srividhya Iyer, Li Han, Robert L. Jilka
Publikováno v:
FASEB BioAdvances
FASEB BioAdvances, Vol 2, Iss 4, Pp 207-218 (2020)
FASEB BioAdvances, Vol 2, Iss 4, Pp 207-218 (2020)
Increased production of the osteoclastogenic cytokine RANKL is a common feature of pathologic bone loss, but the underlying cause of this increase is poorly understood. The unfolded protein response (UPR) is activated in response to accumulation of m
Autor:
Yonghan He, Yuko Fujiwara, Li Han, Keisha M. Cawley, Daohong Zhou, Jinhu Xiong, Ha-Neui Kim, Ryan S. MacLeod, Charles A. O'Brien, Maria Almeida, Elisabeth Ferreira, Robert L. Jilka, Srividhya Iyer, Jeff D. Thostenson
Publikováno v:
JCI Insight
JCI Insight, Vol 5, Iss 19 (2020)
JCI Insight, Vol 5, Iss 19 (2020)
In aging mice, osteoclast number increases in cortical bone but declines in trabecular bone, suggesting that different mechanisms underlie age-associated bone loss in these 2 compartments. Osteocytes produce the osteoclastogenic cytokine RANKL, encod
Autor:
null Michela Palmieri, null Ha‐Neui Kim, null Horacio Gomez‐Acevedo, null Xuchu Que, null Sotirios Tsimikas, null Robert L Jilka, null Stavros C Manolagas, null Joseph L Witztum, null Elena Ambrogini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b825d67432aeb6927d250dc74f3697e
https://doi.org/10.1002/jbmr.4173/v3/response1
https://doi.org/10.1002/jbmr.4173/v3/response1
Autor:
Horacio Gomez-Acevedo, Sotirios Tsimikas, Ha-Neui Kim, Joseph L. Witztum, Stavros C. Manolagas, Michela Palmieri, Xuchu Que, Elena Ambrogini, Robert L. Jilka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c09d623e21a887dca575053856d0121
https://doi.org/10.1002/jbmr.4173/v2/response1
https://doi.org/10.1002/jbmr.4173/v2/response1
Autor:
Srividhya Iyer, Nukhet Aykin-Burns, Robert L. Jilka, Adriana Marques-Carvalho, Maria Almeida, Stavros C. Manolagas, Aaron Warren, Serra Ucer Ozgurel, Li Han, Filipa Ponte, Haibo Zhao, Kimberly J. Krager, Intawat Nookaew, Ha-Neui Kim, Rafael de Cabo, Vilma A. Sardão
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Loss of estrogens at menopause is a major cause of osteoporosis and increased fracture risk. Estrogens protect against bone loss by decreasing osteoclast number through direct actions on cells of the myeloid lineage. Here, we investigated the molecul
Autor:
David Abraham, Maria Almeida, Elena Ambrogini, Andrew Arnold, Bence Bakos, Clemens Bergwitz, Daniel D. Bikle, John P. Bilezikian, Neil Binkley, Alessandro Bisello, L.F. Bonewald, George Bou-Gharios, Roger Bouillon, Mary L. Bouxsein, Brendan F. Boyce, Steven Boyd, Maria Luisa Brandi, David B. Burr, Laura M. Calvi, Ernesto Canalis, Xu Cao, Geert Carmeliet, Thomas O. Carpenter, Wenhan Chang, Shek Man Chim, Shilpa Choudhary, Sylvia Christakos, Yong-Hee Patricia Chun, Cristiana Cipriani, Roberto Civitelli, Thomas L. Clemens, Michael T. Collins, Caterina Conte, Mark S. Cooper, Jillian Cornish, Serge Cremers, Bess Dawson-Hughes, Benoit de Crombrugghe, Hector F. DeLuca, David W. Dempster, Matthew T. Drake, Patricia Ducy, Frank H. Ebetino, Klaus Engelke, Reinhold G. Erben, David R. Eyre, Charles R. Farber, Marina Feigenson, Mathieu Ferron, Pablo Florenzano, Francesca Fontana, Brian L. Foster, Peter A. Friedman, Seiji Fukumoto, Laura W. Gamer, Thomas J. Gardella, Patrick Garnero, Harry K. Genant, Francesca Giusti, Andy Göbel, David Goltzman, Jeffrey P. Gorski, James Griffith, R. Graham G Russell, Kurt D. Hankenson, Fadil M. Hannan, Stephen E. Harris, Iris R. Hartley, Christine Hartmann, Robert P. Heaney, Geoffrey N. Hendy, Matthew J. Hilton, Lorenz C. Hofbauer, Gill Holdsworth, Yi-Hsiang Hsu, David M. Hudson, Marja Hurley, Karl L. Insogna, Robert L. Jilka, Mark L. Johnson, Rachelle W. Johnson, Glenville Jones, Stefan Judex, Harald Jüppner, Ivo Kalajzic, Gérard Karsenty, Hua Zhu Ke, Sundeep Khosla, Douglas P. Kiel, J. Klein-Nulend, Frank C. Ko, Yasuhiro Kobayashi, Martin Konrad, Paul J. Kostenuik, Christopher S. Kovacs, Richard Kremer, Venkatesh Krishnan, Henry M. Kronenberg, Peter A. Lakatos, Uri A. Liberman, Joseph A. Lorenzo, Conor C. Lynch, Karen M. Lyons, Y. Linda Ma, Christa Maes, Michael Mannstadt, Stavros Manolagas, Robert Marcus, David E. Maridas, Pierre J. Marie, Francesca Marini, Jasna Markovac, T. John Martin, Brya G. Matthews, Antonio Maurizi, Sasan Mirfakhraee, Sharon M. Moe, David G. Monroe, Carolina A. Moreira, Ralph Müller, David S. Musson, Teruyo Nakatani, Dorit Naot, Nicola Napoli, Tally Naveh-Many, Edward F. Nemeth, Thomas L. Nickolas, Michael S. Ominsky, Noriaki Ono, David M. Ornitz, Nicola C. Partridge, Vihitaben S. Patel, J. Wesley Pike, Carol Pilbeam, Lori Plum, John T. Potts, J. Edward Puzas, Tilman D. Rachner, Audrey Rakian, Rubie Rakian, Nora E. Renthal, Julie A. Rhoades (Sterling), Mara Riminucci, Scott J. Roberts, Pamela Gehron Robey, Michael J. Rogers, G. David Roodman, Clifford J. Rosen, Vicki Rosen, David W. Rowe, Janet Rubin, Clinton T. Rubin, Karl P. Schlingmann, Ego Seeman, Markus J. Seibel, Chris Sempos, Dolores M. Shoback, Caroline Silve, Justin Silver, Natalie A. Sims, Frederick R. Singer, Joseph P. Stains, Steve Stegen, Paula H. Stern, Gaia Tabacco, Istvan Takacs, Naoyuki Takahashi, Donovan Tay, Anna Teti, Rajesh V. Thakker, Ryan E. Tomlinson, Francesco Tonelli, Dwight A. Towler, Elena Tsourdi, Chia-Ling Tu, Nobuyuki Udagawa, Connie M. Weaver, Marc N. Wein, Lee S. Weinstein, MaryAnn Weis, Michael P. Whyte, Bart O. Williams, Xin Xu, Shoshana Yakar, Yingzi Yang, Stefano Zanotti, Hong Zhou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2162747567c86b8ab39eb70afb5eead5
https://doi.org/10.1016/b978-0-12-814841-9.01002-2
https://doi.org/10.1016/b978-0-12-814841-9.01002-2