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Autor:
Petra Meeuwse, Robert L. J. M. Herpers, C.A.G.M. Weijers, Ernst J. R. Sudhölter, Maurice C. R. Franssen
Publikováno v:
Journal of Organic Chemistry, 70(17), 6639-6646
Journal of Organic Chemistry 70 (2005) 17
Journal of Organic Chemistry 70 (2005) 17
[GRAPHICS] The kinetic resolution of a range of methyl-substituted 1-oxaspiro[2.5]octanes by yeast epoxide hydrolase (YEH) from Rhodotorula glutinis has been investigated. The structural determinants of substrate specificity and stereoselectivity of