Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Robert L. Geahlen"'
Autor:
Lingfei Zeng, Wen-Horng Wang, Justine Arrington, Gengbao Shao, Robert L. Geahlen, Chang-Deng Hu, W. Andy Tao
Publikováno v:
ACS Central Science, Vol 3, Iss 10, Pp 1078-1085 (2017)
Externí odkaz:
https://doaj.org/article/064ee2bb346f4e39b01e9493d1aace42
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Force-displacement (F-Z) curves are the most commonly used Atomic Force Microscopy (AFM) mode to measure the local, nanoscale elastic properties of soft materials like living cells. Yet a theoretical framework has been lacking that allows th
Externí odkaz:
https://doaj.org/article/45b8218a6d8d411c94cc58c9b938bda2
Autor:
Soumitra Ghosh, Robert L. Geahlen
Publikováno v:
EBioMedicine, Vol 2, Iss 11, Pp 1785-1798 (2015)
Microglial cells in the brains of Alzheimer's patients are known to be recruited to amyloid-beta (Aβ) plaques where they exhibit an activated phenotype, but are defective for plaque removal by phagocytosis. In this study, we show that microglia stre
Externí odkaz:
https://doaj.org/article/b6a2b89492f244c9bab58ee4d4962e02
Autor:
Mark L. Westbroek, Robert L. Geahlen
Publikováno v:
Antibodies, Vol 6, Iss 4, p 23 (2017)
Clustering of the B cell antigen receptor (BCR) by polyvalent antigens is transmitted through the SYK tyrosine kinase to the activation of multiple intracellular pathways that determine the physiological consequences of receptor engagement. To explor
Externí odkaz:
https://doaj.org/article/ba14d39132fb490592352f9f329cb091
Supplementary Figure S1 from Role of the Protein Tyrosine Kinase Syk in Regulating Cell-Cell Adhesion and Motility in Breast Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37981036598813184be6f424dea81b99
https://doi.org/10.1158/1541-7786.22519489
https://doi.org/10.1158/1541-7786.22519489
Supplementary Data from Role of the Protein Tyrosine Kinase Syk in Regulating Cell-Cell Adhesion and Motility in Breast Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16fe40679d0e8e910e19e5e2e60b323d
https://doi.org/10.1158/1541-7786.22519492
https://doi.org/10.1158/1541-7786.22519492
Autor:
Michael K. Wendt, Robert L. Geahlen, Casey J. Krusemark, Christopher D. Willey, Herbert Levine, Jun Wan, Sheng Liu, Jason T. George, Wells S. Brown, Ryan B. Khodadadi, Joshua C. Anderson, Wen-Hung Wang, Mohit Kumar Jolly, Saeed Salehin Akhand, Dongwook Kim, Shana D. Hardy, Aparna Shinde
The table lists the phosphorylation values for the array of peptides containing tyrosine or serine/threonine phosphorylation sites. This array was used to compare lysates from HME2 parental cells, TGF-beta-induced EMT and lapatinib-induced EMT.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439a0bd9328f99e1cd5b4282254d11f0
https://doi.org/10.1158/0008-5472.22423922.v1
https://doi.org/10.1158/0008-5472.22423922.v1
Autor:
Michael K. Wendt, Robert L. Geahlen, Casey J. Krusemark, Christopher D. Willey, Herbert Levine, Jun Wan, Sheng Liu, Jason T. George, Wells S. Brown, Ryan B. Khodadadi, Joshua C. Anderson, Wen-Hung Wang, Mohit Kumar Jolly, Saeed Salehin Akhand, Dongwook Kim, Shana D. Hardy, Aparna Shinde
The ability of breast cancer cells to transiently transition between epithelial and mesenchymal states contributes to their metastatic potential. Therefore, driving tumor cells into a stable mesenchymal state, as opposed to complete tumor cell eradic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08debc21e5bb4b38529f9a60a880bdad
https://doi.org/10.1158/0008-5472.c.6511613.v1
https://doi.org/10.1158/0008-5472.c.6511613.v1
Autor:
Michael K. Wendt, Robert L. Geahlen, Casey J. Krusemark, Christopher D. Willey, Herbert Levine, Jun Wan, Sheng Liu, Jason T. George, Wells S. Brown, Ryan B. Khodadadi, Joshua C. Anderson, Wen-Hung Wang, Mohit Kumar Jolly, Saeed Salehin Akhand, Dongwook Kim, Shana D. Hardy, Aparna Shinde
This file contain supplemental figures S1 through S4. These figures present additional immunoblot and replicate immune fluorescent frames to further support the conclusions made from the data presented in the main manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::073a791bbda683c102e22c6381dd9b1c
https://doi.org/10.1158/0008-5472.22423928
https://doi.org/10.1158/0008-5472.22423928
Publikováno v:
ImmunoHorizons. 3:254-261
The SYK protein-tyrosine kinase is a well-known mediator of signals elicited by the clustering of BCR complexes and other receptors that bear components that contain one or more ITAM sequences. Additional roles for the kinase in signaling through oth