Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Robert L. Eskay"'
Autor:
Mengdi Yao, Jenica D. Tapocik, Kejun Cheng, Estelle Barbier, Courtney E. King, Kenner C. Rice, Jesse R. Schank, Matthew Solomon, Markus Heilig, Robert L. Eskay, Hui Sun, Meghan E. Flanigan, Kelly E. Rowe, Camilla Karlsson, Ruslan Damadzic
Publikováno v:
Biological Psychiatry. 73:774-781
Background Genetic deletion or antagonism of the neurokinin 1 receptor (NK1R) decreases alcohol intake, alcohol reward, and stress-induced alcohol relapse in rodents, while TACR1 variation is associated with alcoholism in humans. Methods We used L822
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc4c717401920f3d415107abd46baec
https://doi.org/10.1016/j.biopsych.2012.12.027
https://doi.org/10.1016/j.biopsych.2012.12.027
Publikováno v:
Nutritional neuroscience. 3(3)
Neuropeptide Y (NPY), insulin, corticosterone (CORT) and 5-hydroxytryptamine (5-HT), or serotonin, are all involved in energy homeostasis. To show how they might interact, the effects of NPY on plasma insulin and on 5-HT metabolism in the paraventric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6aa88445cb7b0f723a071fe9348934
https://pubmed.ncbi.nlm.nih.gov/27414052
https://pubmed.ncbi.nlm.nih.gov/27414052
Autor:
Ruslan Damadzic, Carol Hamelink, Michael Brunnquell, Markus Heilig, Andrea Cippitelli, Annika Thorsell, Robert L. Eskay
Publikováno v:
Addiction Biology. 19:27-36
Excessive ethanol (EtOH) use leads to impaired memory and cognition. Using a rat model of binge-like intoxication, we tested whether elevated corticosterone (Cort) levels contribute to the neurotoxic consequences of EtOH exposure. Rats were adrenalec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95f2f3f70a362c1da018a1099777f580
https://doi.org/10.1111/j.1369-1600.2012.00451.x
https://doi.org/10.1111/j.1369-1600.2012.00451.x
Autor:
Michelle Zook, Robert L. Eskay, Andrea Cippitelli, Melanie L. Schwandt, Ruslan Damadzic, Markus Heilig, Lauren Bell
Publikováno v:
Neurobiology of Learning and Memory. 94:538-546
Excessive alcohol use leads to neurodegeneration in several brain structures including the hippocampal dentate gyrus and the entorhinal cortex. Cognitive deficits that result are among the most insidious and debilitating consequences of alcoholism. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1ff2a8d8a39f800739eeee0b74da79
https://doi.org/10.1016/j.nlm.2010.09.006
https://doi.org/10.1016/j.nlm.2010.09.006
Autor:
Markus Heilig, Vanessa Nieratschker, Elliott H. Margulies, Robert L. Eskay, Jessica Lidström, Stephen C. J. Parker, Hui Sun, Miklós Palkovits, Derek Passer, Ulrich S. Zimmermann, Manfred Laucht, Stephanie H. Witt, Wolfgang H. Sommer, Marcella Rietschel
Publikováno v:
Human Mutation. 31:E1594-E1608
Studies in humans and animals suggest a role for NPY in the mediation of behavioral stress responses. Here, we examined whether the NPY promoter variant rs16147:T>C is functional for expression of NPY in a brain region relevant for behavioral control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c582b40057d314f1b9b7cc0f2b5ae0
https://doi.org/10.1002/humu.21299
https://doi.org/10.1002/humu.21299
Autor:
Noel Southall, James Inglese, Robert L. Eskay, Wei Zheng, Christopher P. Austin, Steve Titus, Ke Liu, Paul Shinn, Markus Heilig
Publikováno v:
ASSAY and Drug Development Technologies. 8:362-374
Activation of Gq protein-coupled receptors can be monitored by measuring the increase in intracellular calcium with fluorescent dyes. Recent advances in fluorescent kinetic plate readers and liquid-handling technology have made it possible to follow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cbe74b9f3189775efccfb80842da215
https://doi.org/10.1089/adt.2009.0245
https://doi.org/10.1089/adt.2009.0245
Autor:
Robert L. Eskay, Hui Sun, Loren H. Parsons, Daniel W. Hommer, David T. George, Francisco Javier Pavón, Wojciech Margas, Michael Schoor, Wolfgang H. Sommer, Annika Thorsell, Melanie L. Schwandt, Markus Heilig, Victor Ruiz-Velasco, Peter Herscovitch, Ruslan Damadzic, John C. Umhau, Vijay A. Ramchandani
Publikováno v:
Molecular psychiatry
Excessive alcohol use, a major cause of morbidity and mortality, is less well understood than other addictive disorders. Dopamine release in ventral striatum is a common element of drug reward, but alcohol has an unusually complex pharmacology, and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da3a1e50e31006a09ffdbc9adfb42330
http://europepmc.org/articles/PMC2925052
http://europepmc.org/articles/PMC2925052
Autor:
Kimberly Nixon, Fulton T. Crews, Markus Heilig, Robert L. Eskay, Wolfgang H. Sommer, Anita C. Hansson, Ruslan Damadzic, Roberto Rimondini
Publikováno v:
The International Journal of Neuropsychopharmacology. 13:583-593
Alcohol dependence leads to persistent neuroadaptations, potentially related to structural plasticity. Previous work has shown that hippocampal neurogenesis is modulated by alcohol, but effects of chronic alcohol on neurogenesis in the forebrain subv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4cbfccb25341d520f39b3542b1c0b6
https://doi.org/10.1017/s1461145710000246
https://doi.org/10.1017/s1461145710000246
