Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Robert L. Dorit"'
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32456 (2012)
Bacterial RNase P is an essential ribonucleoprotein composed of a catalytic RNA component (encoded by the rnpB gene) and an associated protein moiety (encoded by rnpA). We construct a system that allows for the deletion of the essential endogenous rn
Externí odkaz:
https://doaj.org/article/5f1cdc2354414236b1752fe95219c7e3
Publikováno v:
Journal of Colloid and Interface Science. 519:203-213
Hypothesis: The nucleation of biofilms is known to be affected by both the chemistry and topography of the underlying substrate, particularly when topography includes nanoscale (
Autor:
Michelle Lizotte-Waniewski, Jocelyn Rice, Paula C. G. Turrini, Jasmine Lopez Loveland, Robert L. Dorit
Publikováno v:
Journal of Molecular Evolution. 79:143-152
While critical cellular components-such as the RNA moiety of bacterial ribonuclease P-can sometimes be replaced with a highly divergent homolog, the cellular response to such perturbations is often unexpectedly complex. RNase P is a ubiquitous and es
Publikováno v:
Future Medicinal Chemistry. 5:1231-1242
The importance of the human microbiome in health may be the single most valuable development in our conception of the microbial world since Pasteur’s germ theory of the 1860s. Its implications for our understanding of health and pathogenesis are pr
Publikováno v:
The Bacteriocins: Current Knowledge and Future Prospects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2473fb12c148cecfbd858211bba0206
https://doi.org/10.21775/9781910190371.08
https://doi.org/10.21775/9781910190371.08
Autor:
Vivian Liu, Robert L. Dorit, Morgan Dennis, Christopher M. Roy, Sandra M. Robinson, Margaret A. Riley
Publikováno v:
Biochemical Society Transactions. 40:1438-1442
Pathogenic bacteria resistant to many or all antibiotics already exist. With the decline in microbiological research at pharmaceutical companies, the high rate at which resistance has evolved and spread has demanded a novel approach to addressing thi
Autor:
Robert L. Dorit, Margaret A. Riley
Publikováno v:
Journal of Molecular Evolution. 55:347-355
In an effort to develop derivatives of the Escherichia coli antimicrobial protein colicin E9 that exhibit novel interactions with a target cell, we mutagenized a 10-amino acid region located at the C terminus of the colicin receptor-binding domain. W
Autor:
Kyle B. Cole, Robert L. Dorit
Publikováno v:
Journal of Molecular Biology. 307:1181-1193
Escherichia coli RNase P derivatives were evolved in vitro for DNA cleavage activity. Ribonucleoproteins sampled after ten generations of selection show a >400-fold increase in the first-order rate constant ( k cat ) on a DNA substrate, reflecting a
Autor:
Anne Ridley, Serge Roche, Giulio Superti-Furga, Rein Aasland, Robert OJ Weinzierl, Elisa Izaurralde, Elisabeth Dawson, Mike Jones, Eric A Miska, Laurent Kodjabachian, Robert L Dorit
Publikováno v:
Current Opinion in Genetics & Development. 9:485-494
Autor:
Klaus Schugart, Diko Becker, Amos S. Deinard, Carmela M. Castiglione, Robert L. Dorit, Kenneth K. Kidd, Zhiling Jiang, Frank H. Ruddle
Publikováno v:
Journal of Experimental Zoology. 285:170-176
This study reports the results of a comparative sequencing study in higher primates, focusing on the intergenic region located between HOXB6 and HOXB7. We have examined an 832 bp. region, encompassing a putative Lateral Plate Mesoderm (LPM) enhancer