Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Robert L. Conhaim"'
Publikováno v:
Pulmonary Circulation, Vol 8 (2018)
We compared acinar perfusion in isolated rat lungs ventilated using positive or negative pressures. The lungs were ventilated with air at transpulmomary pressures of 15/5 cm H 2 O, at 25 breaths/min, and perfused with a hetastarch solution at P pulm
Externí odkaz:
https://doaj.org/article/10465cb6311d4cea9912fe4c983d8fa4
Publikováno v:
Microvascular Research. 122:71-77
Pulmonary alveolar septal capillaries receive their perfusion from a web of larger surrounding acinar vessels. Using 4 μm diam. Latex particles, we showed that positive pressure ventilation narrowed the acinar vessels as evidenced by venous 4 μm pa
Publikováno v:
Physiological Reports
Obstructive sleep apnea is associated with significant cardiovascular disease, yet little is known about the effects of OSA on pulmonary microvascular perfusion. In a recent report, we showed that pulmonary microvascular perfusion was significantly m
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 316(1)
Obstructive sleep apnea (OSA) is associated with significant cardiovascular consequences, including pulmonary hypertension, yet little is known about its effects on pulmonary microvascular perfusion. To investigate effects of OSA on pulmonary microva
Publikováno v:
Pulmonary Circulation
Pulmonary Circulation, Vol 8 (2018)
Pulmonary Circulation, Vol 8 (2018)
We compared acinar perfusion in isolated rat lungs ventilated using positive or negative pressures. The lungs were ventilated with air at transpulmomary pressures of 15/5 cm H 2 O, at 25 breaths/min, and perfused with a hetastarch solution at P pulm
Publikováno v:
Shock. 41:528-536
We showed previously that a 30% blood loss in rats, without resuscitation, caused significant accumulation of microthrombi and leukocytes within the pulmonary circulation by 24 h. We hypothesized that the microthrombi formed spontaneously as a conseq
Autor:
David F. Pegelow, Marlowe W. Eldridge, Alyssa Drezdon, Brendan R. Fulmer, Robert L. Conhaim, Melissa L. Bates, Emily T. Farrell
Publikováno v:
Journal of Applied Physiology. 112:1915-1920
Intrapulmonary arteriovenous anastomoses (IPAVS) directly connect the arterial and venous circulations in the lung, bypassing the capillary network. Here, we used solid, latex microspheres and isolated rat lung and intact, spontaneously breathing rat
Publikováno v:
Journal of Applied Physiology. 112:48-53
Vasoconstrictors cause contraction of pulmonary microvascular endothelial cells in culture. We wondered if this meant that contraction of these cells in situ caused active control of microvascular perfusion. If true, it would mean that pulmonary micr
Publikováno v:
The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology. 294:550-557
To assess the effects of intra-abdominal bacteremia on lung cellular function in vivo, we used electron microscopy to quantify the uptake of 6 nm diameter, albumin-coated colloidal gold particles (overall diam. 20.8 nm) by cells in the lungs of rats
Autor:
Bruce A. Harms, Karri A. Kluesner, Alejandro Munoz-del-Rio, Kal E. Watson, Dennis M. Heisey, Robert L. Conhaim
Publikováno v:
Shock. 29:410-416
Acute hemorrhage is often followed by devastating lung injury. However, why blood loss should lead to lung injury is not known. One possibility is that hemorrhage rapidly disturbs the distribution of microvascular perfusion at the alveolar level, whi