Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Robert L. Caldwell"'
Autor:
Rebecca Y Wang, Jason V. Rogers, Maria Ingaramo, R. Scott McIsaac, Alisha G Lewis, Ilya Soifer, Patrick A. Gibney, David G. Hendrickson, Robert L. Caldwell, David Botstein
Publikováno v:
Molecular Biology of the Cell. 32
The electron transport chain (ETC) is a well-studied and highly conserved metabolic pathway that produces ATP through generation of a proton gradient across the inner mitochondrial membrane coupled to oxidative phosphorylation. ETC mutations are asso
Autor:
Richard M. Caprioli, Susan R. Opalenik, Robert L. Caldwell, Lillian B. Nanney, Jeffrey M. Davidson
Publikováno v:
Wound Repair and Regeneration. 16:442-449
MRL/MpJ-Fas(lpr) mice exhibit the ability to regenerate ear tissue excised by dermal punches. This is an exceptional model to identify candidate proteins that may regulate regeneration in typically nonregenerative tissues. Identification of key molec
Autor:
Josiane E. Eid, Andrea L. Frump, Roy Barco, Christina B. Garcia, Andrew E. Benesh, Laura B. Hunt, Robert L. Caldwell
Publikováno v:
Molecular Biology of the Cell. 18:4003-4012
Synovial sarcoma is a soft tissue cancer associated with a recurrent t(X:18) translocation that generates one of two fusion proteins, SYT-SSX1 or SYT-SSX2. In this study, we demonstrate that SYT-SSX2 is a unique oncogene. Rather than confer enhanced
Autor:
Jeffrey M. Davidson, Susan R. Opalenik, Alonda C. Pollins, Lillian B. Nanney, Nancy L. Cardwell, Robert L. Caldwell
Publikováno v:
Journal of Investigative Dermatology Symposium Proceedings. 11(1):132-139
Mechanisms that drive wound repair are complex and have challenged wound-healing investigators for many years. In this review, we present four examples of new tools that are being utilized to discover events that drive wound repair and regeneration.
HIV-1 TAT represses transcription of the bone morphogenic protein receptor-2 in U937 monocytic cells
Publikováno v:
Journal of Leukocyte Biology. 79:192-201
The bone morphogenetic protein receptor-2 (BMPR2) is a member of the transforming growth factor-β receptor family and is expressed on the surface of several cell type including endothelial cells and macrophages. Recently, a cause for familial primar
Publikováno v:
Molecular & Cellular Proteomics. 4:394-401
Matrix-assisted laser desorption ionization mass spectrometry (MALDI MS) has become a valuable tool to address a broad range of questions in many areas of biomedical research. One such application allows spectra to be obtained directly from intact ti
Publikováno v:
Clinical orthopaedics and related research. 450
UNLABELLED Proteomics is the emerging technology that evaluates normal and abnormal protein expression in tissues. Tissue profiling by matrix assisted laser desorption ionization mass spectrometry (MALDI MS) is a proteomic tool that permits the rapid
Publikováno v:
Archives of biochemistry and biophysics. 449(1-2)
Macrophage transcription is significantly altered by HIV-1 infection. HIV Tat, an immediate-early product of the viral lifecycle, interacts with host transcription factors to alter host gene expression. We have previously shown that Tat represses tra
Publikováno v:
Cancer genomicsproteomics. 2(6)
Soft tissue sarcomas are rare, heterogeneous, mesenchymal tumors that have been poorly classified. The heterogeneity of these aggressive tumors has made consistent tumor grading difficult and accurately predicting the behavior of the tumor based on t
Publikováno v:
Molecularcellular proteomics : MCP. 4(4)
Matrix-assisted laser desorption ionization mass spectrometry (MALDI MS) has become a valuable tool to address a broad range of questions in many areas of biomedical research. One such application allows spectra to be obtained directly from intact ti