Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Robert L Unckless"'
Autor:
Jessamyn I Perlmutter, Joanne R Chapman, Mason C Wilkinson, Isaac Nevarez-Saenz, Robert L Unckless
Publikováno v:
PLoS Genetics, Vol 20, Iss 3, p e1011155 (2024)
Antimicrobial peptides (AMPs) are at the interface of interactions between hosts and microbes and are therefore expected to be rapidly evolving in a coevolutionary arms race with pathogens. In contrast, previous work demonstrated that insect AMPs ten
Externí odkaz:
https://doaj.org/article/23ff312ea92f4f8f934e01f14f099829
Publikováno v:
PLoS Pathogens, Vol 19, Iss 8, p e1010934 (2023)
The genetic causes of phenotypic variation often differ depending on the population examined, particularly if the populations were founded by relatively small numbers of genotypes. Similarly, the genetic causes of phenotypic variation among similar t
Externí odkaz:
https://doaj.org/article/52a6aa64856a4112999a822a8ebc9c15
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 4 (2021)
AbstractProteins involved in post-copulatory interactions between males and females are among the fastest evolving genes in many species, usually attributed to their involvement in reproductive conflict. As a result, these proteins are thought to oft
Externí odkaz:
https://doaj.org/article/1206a2e382fb489e919a0b80f48535ca
Autor:
Tom Hill, Robert L Unckless
Publikováno v:
eLife, Vol 9 (2020)
Hosts and viruses are constantly evolving in response to each other: as a host attempts to suppress a virus, the virus attempts to evade and suppress the host’s immune system. Here, we describe the recurrent evolution of a virulent strain of a DNA
Externí odkaz:
https://doaj.org/article/a323e83f6ca944e29bea41fbe0eb2c87
Autor:
María Angélica Bravo Núñez, Ibrahim M Sabbarini, Lauren E Eide, Robert L Unckless, Sarah E Zanders
Publikováno v:
eLife, Vol 9 (2020)
Killer meiotic drivers are genetic parasites that destroy ‘sibling’ gametes lacking the driver allele. The fitness costs of drive can lead to selection of unlinked suppressors. This suppression could involve evolutionary tradeoffs that compromise
Externí odkaz:
https://doaj.org/article/fe893d4b514a4c8aa858dad961d76f5e
Autor:
Jessamyn I Perlmutter, Sarah R Bordenstein, Robert L Unckless, Daniel P LePage, Jason A Metcalf, Tom Hill, Julien Martinez, Francis M Jiggins, Seth R Bordenstein
Publikováno v:
PLoS Pathogens, Vol 15, Iss 9, p e1007936 (2019)
Wolbachia are the most widespread maternally-transmitted bacteria in the animal kingdom. Their global spread in arthropods and varied impacts on animal physiology, evolution, and vector control are in part due to parasitic drive systems that enhance
Externí odkaz:
https://doaj.org/article/377e739c26ae45a69f479690e2d6b034
Autor:
Elizabeth ML Duxbury, Jonathan P Day, Davide Maria Vespasiani, Yannik Thüringer, Ignacio Tolosana, Sophia CL Smith, Lucia Tagliaferri, Altug Kamacioglu, Imogen Lindsley, Luca Love, Robert L Unckless, Francis M Jiggins, Ben Longdon
Publikováno v:
eLife, Vol 8 (2019)
It is common to find considerable genetic variation in susceptibility to infection in natural populations. We have investigated whether natural selection increases this variation by testing whether host populations show more genetic variation in susc
Externí odkaz:
https://doaj.org/article/624025c10f434438a89a90bb98bd816b
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005030 (2015)
Both malnutrition and undernutrition can lead to compromised immune defense in a diversity of animals, and "nutritional immunology" has been suggested as a means of understanding immunity and determining strategies for fighting infection. The genetic
Externí odkaz:
https://doaj.org/article/2a42e17a7d194c1fb8ce78c93bfe70aa
Autor:
H Allen Orr, Robert L Unckless
Publikováno v:
PLoS Genetics, Vol 10, Iss 8, p e1004551 (2014)
Evolutionary rescue occurs when a population that is threatened with extinction by an environmental change adapts to the change sufficiently rapidly to survive. Here we extend the mathematical theory of evolutionary rescue. In particular, we model ev
Externí odkaz:
https://doaj.org/article/106d49fc2d364a6c9777fea298f2a501
Autor:
Robert L Unckless
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26564 (2011)
Little is known about the viruses infecting most species. Even in groups as well-studied as Drosophila, only a handful of viruses have been well-characterized. A viral metagenomic approach was used to explore viral diversity in 83 wild-caught Drosoph
Externí odkaz:
https://doaj.org/article/35ae5724a6974cb38086f8279a45f531