Výsledky vyhledávání - "Robert L Griffith"

Implication of Specific DQB1 Alleles in Genetic Susceptibility and Resistance by Identification of IDDM Siblings With Novel HLA-DQB1 Allele and Unusual DR2 and DR1 Haplotypes

Autor: Robert L Griffith, Ralph Ziegler, Teodorica L. Bugawan, Henry A. Erlich, Chester A. Alper, George S. Eisenbarth

Publikováno v: Diabetes. 40:478-481

Genetic susceptibility to insulin-dependent diabetes mellitus (IDDM) is associated with the HLA-DR3 and DR4 haplotypes. The HLA-DR2 haplotype is negatively associated with IDDM, an association that has been interpreted as dominant protection. Here, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f127e46bcaf095c7be05f88a83bcdbcb
https://doi.org/10.2337/diab.40.4.478

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DNA amplification for DQ typing as an adjunct to serological prenatal HLA typing for the identification of potential donors for umbilical cord blood transplantation

Autor: Hal E. Broxmeyer, Marilyn S. Pollack, Akila Zaafran, Robert L. Griffith, Henry A. Erlich, Arleen D. Auerbach

Publikováno v: Human Immunology. 30:45-49

It has recently been demonstrated that umbilical cord blood from genotypically human leukocyte antigen (HLA)-matched donors can provide sufficient numbers of progenitor cells for hematopoietic reconstitution. This technique has been successfully appl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7297cccec6a1841bff48dd7c52777b4
https://doi.org/10.1016/0198-8859(91)90070-p

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Rapid typing of DNA sequence polymorphism at the HLA-DRB1 locus using the polymerase chain reaction and nonradioactive oligonucleotide probes

Autor: Robert L. Griffith, Henry A. Erlich, Stephen J. Scharf

Publikováno v: Human Immunology. 30:190-201

An HLA-DR typing system that uses sequence-specific oligonucleotide (SSO) probes conjugated to horseradish peroxidase (HRP) for analyzing DRB alleles amplified by the polymerase chain reaction has been developed. Using 25 HRP-SSO probes and two prime

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79720dca84d0453f0bf800af37cf8bb
https://doi.org/10.1016/0198-8859(91)90034-7

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HLA-DQβ Sequence Polymorphism and Genetic Susceptibility to IDDM

Autor: Brian Tait, Henry A. Erlich, Robert L Griffith, Gerald T. Nepom, Stephen Joel Scharf, Teodorica Bugawan

Publikováno v: Diabetes. 39:96-103

The analysis of HLA-DQ beta nucleotide sequence polymorphism in insulin-dependent diabetes mellitus (IDDM) patients and control subjects suggests a role for the DQ beta-chain in genetic susceptibility. Sequence determination and oligonucleotide hybri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e70e07f0da7fbf652f8740e523a7a343
https://doi.org/10.2337/diacare.39.1.96

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HLA-DR, DQ and DP typing using PCR amplification and immobilized probes

Autor: P.S. Walsh, Teodorica L. Bugawan, Henry A. Erlich, Ann B Begovich, Robert L. Griffith, Randall K. Saiki, Stephen J. Scharf, Russell Higuchi

Publikováno v: European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics. 18(1-2)

A simple, rapid, and precise method of typing HLA class II polymorphism would be valuable in the areas of disease susceptibility, tissue transplantation, individual identification and anthropological genetics. Here we describe a method of analysing c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569cf8337c46cbc17e48cd57c217e1b5
https://pubmed.ncbi.nlm.nih.gov/2069944

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Unique sequences for two HLA-DRB1 genes expressed on distinct DRw6 haplotypes

Autor: Robert L. Griffith, John A. Hansen, Henry A. Erlich, B. Nisperos, Anajane G. Smith, Effie W. Petersdorf, Eric Mickelson, Paul J. Martin

Publikováno v: Immunogenetics. 32

We have used restriction fragment length polymorphism (RFLP) analysis and DNA sequencing to characterize two distinct DRB1 alleles expressed on DRw52 and DQw7-associated haplotypes but not readily defined by conventional DR serology. These two haplot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1103d99ab98f28c8eab014b8dabd1c0
https://doi.org/10.1007/bf00210446

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Three principles of representation for semantic networks

Autor: Robert L Griffith

Publikováno v: ACM Transactions on Database Systems. 7:417-442

Semantic networks are so intuitive and easy to use that they are often employed without much thought as to the phenomenon of semantic nets themselves. Since they are becoming more and more a tool of artificial intelligence and now database technology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e37def54db910ede97a350942bf343b3
https://doi.org/10.1145/319732.319743

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Lipoid pneumonia due to prolonged ingestion of mineral oil

Autor: Robert L. Griffith, John B. Meyers

Publikováno v: Diseases of the chest. 27(6)

1. Seven cases of lipoid pneumonia found at postmortem examination are presented. These represent 2 per cent of the postmortem examinations at this hospital for a three-year period. All of the cases had other serious illnesses but in at least four, l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ead3cf96c31ff1f2650a6c4ac61212
https://pubmed.ncbi.nlm.nih.gov/14380105

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