Zobrazeno 1 - 10 of 246 pro vyhledávání: '"Robert L, Danner"'
1
Akademický článek
In a Canine Model of Septic Shock, Cardiomyopathy Occurs Independent of Catecholamine Surges and Cardiac Microvascular Ischemia
Autor: Verity J. Ford, Willard N. Applefeld, Jeffrey Wang, Junfeng Sun, Steven B. Solomon, Harvey G. Klein, Jing Feng, Juan Lertora, Parizad Parizi‐Torabi, Robert L. Danner, Michael A. Solomon, Marcus Y. Chen, Charles Natanson
Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 15 (2024)
Background High levels of catecholamines are cardiotoxic and associated with stress‐induced cardiomyopathies. Using a septic shock model that reproduces the reversible cardiomyopathy seen over 10 days associated with human septic shock, we investig
Externí odkaz: https://doaj.org/article/a57db40968374e55a6dd3757f6f640fe
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2
Akademický článek
Cardiac Magnetic Resonance Studies in a Large Animal Model That Simulates the Cardiac Abnormalities of Human Septic Shock
Autor: Verity J. Ford, Willard N. Applefeld, Jeffrey Wang, Junfeng Sun, Steven B. Solomon, Stanislav Sidenko, Jing Feng, Cynthia Sheffield, Harvey G. Klein, Zu‐Xi Yu, Parizad Torabi‐Parizi, Robert L. Danner, Vandana Sachdev, Michael A. Solomon, Marcus Y. Chen, Charles Natanson
Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 15 (2024)
Background Septic shock is associated with increases in end‐diastolic volume (EDV) and decreases in ejection fraction that reverse within 10 days. Nonsurvivors do not develop EDV increases. The mechanism is unknown. Methods and Results Purpose‐br
Externí odkaz: https://doaj.org/article/af495b8bb43042a29f124e2468971206
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3
Inflammation and DKK1-induced AKT activation contribute to endothelial dysfunction following NR2F2 loss
Autor: Edward J. Dougherty, Li-Yuan Chen, Keytam S. Awad, Gabriela A. Ferreyra, Cumhur Y. Demirkale, Ali Keshavarz, Salina Gairhe, Kathryn A. Johnston, Madelyn E. Hicks, Alexis B. Sandler, Colleen S. Curran, Janell M. Krack, Yi Ding, Anthony F. Suffredini, Michael A. Solomon, Jason M. Elinoff, Robert L. Danner
Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L783-L798
NR2F2 loss in the endothelial lining of blood vessels is associated with cardiovascular disease. Here, NR2F2-silenced human endothelial cells were inflammatory, proliferative, hypermigratory, and apoptosis-resistant with increased oxidant stress and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0fe854373f3036ca142f6dd2ac9a844f
https://doi.org/10.1152/ajplung.00171.2022
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5
Data from Eradication of Solid Human Breast Tumors in Nude Mice with an Intravenously Injected Light-Emitting Oncolytic Vaccinia Virus
Autor: Aladar A. Szalay, Francesco M. Marincola, Peter J. Munson, Robert L. Danner, Nanhai Chen, Ena Wang, Yong A. Yu, Qian Zhang
Previously, we reported that a recombinant vaccinia virus (VACV) carrying a light-emitting fusion gene enters, replicates in, and reveals the locations of tumors in mice. A new recombinant VACV, GLV-1h68, as a simultaneous diagnostic and therapeutic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04489632114d7450d66aa4f88a96bf1b
https://doi.org/10.1158/0008-5472.c.6496464.v1
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8
Suspected Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) Reinfections: Incidence, Predictors, and Healthcare Use Among Patients at 238 US Healthcare Facilities, 1 June 2020 to 28 February 2021
Autor: Deblina Datta, Alexander Lawandi, Michael Klompas, Sameer S Kadri, Cumhur Y Demirkale, Junfeng Sun, Aaron M. Harris, Robert L. Danner, Pavithra Natarajan, Adi V. Gundlapalli, Sarah Warner, Sapna Bamrah Morris
Publikováno v: Clinical Infectious Diseases. 74:1489-1492
In a retrospective cohort study, among 131 773 patients with previous coronavirus disease 2019 (COVID-19), reinfection with severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) was suspected in 253 patients (0.2%) at 238 US healthcare facilit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99f4e63f44255baa8e900f0b1fe6f272
https://doi.org/10.1093/cid/ciab671
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9
Comparative effectiveness research in critically ill patients: risks associated with mischaracterising usual care
Autor: Willard N. Applefeld, Charles Natanson, Robert L. Danner, Peter Q. Eichacker, Harvey G. Klein, Jeffrey Wang
Publikováno v: Critical Care and Resuscitation. 22:110-118
Comparative effectiveness research can help guide the use of common, routine medical practices. However, to be safe and informative, such trials must include at least one treatment arm that accurately portrays current practices. While comparative eff
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e64b3de5242e1c375aa744d6790170e
https://doi.org/10.51893/2020.2.r1
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10
Pharmacoepidemiology of Ceftazidime-Avibactam Use: A Retrospective Cohort Analysis of 210 US Hospitals
Autor: Cumhur Y Demirkale, John P. Dekker, Jennifer Adjemian, Sameer S Kadri, Roland A. Matsouaka, Christopher W. Woods, Jeffrey R Strich, Yi Ling Lai, Michael Klompas, Robert L. Danner, Tara N. Palmore, Emily Ricotta, John H. Powers, Chanu Rhee, Sarah Warner, Samuel F. Hohmann
Publikováno v: Clinical Infectious Diseases. 72:611-621
Background Ceftazidime-avibactam has in vitro activity against some carbapenem-resistant gram-negative infections (GNIs), and therefore may be a useful alternative to more toxic antibiotics such as colistin. Understanding ceftazidime-avibactam uptake
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::478607494ffaa7af09727595ad7945a0
https://doi.org/10.1093/cid/ciaa061
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