Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Robert Krautz"'
Autor:
Signe Schmidt Kjølner Hansen, Robert Krautz, Daria Rago, Jesper Havelund, Arnaud Stigliani, Nils J. Færgeman, Audrey Prézelin, Julie Rivière, Anne Couturier-Tarrade, Vyacheslav Akimov, Blagoy Blagoev, Betina Elfving, Ditte Neess, Ulla Vogel, Konstantin Khodosevich, Karin Sørig Hougaard, Albin Sandelin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract The fetal development of organs and functions is vulnerable to perturbation by maternal inflammation which may increase susceptibility to disorders after birth. Because it is not well understood how the placenta and fetus respond to acute lu
Externí odkaz:
https://doaj.org/article/f27ea51dbf684c569e6842c66b46c497
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 7, Pp n/a-n/a (2023)
Abstract Many genes are co‐expressed and form genomic domains of coordinated gene activity. However, the regulatory determinants of domain co‐activity remain unclear. Here, we leverage human individual variation in gene expression to characterize
Externí odkaz:
https://doaj.org/article/c0ff0e72b3834be1a2a4a6dc42af6a37
Autor:
Jelle van den Ameele, Robert Krautz, Seth W. Cheetham, Alex P. A. Donovan, Oriol Llorà-Batlle, Rebecca Yakob, Andrea H. Brand
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Notch signalling plays a key role in cell fate transitions, but how Notch activates distinct regulatory networks in closely related cell types is not well understood. Here the authors profile Notch and RBPJ targets in the developing mouse cortex and
Externí odkaz:
https://doaj.org/article/93dff00102e946c68df70fd26447e0de
Autor:
Jocelyn L.Y. Tang, Robert Krautz, Oriol Llorà-Batlle, Anna E. Hakes, Paul M. Fox, Andrea H. Brand
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101788- (2022)
Summary: NanoDam is a technique for genome-wide profiling of the binding targets of any endogenously tagged chromatin-binding protein in vivo, without the need for antibodies, crosslinking, or immunoprecipitation. Here, we explain the procedure for N
Externí odkaz:
https://doaj.org/article/72b0855f41e54215b2bc2a9c33b41fcb
Publikováno v:
eLife, Vol 9 (2020)
Postmitotic tissues are incapable of replacing damaged cells through proliferation, but need to rely on buffering mechanisms to prevent tissue disintegration. By constitutively activating the Ras/MAPK-pathway via RasV12-overexpression in the postmito
Externí odkaz:
https://doaj.org/article/9a2a7442136b4d7b82958437a96541b2
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 7, Pp 2139-2149 (2017)
Many leukemia patients suffer from dysregulation of their immune system, making them more susceptible to infections and leading to general weakening (cachexia). Both adaptive and innate immunity are affected. The fruit fly Drosophila melanogaster has
Externí odkaz:
https://doaj.org/article/be810cc02b4c4a5fb9c90944be0bf743
Autor:
Alexis Dziedziech, Martin Schmid, Badrul Arefin, Thomas Kienzle, Robert Krautz, Ulrich Theopold
Publikováno v:
Data in Brief, Vol 25, Iss , Pp - (2019)
Insect hemolymph coagulation: Kinetics of classically and non-classically secreted clotting factors Schmid et al., 2019. The linked article demonstrates the localization of two secretory proteins in Drosophila melanogaster, Prophenoloxidase (PPO2) an
Externí odkaz:
https://doaj.org/article/3d6c7c5b76764d2aaf49f8b5b8808a07
Autor:
Thomas Hauling, Robert Krautz, Robert Markus, Anne Volkenhoff, Lucie Kucerova, Ulrich Theopold
Publikováno v:
Biology Open, Vol 3, Iss 4, Pp 250-260 (2014)
Our goal is to characterize the innate immune response against the early stage of tumor development. For this, animal models where genetic changes in specific cells and tissues can be performed in a controlled way have become increasingly important,
Externí odkaz:
https://doaj.org/article/4c71bd9a01374bc9879bb9d8008ba512
Autor:
Badrul Arefin, Lucie Kucerova, Robert Krautz, Holger Kranenburg, Farjana Parvin, Ulrich Theopold
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136593 (2015)
Apart from their role in cellular immunity via phagocytosis and encapsulation, Drosophila hemocytes release soluble factors such as antimicrobial peptides, and cytokines to induce humoral responses. In addition, they participate in coagulation and wo
Externí odkaz:
https://doaj.org/article/b8253162cb5a462d8e7f4cbba2da3dbc
Autor:
Signe Schmidt Kjølner Hansen, Robert Krautz, Daria Rago, Jesper Havelund, Nils J. Færgeman, Audrey Prézelin, Julie Rivière, Anne Couturier-Tarrade, Vyacheslav Akimov, Blagoy Blagoev, Betina Elfving, Arnaud Stigliani, Ulla Birgitte Vogel, Konstantin Khodosevich, Karin Sørig Hougaard, Albin Sandelin
Maternal immune system activation (MIA) during pregnancy can disrupt the fetal environment, causing postnatal susceptibility to disorders. How the placenta and the fetus respond to acute MIA over time is unknown. Here, we characterized the response t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6492259e1052fbd35457071fad0f91a2
https://doi.org/10.1101/2023.03.17.532052
https://doi.org/10.1101/2023.03.17.532052