Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Robert Koesters"'
Autor:
Shaman Narayanasamy, Varvara Markina, Adrian Thorogood, Adriana Blazkova, Mahsa Shabani, Bartha M. Knoppers, Barbara Prainsack, Robert Koesters
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Whole genome/exome sequencing (WGS/WES) has become widely adopted in research and, more recently, in clinical settings. Many hope that the information obtained from the interpretation of these data will have medical benefits for patients and—in som
Externí odkaz:
https://doaj.org/article/ed411e6569c4482d8dd868c140c8534a
Autor:
Matthias B Moor, Suresh K Ramakrishnan, Finola Legrand, Matthias Bachtler, Robert Koesters, Nancy E Hynes, Andreas Pasch, Olivier Bonny
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236361 (2020)
MEdiator of cell MOtility1 (MEMO1) is a ubiquitously expressed redox protein involved in extracellular ligand-induced cell signaling. We previously reported that inducible whole-body Memo1 KO (cKO) mice displayed a syndrome of premature aging and dis
Externí odkaz:
https://doaj.org/article/28a45783d20d45189c9dccd7963e0f8f
Autor:
Jérémie Canonica, Simona Frateschi, Emilie Boscardin, Anna Ebering, Chloé Sergi, Yannick Jäger, Thibaud Peyrollaz, Anne-Marie Mérillat, Marc Maillard, Petra Klusonova, Alex Odermatt, Robert Koesters, Anne Debonneville, Olivier Staub, Sophia N. Verouti, Edith Hummler
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Chronic glucocorticoid infusion impairs NCC activity and induces a non-dipping profile in mice, suggesting that glucocorticoids are essential for daily blood pressure variations. In this paper, we studied mice lacking the renal tubular glucocorticoid
Externí odkaz:
https://doaj.org/article/94cec7ac22974ea5b7e7c6c28a09bae4
Autor:
Matthias B. Moor, Barbara Haenzi, Finola Legrand, Robert Koesters, Nancy E. Hynes, Olivier Bonny
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Ablation of the Mediator of ErbB2-driven Cell Motility 1 (Memo1) in mice altered calcium homeostasis and renal calcium transporter abundance by an unknown mechanism. Here, we investigated the role of intrarenal Memo in renal calcium handling. We have
Externí odkaz:
https://doaj.org/article/77139af41fe94aa58d899136b0a2998c
Autor:
Olivier Bonny, Matthias Bachtler, Finola Legrand, Nancy E. Hynes, Andreas Pasch, Matthias B. Moor, Suresh K. Ramakrishnan, Robert Koesters
Publikováno v:
PLoS ONE
Moor, Matthias B.; Ramakrishnan, Suresh K; Legrand, Finola; Bachtler, Matthias; Koesters, Robert; Hynes, Nancy E; Pasch, Andreas; Bonny, Olivier (2020). Elevated serum magnesium lowers calcification propensity in Memo1-deficient mice. PLoS ONE, 15(7), e0236361. Public Library of Science 10.1371/journal.pone.0236361
PLOS ONE, vol. 15, no. 7, pp. e0236361
PLoS ONE, Vol 15, Iss 7, p e0236361 (2020)
Moor, Matthias B.; Ramakrishnan, Suresh K; Legrand, Finola; Bachtler, Matthias; Koesters, Robert; Hynes, Nancy E; Pasch, Andreas; Bonny, Olivier (2020). Elevated serum magnesium lowers calcification propensity in Memo1-deficient mice. PLoS ONE, 15(7), e0236361. Public Library of Science 10.1371/journal.pone.0236361
PLOS ONE, vol. 15, no. 7, pp. e0236361
PLoS ONE, Vol 15, Iss 7, p e0236361 (2020)
MEdiator of cell MOtility1 (MEMO1) is a ubiquitously expressed redox protein involved in extracellular ligand-induced cell signaling. We previously reported that inducible whole-body Memo1 KO (cKO) mice displayed a syndrome of premature aging and dis
Autor:
Ruth E Schietke, Thomas Hackenbeck, Maxine Tran, Regina Günther, Bernd Klanke, Christina L Warnecke, Karl X Knaup, Deepa Shukla, Christian Rosenberger, Robert Koesters, Sebastian Bachmann, Peter Betz, Gunnar Schley, Johannes Schödel, Carsten Willam, Thomas Winkler, Kerstin Amann, Kai-Uwe Eckardt, Patrick Maxwell, Michael S Wiesener
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e31034 (2012)
The Hypoxia-inducible transcription Factor (HIF) represents an important adaptive mechanism under hypoxia, whereas sustained activation may also have deleterious effects. HIF activity is determined by the oxygen regulated α-subunits HIF-1α or HIF-2
Externí odkaz:
https://doaj.org/article/cf57eedd2a284375914bfd92fcd3be7f
Autor:
Romain Perrier, Emilie Boscardin, Marc Maillard, Johannes Loffing, Robert Koesters, Dominique Loffing-Cueni, Chloé Sergi, Edith Hummler, Bernard C. Rossier
Publikováno v:
Journal of the American Society of Nephrology. 29:977-990
The amiloride-sensitive epithelial sodium channel (ENaC) and the thiazide-sensitive sodium chloride cotransporter (NCC) are key regulators of sodium and potassium and colocalize in the late distal convoluted tubule of the kidney. Loss of the αENaC s
Publikováno v:
BioTechniques, Vol 32, Iss 6, Pp 1244-1246 (2002)
Externí odkaz:
https://doaj.org/article/2385cade10804535be6dd48429e14cf6
Autor:
Camille Ansermet, Robert Koesters, Dmitri Firsov, Vincent Bize, Sylvain Pradervand, Svetlana Nikolaeva, Olivier Bonny, Natsuko Tokonami, Marc Maillard, David Mordasini, Hugues Henry, Gabriel Centeno
Publikováno v:
Journal of the American Society of Nephrology : JASN, vol. 27, no. 10, pp. 2997-3004
Journal of the American Society of Nephrology : JASN
Journal of the American Society of Nephrology
Journal of the American Society of Nephrology : JASN
Journal of the American Society of Nephrology
The circadian clock controls a wide variety of metabolic and homeostatic processes in a number of tissues, including the kidney. However, the role of the renal circadian clocks remains largely unknown. To address this question, we performed a combine
Autor:
Emilie Boscardin, Johannes Loffing, Dominique Loffing-Cueni, Edith Hummler, Bernard C. Rossier, Chloé Sergi, Romain Perrier, Marc Maillard, Robert Koesters
Publikováno v:
Pflugers Archiv, vol. 469, no. 10, pp. 1387-1399
In adulthood, an induced nephron-specific deficiency of αENaC (Scnn1a) resulted in pseudohypoaldosteronism type 1 (PHA-1) with sodium loss, hyperkalemia, and metabolic acidosis that is rescued through high-sodium/low-potassium (HNa + /LK + ) diet. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a1ef2196951d1c6364d79f30b935ba
https://www.zora.uzh.ch/id/eprint/138075/
https://www.zora.uzh.ch/id/eprint/138075/