Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Robert Klausser"'
Publikováno v:
Liquids, Vol 4, Iss 1, Pp 1-31 (2023)
The pivotal role of proteins in pharmaceuticals is challenged by stability issues, making the study of inclusion bodies—a source of insoluble protein aggregates—increasingly relevant. This review outlines the critical procedures in inclusion body
Externí odkaz:
https://doaj.org/article/653fd609683140dab6b33c74c34b5f0a
Autor:
Robert Klausser, Julian Kopp, Eva Prada Brichtova, Florian Gisperg, Mohamed Elshazly, Oliver Spadiut
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/0c75c0b3269546b7b6fff4c1fd6cee78
Autor:
Robert Klausser, Julian Kopp, Eva Prada Brichtova, Florian Gisperg, Mohamed Elshazly, Oliver Spadiut
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Throughout the twenty-first century, the view on inclusion bodies (IBs) has shifted from undesired by-products towards a targeted production strategy for recombinant proteins. Inclusion bodies can easily be separated from the crude extract after cell
Externí odkaz:
https://doaj.org/article/b5951335e5a241109838bfc30067f375
Autor:
Julian Ebner, Diana Humer, Robert Klausser, Viktor Rubus, Reinhard Pell, Oliver Spadiut, Julian Kopp
Publikováno v:
Bioengineering, Vol 8, Iss 6, p 78 (2021)
Refolding is known as the bottleneck in inclusion body (IB) downstream processing in the pharmaceutical industry: high dilutions leading to large operating volumes, slow refolding kinetics and low refolding yields are only a few of the problems that
Externí odkaz:
https://doaj.org/article/13804829808243b9a7d88d961c13c66e
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629291
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef0a361d3161c1c5e21372772df3f417
https://doi.org/10.1007/978-1-0716-2930-7_9
https://doi.org/10.1007/978-1-0716-2930-7_9
Autor:
Britta Eggenreich, David Johannes Wurm, Vignesh Rajamanickam, Robert Klausser, Christoph Slouka, Oliver Spadiut
Publikováno v:
Journal of Biotechnology: X, Vol 7, Iss, Pp 100022-(2020)
Recombinant protein production in E. coli often leads to the formation of inclusion bodies (IBs). Although downstream processing of IBs has the reputation of being a great hurdle, advantages of IBs can be substantial. Highly pure recombinant protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1a517d0ae57bed5671564ff21a530374
https://pubmed.ncbi.nlm.nih.gov/34154734
https://pubmed.ncbi.nlm.nih.gov/34154734