Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Robert Kimmitt"'
Autor:
Edwin Carter, David J. Webb, Nicholas L. Mills, James W. Dear, Robert Kimmitt, Tariq E. Farrah, Peter J. Gallacher, Neeraj Dhaun, Atul Anand
Publikováno v:
Farrah, T E, Anand, A, Gallacher, P J, Kimmitt, R, Carter, E, Dear, J W, Mills, N L, Webb, D J & Dhaun, N 2019, ' Endothelin Receptor Antagonism Improves Lipid Profiles and Lowers PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) in Patients With Chronic Kidney Disease ', Hypertension, vol. 74, no. 2, pp. 323-330 . https://doi.org/10.1161/HYPERTENSIONAHA.119.12919
Hypertension (Dallas, Tex. : 1979)
Hypertension (Dallas, Tex. : 1979)
Supplemental Digital Content is available in the text.
Dyslipidemia is common in chronic kidney disease (CKD). Despite statins, many patients fail to adequately lower lipids and remain at increased risk of cardiovascular disease. Selective ETA (
Dyslipidemia is common in chronic kidney disease (CKD). Despite statins, many patients fail to adequately lower lipids and remain at increased risk of cardiovascular disease. Selective ETA (
Publikováno v:
F1000Research
Background: The past two decades have witnessed significant growth in non-commercial research and development (R&D) initiatives, particularly for neglected diseases, but there is limited understanding of the ways in which they compare with traditiona
Autor:
Vanessa Melville, Robert Kimmitt, David J. Webb, Iain M. MacIntyre, Ewan D. Kennedy, Wilna Oosthuyzen, Kayleigh E. Brown, Jane Goddard, Neeraj Dhaun, Rebecca Moorhouse
Publikováno v:
Hypertension. 64:296-304
Abstract— Hypertension and arterial stiffness are important independent cardiovascular risk factors in chronic kidney disease (CKD) to which endothelin-1 (ET-1) contributes. Loss of nocturnal blood pressure (BP) dipping is associated with CKD progr
Autor:
Joanna I. Clarke, David M. Wood, D. N. Bateman, Paul I. Dargan, D.J. Antoine, Jamie G. Cooper, J.H. Seymour, James W. Dear, Michael Eddleston, Alasdair Gray, A. D. B. Vliegenthart, David J. Webb, Robert Kimmitt, Natalie Z.M. Homer, Steff C. Lewis
Publikováno v:
Clinical Pharmacology and Therapeutics
Vliegenthart, B, Kimmitt, R A, Seymour, JH, Homer, N, Clarke, J I, Eddleston, M, Gray, A, Wood, D M, Dargan, P I, Cooper, J G, Antoine, D J, Webb, D, Lewis, S, Bateman, D N & Dear, J 2017, ' Circulating acetaminophen metabolites are toxicokinetic biomarkers of acute liver injury ', Clinical pharmacology and therapeutics, vol. 101, no. 4, pp. 531-540 . https://doi.org/10.1002/cpt.541
Vliegenthart, B, Kimmitt, R A, Seymour, JH, Homer, N, Clarke, J I, Eddleston, M, Gray, A, Wood, D M, Dargan, P I, Cooper, J G, Antoine, D J, Webb, D, Lewis, S, Bateman, D N & Dear, J 2017, ' Circulating acetaminophen metabolites are toxicokinetic biomarkers of acute liver injury ', Clinical pharmacology and therapeutics, vol. 101, no. 4, pp. 531-540 . https://doi.org/10.1002/cpt.541
Acetaminophen (paracetamol-APAP) is the most common cause of drug-induced liver injury in the Western world. Reactive metabolite production by cytochrome P450 enzymes (CYP-metabolites) causes hepatotoxicity. We explored the toxicokinetics of human ci
Autor:
Pajaree Lilitkarntakul, Neeraj Dhaun, Roger Corder, Jane Goddard, Jale Yuzugulen, David J. Webb, Robert Kimmitt, Elizabeth G. Wood
Publikováno v:
Life Sciences. 93(25-26)
Autor:
David J. Webb, Robert Kimmitt, Jane Goddard, Jale Yuzugulen, Neeraj Dhaun, Roger Corder, Elizabeth G. Wood
Publikováno v:
Life Sciences. 93(25-26)
Autor:
David J. Webb, Alicja Czopek, Titia Ruys, Robert Kimmitt, Dinesh Talwar, Neeraj Dhaun, James D. Cameron, Laura Willox, Craig Balmforth, Baljean Dhillon, May Hu Khei
Publikováno v:
Journal of Hypertension. 34:e303