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pro vyhledávání: '"Robert Keith Duncan"'
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109069- (2024)
Summary: Inner ear organoids recapitulate development and are intended to generate cell types of the otic lineage for applications such as basic science research and cell replacement strategies. Here, we use single-cell sequencing to study the cellul
Externí odkaz:
https://doaj.org/article/07610ad3827f49438b372d428cb8ae5b
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102295- (2021)
Inner ear organoids derived from pluripotent stem cells could be a useful model system to study development, disease, and regeneration. However, there is considerable heterogeneity in the size, morphology, and efficiency of organoid production using
Externí odkaz:
https://doaj.org/article/76c2d06772c14340ac12764f17d03061
Autor:
John J. Guinan, Shawn S. Goodman, Shannon M. Lefler, Robert Keith Duncan, Jeffery T. Lichtenhan
Publikováno v:
Frontiers in Surgery
Frontiers in Surgery, Vol 8 (2021)
Frontiers in Surgery, Vol 8 (2021)
Background: Loudness recruitment is commonly experienced by patients with putative endolymphatic hydrops. Loudness recruitment is abnormal loudness growth with high-level sounds being perceived as having normal loudness even though hearing thresholds
Autor:
Thomas Schrepfer, Stacy A Schaefer, Gabriel Corfas, Robert Keith Duncan, Guoqiang Wan, Atsuko Y. Higashi, Benjamin R. Loomis, Gregory R. Dressler
Producing hair cells of the inner ear is the major goal of ongoing research that combines advances in developmental and stem cell biology. The recent advent of an inner ear organoid protocol-resulting in three-dimensional stem cell-derived tissues re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f9ebd6ff40c1268eff32f484a42cbd
https://europepmc.org/articles/PMC5813733/
https://europepmc.org/articles/PMC5813733/
Autor:
John Matthew Velkey, Richard A. Altschuler, Gerhard W. Hill, Robert Keith Duncan, Liqian Liu, Erin K. Purcell
Publikováno v:
Stem Cells and Development. 21:2827-2837
Stem cell therapy holds great promise for treating neurodegenerative disease, but major barriers to effective therapeutic strategies remain. A complete understanding of the derived phenotype is required for predicting cell response once introduced in