Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Robert KY Cheng"'
Autor:
Yanjun Wang, James Brown, Richard Woessner, Alwin G Schuller, Alexandra Borodovsky, Dinesh Chandra, Deanna A Mele, Stephen Fawell, Joseph Shaw, Christine M Barbon, Minwei Ye, Laura Prickett, Nanhua Deng, Kris Sachsenmeier, James D Clarke, Bolan Linghu, Giles A Brown, Miles Congreve, Robert KY Cheng, Andrew S Dore, Edward Hurrell, Wenlin Shao, Corinne Reimer, Lisa Drew
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Methods We report here the development of a small molecule A2AR inhibitor including characterization of binding and inhibition of A2AR function with varying amounts of a stable version of adenosine. Functional activity was tested in both mouse and hu
Externí odkaz:
https://doaj.org/article/84f658f3a812430ca348354c04f4101a
Autor:
Robert KY Cheng
Publikováno v:
Crystals, Vol 10, Iss 3, p 215 (2020)
The advent of the X-ray free electron laser (XFEL) in the last decade created the discipline of serial crystallography but also the challenge of how crystal samples are delivered to X-ray. Early sample delivery methods demonstrated the proof-of-conce
Externí odkaz:
https://doaj.org/article/eac16416577b485e87c11e3917b2207f
Autor:
Alexandra, Borodovsky, Christine M, Barbon, Yanjun, Wang, Minwei, Ye, Laura, Prickett, Dinesh, Chandra, Joseph, Shaw, Nanhua, Deng, Kris, Sachsenmeier, James D, Clarke, Bolan, Linghu, Giles A, Brown, James, Brown, Miles, Congreve, Robert Ky, Cheng, Andrew S, Dore, Edward, Hurrell, Wenlin, Shao, Richard, Woessner, Corinne, Reimer, Lisa, Drew, Stephen, Fawell, Alwin G, Schuller, Deanna A, Mele
Publikováno v:
Journal for Immunotherapy of Cancer
Accumulation of extracellular adenosine within the microenvironment is a strategy exploited by tumors to escape detection by the immune system. Adenosine signaling through the adenosine 2A receptor (A2AR) on immune cells elicits a range of immunosupp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e18d0b7b2e055524a6b8afbab69cdcc
https://pubmed.ncbi.nlm.nih.gov/32727810
https://pubmed.ncbi.nlm.nih.gov/32727810