Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Robert K. Y. Zee-Cheng"'
Autor:
Robert E. Olson, Y.J.D. Chiu, Florence C. Lee, Anne L. Hall, Robert K.-Y. Zee-Cheng, Robert Kloepper
Publikováno v:
Archives of Biochemistry and Biophysics. 214:45-50
t-Butyl hydroperoxide has been studied as a possible competitive inhibitor of the vitamin K-dependent carboxylation of the pentapeptide PheLeuGluGluIle. Under standard carboxylating conditions the concentrations of reduced phylloquinone a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f806c9ed9dcf5301b426d401e97f5dfa
https://doi.org/10.1016/0003-9861(82)90006-6
https://doi.org/10.1016/0003-9861(82)90006-6
Autor:
C. C. Cheng, Robert K. Y. Zee-Cheng
Publikováno v:
Journal of Medicinal Chemistry. 21:291-294
A structure-activity relationship study was conducted on a number of bis(substituted aminoalkylamino)anthraquinones. These compounds were prepared by the condensation of substituted or unsubstituted leucoquinizarin with appropriate amines, followed b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53cecdb7223b08a6f62d219afd1d9035
https://doi.org/10.1021/jm00201a012
https://doi.org/10.1021/jm00201a012
Autor:
C. C. Cheng, Robert K. Y. Zee-Cheng
Publikováno v:
Journal of Medicinal Chemistry. 28:1216-1222
The similarity of the side-chain characteristics of 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]- anthraquinone (DHAQ), discovered by us in 1978, and those of the N-substituted imides of 3-nitro-1,8-naphthalic acid, discovered by othe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a04c61e1ca788ff0f5f790708881a47
https://doi.org/10.1021/jm00147a016
https://doi.org/10.1021/jm00147a016
Autor:
Robert K. Y. Zee-Cheng, C.C. Cheng
Publikováno v:
Journal of Medicinal Chemistry. 18:66-71
Salts of 2,3,8,9-tetrasubstituted alkoxy-, hydroxy-, and acetoxybenzo(c)phenanthridines as well as the corresponding 6-methoxy-5,6-dihydrobenzo(c)phenanthridines were prepared from appropriate chalcones through the tetralone and the 4b,10b,11,12-tetr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c9efa5ee89f93570608fdce23f6693f
https://doi.org/10.1021/jm00235a015
https://doi.org/10.1021/jm00235a015
Publikováno v:
Journal of Medicinal Chemistry. 29:1792-1795
Based on the observation of outstanding antineoplastic activity of a number of amino-substituted anthraquinones, thioxanthones, and N-(aminoethyl)-substituted naphthalimides, four types of amino-substituted p-benzoquinones were designed, synthesized,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc9c6f4da21dadecc7d129654ca07aad
https://doi.org/10.1021/jm00159a041
https://doi.org/10.1021/jm00159a041
Publikováno v:
Biochemical and Biophysical Research Communications. 94:1128-1132
A novel synthesis of optically active L-γ-carboxyglutamic acid (GLA), found in prothrombin and other vitamin K-dependent factors, is described. This method involves the formation of γ-carbanion of the protected glutamic acid esters by means of a no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c82760828f415acd67efe954fae3e4e5
https://doi.org/10.1016/0006-291x(80)90536-7
https://doi.org/10.1016/0006-291x(80)90536-7
Publikováno v:
Journal of Medicinal Chemistry. 30:1682-1686
A number of chloro-substituted [(aminoalkyl)amino]anthraquinones were synthesized and evaluated for their antineoplastic and cytotoxic activity. Treatment of 5,8-dichloroquinizarin with substituted amines in pyridine resulted in the replacement of on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8c8101609d701bca260f4be5ee0ac6
https://doi.org/10.1021/jm00392a028
https://doi.org/10.1021/jm00392a028
Autor:
C. C. Cheng, Robert K. Y. Zee-Cheng
Publikováno v:
Journal of Medicinal Chemistry. 22:28-32
A number of ureidothiazole and ureidothiadiazole derivatives related to ethyl 4-[[(2-thiazolylamino)carbonyl]-amino]benzoate were prepared and evaluated against the leukemia P-388 tumor system in mice. Preliminary structure-activity relationship stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e0ac3350f00566bebe7ba79bd77167
https://doi.org/10.1021/jm00187a007
https://doi.org/10.1021/jm00187a007
Autor:
Robert K. Y. Zee-Cheng, C. C. Cheng
Publikováno v:
Journal of Medicinal Chemistry. 19:882-886
Some positional and structural isomers of coralyne were prepared and evaluated in the P388 lymphocytic leukemia system for their inhibitory activity. The levels of antileukemic activity of coralyne, neocoralyne, isocoralyne, and stracoralyne were com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e48e7d62dffdd2dde8a322017ab0d0
https://doi.org/10.1021/jm00229a005
https://doi.org/10.1021/jm00229a005
Publikováno v:
Journal of Medicinal Chemistry. 19:337-339
Some 2,3-bis(substituted methyl)naphthazarins and related compounds were synthesized by the Diels-Alder reaction of benzoquinone and 2,3-dimethylbutadiene followed by oxidation and substitution reactions. These compounds were prepared as potential bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe345d1ba5667646126d5434d4d2331
https://doi.org/10.1021/jm00224a029
https://doi.org/10.1021/jm00224a029