Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Robert K. Lesniak"'
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/31373fb702a44d3084ffa95d848e189a
Autor:
Guo-Bo Li, Shengyong Yang, Michael A. McDonough, Jürgen Brem, James Spencer, Martine I. Abboud, Juan-Carlos Jiménez-Castellanos, Christopher T. Lohans, Christopher J. Schofield, Ian J. Clifton, Matthew B. Avison, Robert K. Lesniak
Publikováno v:
Chemical communications (Cambridge, England). 53(43)
Crystallographic analyses of the VIM-5 metallo-β-lactamase (MBL) with isoquinoline inhibitors reveal non zinc ion binding modes. Comparison with other MBL-inhibitor structures directed addition of a zinc-binding thiol enabling identification of pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0dc52f06977decd3ee4c2cb78e9e02e
https://pubmed.ncbi.nlm.nih.gov/28470248
https://pubmed.ncbi.nlm.nih.gov/28470248
Autor:
Jürgen Brem, Hwanho Choi, Anna M. Rydzik, Michael A. McDonough, Robert K. Lesniak, Timothy D. W. Claridge, Jasmin Mecinović, Christopher J. Schofield, Amjad Khan, Jos J. A. G. Kamps
Publikováno v:
Chemistry - A European Journal. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cd0ea389b4b5806dd6931d89081ebfa
https://doi.org/10.1002/chem.201680462
https://doi.org/10.1002/chem.201680462
Autor:
Jos J A G, Kamps, Amjad, Khan, Hwanho, Choi, Robert K, Lesniak, Jürgen, Brem, Anna M, Rydzik, Michael A, McDonough, Christopher J, Schofield, Timothy D W, Claridge, Jasmin, Mecinović
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
γ‐Butyrobetaine hydroxylase (BBOX) is a non‐heme FeII‐ and 2‐oxoglutarate‐dependent oxygenase that catalyzes the stereoselective hydroxylation of an unactivated C−H bond of γ‐butyrobetaine (γBB) in the final step of carnitine biosynt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c3612a5cb2d8fd782f653bdcff9f0dcd
https://pubmed.ncbi.nlm.nih.gov/26660433
https://pubmed.ncbi.nlm.nih.gov/26660433
Autor:
Adam M. Wawro, Chandresh R. Gajera, Steven A. Baker, Robert K. Leśniak, Curt R. Fischer, Nay L. Saw, Mehrdad Shamloo, Thomas J. Montine
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Imbalance of excitatory and inhibitory neurotransmission is implicated in a wide range of psychiatric and neurologic disorders. Here we tested the hypothesis that insertion of a methyl group on the stereogenic alpha carbon of l-Glu or l-Gln
Externí odkaz:
https://doaj.org/article/0b1cf771b7094dddbe45b3302eac42de