Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Robert K. Clark"'
Publikováno v:
Human gene therapy methods. 27(3)
Adeno-associated virus (AAV) vectors are increasingly popular in gene therapy because they are unassociated with human disease, replication dependent, and less immunogenic than other viral vectors and can infect a variety of cell types. These vectors
Publikováno v:
Experimental dermatology. 23(9)
Equine laminitis is a common, painful, debilitating condition of the hoof that is a leading cause of disability in horses, often necessitating euthanasia. The equine hoof represents an extreme evolutionary adaptation of an epidermal structure homolog
Autor:
Robert K. Clark, Raymond F. White, William J. Price, Frank C. Barone, D. E. Griswold, Giora Z. Feuerstein, D. B. Schmidt, H. M. Sarau, L. M. Hillegass, M. N. Tzimas, J. J. Foley
Publikováno v:
Molecular and Chemical Neuropathology. 24:13-30
In previous studies, we have used histological methods to characterize cellular changes, and validated the use of the myeloperoxidase (MPO) activity assay to quantitate increased neutrophil infiltration in ischemic stroke. We also identified increase
Publikováno v:
Spermatogenesis. 1(2)
Testis expressed gene 11 (Tex11) is essential for meiosis and male fertility in the mouse. Currently, little is known about the control of spermatogenesis in non-rodent animal models such as pigs. Here, we characterized the sequence and expression pr
Publikováno v:
Cardiovascular Research. 28:1808-1814
Objective: The aim was to investigate whether interleukin-lβ (IL-1β) plays a role in modulating the adhesion of monocytes and neutrophils to vascular smooth muscle cells, and to identify what molecules on these cells may be involved in the adhesion
Autor:
Eliot H. Ohlstein, Raymond F. White, Frank C. Barone, Giora Z. Feuerstein, Robert K. Clark, William J. Price, Barbara Storer
Publikováno v:
Brain Research. 623:77-82
Neuron-specific enolase (NSE) is an isoform of the glycolytic enzyme, enolase, and is found in neurons and neuroendocrine cells. We evaluated cerebral immunohistologic and plasma changes in NSE in rats from 2 h to 15 days following permanent or trans
Autor:
Steve Trulli, Christine Debouck, Deborah Matour, Robert M. Craig, Robert K. Clark, Zdenka L. Jonak, Elizabeth V. Lee, Russell Greig, Edward Mark Henri
Publikováno v:
AIDS Research and Human Retroviruses. 9:23-32
Our goal has been to develop a safe and effective system that would allow us to explore the functions of the human immunodeficiency virus (HIV) envelope. We have generated a human lymphoid cell line (TF228.1.16) that stably expresses functional HIV e
Autor:
William J. Price, Frank C. Barone, Giora Z. Feuerstein, R. F. White, Henry M. Sarau, L. M. Hillegass, Robert K. Clark, E.V. Lee, Don E. Griswold
Publikováno v:
Journal of Neuroscience Research. 29:336-345
Two different techniques were utilized to identify the infiltration of polymorphonuclear leukocytes (PMN) into cerebral tissue following focal ischemia: histologic analysis and a modified myeloperoxidase (MPO) activity assay. Twenty-four hours after
Publikováno v:
Clinical immunology and immunopathology. 88(1)
Regeneration is generally considered to be a phenomenon restricted to amphibians in which amputated limbs reform and regrow. We have recently noted a strain of mouse, the MRL, which displays a remarkable capacity for cartilagenous wound closure and p
Optical examination of load transfer in riveted lap joints using portable holographic interferometry
Publikováno v:
SPIE Proceedings.
In mechanically fastened single lap joints, such as those employed on aircraft fuselage skin splices, there are two distinct mechanisms of load transfer. At low values of load the transfer occurs primarily through friction between the component sheet