Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Robert K Shepherd"'
Autor:
Felix Peter Aplin, Kirstan Anne Vessey, Chi D Luu, Robyn H Guymer, Robert K Shepherd, Erica Lucy Fletcher
Publikováno v:
Frontiers in Neuroanatomy, Vol 10 (2016)
In rodents and felines, intravitreal administration of adenosine triphosphate (ATP) has been shown to induce photoreceptor death providing a tractable model of retinal degeneration in these species. This study investigated the long term effects of ph
Externí odkaz:
https://doaj.org/article/9334a71c7fe24d74a8a13c630b6abb20
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164867 (2016)
Cochlear implants electrically stimulate spiral ganglion neurons (SGNs) in order to provide speech cues to severe-profoundly deaf patients. In normal hearing cochleae the SGNs depend on endogenous neurotrophins secreted by sensory cells in the organ
Externí odkaz:
https://doaj.org/article/df04790a54704996b5df19eaa701c61c
Autor:
Matthew A. Petoe, BEng (Hons), PhD, Carla J. Abbott, BOptom, PhD, Samuel A. Titchener, BEng (Hons), PhD, Maria Kolic, BOrth, William G. Kentler, BEng, David A.X. Nayagam, BEng (Hons), PhD, Elizabeth K. Baglin, BOrth, Jessica Kvansakul, MSc, PhD, Nick Barnes, PhD, Janine G. Walker, PhD, Lewis Karapanos, BBMed (Hons), MD, Myra B. McGuinness, MBiostat, PhD, Lauren N. Ayton, BOptom, PhD, Chi D. Luu, BOrth (Hons), PhD, Penelope J. Allen, MBBS, FRANZCO, Peter J. Blamey, Robert J. Briggs, Owen Burns, Stephanie B. Epp, Dean Johnson, Hugh J. McDermott, Ceara McGowan, Rodney E. Millard, Peter M. Seligman, Robert K. Shepherd, Mohit N. Shivdasani, Nicholas C. Sinclair, Patrick C. Thien, Joel Villalobos, Chris E. Williams, Jonathan Yeoh, Kiera A. Young
Publikováno v:
Ophthalmology Science, Vol 5, Iss 1, Pp 100525- (2025)
Purpose: To assess the feasibility of a second-generation (44-channel) suprachoroidal retinal prosthesis for provision of functional vision in recipients with end-stage retinitis pigmentosa (RP) over 2.7 years. Design: Prospective, single-arm, unmask
Externí odkaz:
https://doaj.org/article/3a20a1a10d28475b9c47d7d3672f0e3e
Autor:
Lauren N Ayton, Peter J Blamey, Robyn H Guymer, Chi D Luu, David A X Nayagam, Nicholas C Sinclair, Mohit N Shivdasani, Jonathan Yeoh, Mark F McCombe, Robert J Briggs, Nicholas L Opie, Joel Villalobos, Peter N Dimitrov, Mary Varsamidis, Matthew A Petoe, Chris D McCarthy, Janine G Walker, Nick Barnes, Anthony N Burkitt, Chris E Williams, Robert K Shepherd, Penelope J Allen, Bionic Vision Australia Research Consortium
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115239 (2014)
Retinal visual prostheses ("bionic eyes") have the potential to restore vision to blind or profoundly vision-impaired patients. The medical bionic technology used to design, manufacture and implant such prostheses is still in its relative infancy, wi
Externí odkaz:
https://doaj.org/article/b9cb3c37192546c5b6a4c81a3d6f7157
Autor:
David A X Nayagam, Richard A Williams, Penelope J Allen, Mohit N Shivdasani, Chi D Luu, Cesar M Salinas-LaRosa, Sue Finch, Lauren N Ayton, Alexia L Saunders, Michelle McPhedran, Ceara McGowan, Joel Villalobos, James B Fallon, Andrew K Wise, Jonathan Yeoh, Jin Xu, Helen Feng, Rodney Millard, Melanie McWade, Patrick C Thien, Chris E Williams, Robert K Shepherd
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97182 (2014)
To assess the safety and efficacy of chronic electrical stimulation of the retina with a suprachoroidal visual prosthesis.Seven normally-sighted feline subjects were implanted for 96-143 days with a suprachoroidal electrode array and six were chronic
Externí odkaz:
https://doaj.org/article/9eed3a29f32240d3a09b8968ea2f0b71
Autor:
Jeremy L. Pinyon, Georg vonJonquieres, Edward N. Crawford, Amr Al Abed, John M. Power, Matthias Klugmann, Cherylea J. Browne, David M. Housley, Andrew K. Wise, James B. Fallon, Robert K. Shepherd, John Y. Lin, Catherine McMahon, David McAlpine, Catherine S. Birman, Waikong Lai, Ya Lang Enke, Paul M. Carter, James F. Patrick, Robert D. Gay, Corinne Marie, Daniel Scherman, Nigel H. Lovell, Gary D. Housley
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract Viral vectors and lipofection‐based gene therapies have dispersion‐dependent transduction/transfection profiles that thwart precise targeting. The study describes the development of focused close‐field gene electrotransfer (GET) techno
Externí odkaz:
https://doaj.org/article/1f120ece41dd42df991a8e5de27489c2
Autor:
Patrick J Atkinson, Andrew K Wise, Brianna O Flynn, Bryony A Nayagam, Clifford R Hume, Stephen J O'Leary, Robert K Shepherd, Rachael T Richardson
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52338 (2012)
The cochlear implant provides auditory cues to profoundly deaf patients by electrically stimulating the residual spiral ganglion neurons. These neurons, however, undergo progressive degeneration after hearing loss, marked initially by peripheral fibr
Externí odkaz:
https://doaj.org/article/c6f87e92dea946a59d7d19dbbf4db9b2
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18733 (2011)
Exogenous neurotrophin delivery to the deaf cochlea can prevent deafness-induced auditory neuron degeneration, however, we have previously reported that these survival effects are rapidly lost if the treatment stops. In addition, there are concerns t
Externí odkaz:
https://doaj.org/article/825a3e123aa340818143f413e82c0b24
Autor:
Robert K. Shepherd
Publikováno v:
Healthcare Technology Letters (2020)
Externí odkaz:
https://doaj.org/article/c0a7760307154ed8a23118601f03a9f9
Autor:
Anne M. Kong, Gregory J. Dusting, Shiang Y. Lim, Priyadharshini Sivakumaran, Owen Burns, Damián Hernández, Robert K. Shepherd, Rodney E. Millard
Publikováno v:
Bioelectricity
Background: Cardiomyocytes derived from pluripotent stem cells are immature. Maturation of cardiomyocytes is a multifactorial dynamic process that involves various factors in vivo that cannot be fully recapitulated in vitro. Here, we report a novel t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64cbd5a68ddf8970fa2c709d21e395f1
https://doi.org/10.1089/bioe.2020.0035
https://doi.org/10.1089/bioe.2020.0035