Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Robert K, Delong"'
Publikováno v:
Bioengineering, Vol 10, Iss 5, p 512 (2023)
Conserved omicron RNA (COR) is a 40 base long 99.9% conserved sequence in SARS-CoV-2 Omicron variant, predicted to form a stable stem loop, the targeted cleavage of which can be an ideal next step in controlling the spread of variants. The Cas9 enzym
Externí odkaz:
https://doaj.org/article/1e232f8390ee4fa08c4e11dc0aede5d9
Autor:
Abeera Bhatti, Robert K. DeLong
Publikováno v:
ACS Pharmacology & Translational Science. 6:220-228
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f51309425b7f179c3bb2d981373b7605
https://doi.org/10.1021/acsptsci.2c00195
https://doi.org/10.1021/acsptsci.2c00195
Autor:
Elza Neelima Mathew, Miranda N Hurst, Baolin Wang, Vaibhav Murthy, Yuntao Zhang, Robert K DeLong
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243802 (2020)
Zinc oxide (ZnO) NP is considered as a nanoscale chemotherapeutic. Thus, the drug delivery of this inorganic NP is of considerable importance. Ras mutations are common in cancer and the activation of this signaling pathway is a hallmark in carcinoma,
Externí odkaz:
https://doaj.org/article/23f1b79ca75846a6b66de4cb52395977
Autor:
Hanah F. Huber, Majid Jaberi-Douraki, Sarah DeVader, Cesar Aparicio-Lopez, Juliet Nava-Chavez, Xuan Xu, Nuwan Indika Millagaha Gedara, Natasha N. Gaudreault, Robert K. Delong
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 1012 (2021)
The emergence of SARS-CoV-2 variants is cause for concern, because these may become resistant to current vaccines and antiviral drugs in development. Current drugs target viral proteins, resulting in a critical need for RNA-targeted nanomedicines. To
Externí odkaz:
https://doaj.org/article/83313e956ff0473c9b069ebae336eb1e
Autor:
Robert K. DeLong, Hanah Huber, Cesar Aparicio-Lopez, Abeera Bhatti, Ryan Swanson, Tej B. Shrestha, Natasha N. Gaudreault
Publikováno v:
ACS Pharmacology & Translational Science. 5:449-457
Recent interest in nanomedicine has skyrocketed because of mRNA vaccine lipid nanoparticles (LNPs) against COVID-19. Ironically, despite this success, the innovative nexus between nanotechnology and biochemistry, and the impact of nanoparticles on en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d754deac136e8ddb7dc1e9983da530e
https://doi.org/10.1021/acsptsci.2c00041
https://doi.org/10.1021/acsptsci.2c00041
Autor:
Janet M. Sasso, Barbara J. B. Ambrose, Rumiana Tenchov, Ruchira S. Datta, Matthew T. Basel, Robert K. DeLong, Qiongqiong Angela Zhou
Publikováno v:
Journal of Medicinal Chemistry. 65:6975-7015
In the past decade, there has been a shift in research, clinical development, and commercial activity to exploit the many physiological roles of RNA for use in medicine. With the rapid success in the development of lipid-RNA nanoparticles for mRNA va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9e6503a62eaa5b982f506b7a552858
https://doi.org/10.1021/acs.jmedchem.2c00024
https://doi.org/10.1021/acs.jmedchem.2c00024
Autor:
Sarah Young, Sagar Rayamajhi, Rowena A. Woode, Santosh Aryal, Sarah Schneider, Garry Glaspell, Steve Ensley, Tracy Miesner, Kartik Ghosh, Robert K. Delong, Pratiksha Khanal, Heman Shakeri, Zhoumeng Lin, Megan C. Niederwerder, Lane L. Clarke, Mary Lynn Higginbotham, Majid Jaberi-Douraki, Tej B. Shrestha, Elza Neelima Mathew, Ryan Swanson, Reza Mazloom, Ramesh Marasini
Publikováno v:
Nanomedicine. 16:1857-1872
The aim of this study was to investigate the distribution, tolerance, and anticancer and antiviral activity of Zn-based physiometacomposites (PMCs). Manganese, iron, nickel and cobalt-doped ZnO, ZnS or ZnSe were synthesized. Cell uptake, distribution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3312e0dea5ac8ce8cac6547af420c9e
https://doi.org/10.2217/nnm-2021-0179
https://doi.org/10.2217/nnm-2021-0179
Autor:
Majid Jaberi-Douraki, Santosh Aryal, Kartik Ghosh, C. Russell Middaugh, John M. Dean, Nancy A. Monteiro-Riviere, Garry Glaspell, Seok Chan Park, Meghana Ramani, Robert K. Delong, Tuyen Duong Thanh Nguyen, Seong-O Choi, Parwathy Chandran, Daniel J. Davis
Publikováno v:
ACS applied bio materials. 3(1)
Aberrant splicing and protein interaction of Ras binding domain (RBD) are associated with melanoma drug resistance. Here, cobalt or nickel doped zinc oxide (ZnO) physiometacomposite (PMC) materials bind to RNA and peptide shown by Ninhydrin staining,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf4ed725ed204435457e7acaffa667fb
https://pubmed.ncbi.nlm.nih.gov/35019433
https://pubmed.ncbi.nlm.nih.gov/35019433
Publikováno v:
Nanotechnology, Science and Applications, Vol 2010, Iss default, Pp 53-63 (2010)
Robert K DeLong1, Christopher M Reynolds1, Yaneika Malcolm1, Ashley Schaeffer1, Tiffany Severs2, Adam Wanekaya21Department of Biomedical Science (Cell and Molecular Biology Program), 2Department of Chemistry, Missouri State University, Springfield, M
Externí odkaz:
https://doaj.org/article/3b0bcf9de0ff4e4e8350c35b7b12e9a5
Publikováno v:
Nanoscale Research Letters
Nanoscale Research Letters, Vol 16, Iss 1, Pp 1-9 (2021)
Nanoscale Research Letters, Vol 16, Iss 1, Pp 1-9 (2021)
FePO4 NPs are of special interest in food fortification and biomedical imaging because of their biocompatibility, high bioavailability, magnetic property, and superior sensory performance that do not cause adverse organoleptic effects. These characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957fb9ca34ad3312ea4a451a45000566
http://europepmc.org/articles/PMC8626714
http://europepmc.org/articles/PMC8626714