Zobrazeno 1 - 10
of 79 342
pro vyhledávání: '"Robert K"'
Autor:
Jule Pinter, David J. Tunnicliffe, Pooshwikaa Karunikaikumar, Anastasios Anastasiadis, Robert K. Hills
Publikováno v:
Systematic Reviews, Vol 13, Iss 1, Pp 1-6 (2024)
Abstract Background Patients with kidney failure often lack robust evidence because they are excluded from randomized trials. Trial emulation provides an alternative approach to derive treatment effect estimates when randomized trials cannot be condu
Externí odkaz:
https://doaj.org/article/994d9b8e30eb4cd1934d9e67e2cb9478
Autor:
Naheema S. Gordon, Elspeth K. McGuigan, Michaela Ondasova, Jennifer Knight, Laura A. Baxter, Sascha Ott, Robert K. Hastings, Maurice P. Zeegers, Nicholas D. James, K. K. Cheng, Anshita Goel, Minghao Yu, Roland Arnold, Richard T. Bryan, Douglas G. Ward
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-4 (2024)
Abstract Background and aims Several non-invasive tests for detecting bladder cancer (BC) are commercially available and are based on detecting small panels of BC-associated mutations and/or methylation changes in urine DNA. However, it is not clear
Externí odkaz:
https://doaj.org/article/948476a9f2e2449e9f9c0f8d0705374d
Autor:
Austin M. Gabel, Andrea E. Belleville, James D. Thomas, Jose Mario Bello Pineda, Robert K. Bradley
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Alternative polyadenylation (APA) affects most human genes and is recurrently dysregulated in all studied cancers. However, the mechanistic origins of this dysregulation are incompletely understood. Results We describe an unbiased
Externí odkaz:
https://doaj.org/article/3e221b88df34409f92e5f01950f1eca2
Autor:
Michael J. Caplan, Richard Baldwin, Xiangyun Yin, Alexander Grishin, Stephanie Eisenbarth, Hugh A. Sampson, Kim Bottomly, Robert K. Prud’homme
Publikováno v:
Communications Materials, Vol 5, Iss 1, Pp 1-11 (2024)
Abstract Immune modulation and desensitization is a growing field of research and clinical investigation that requires precise delivery of antigens to immune system cells. Nanoparticles (NPs) have emerged as excellent candidates for antigen delivery,
Externí odkaz:
https://doaj.org/article/70ea25fc008b413291803f7ea6e74b35
Autor:
Thomas J. K. Buchner, Toshihiko Fukushima, Amirhossein Kazemipour, Stephan-Daniel Gravert, Manon Prairie, Pascal Romanescu, Philip Arm, Yu Zhang, Xingrui Wang, Steven L. Zhang, Johannes Walter, Christoph Keplinger, Robert K. Katzschmann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Robotic locomotion in unstructured terrain demands an agile, adaptive, and energy-efficient architecture. To traverse such terrains, legged robots use rigid electromagnetic motors and sensorized drivetrains to adapt to the environment active
Externí odkaz:
https://doaj.org/article/e6b63db7e7614a2aa7d50ed8b2090165
Autor:
Adriane Halik, Marlon Tilgner, Patricia Silva, Natalia Estrada, Robert Altwasser, Ekaterina Jahn, Michael Heuser, Hsin-An Hou, Marta Pratcorona, Robert K. Hills, Klaus H. Metzeler, Laurene Fenwarth, Anna Dolnik, Christine Terre, Klara Kopp, Olga Blau, Martin Szyska, Friederike Christen, Jan Krönke, Loïc Vasseur, Bob Löwenberg, Jordi Esteve, Peter J. M. Valk, Matthieu Duchmann, Wen-Chien Chou, David C. Linch, Hartmut Döhner, Rosemary E. Gale, Konstanze Döhner, Lars Bullinger, Kenichi Yoshida, Frederik Damm
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-18 (2024)
Abstract Background Deletions and partial losses of chromosome 7 (chr7) are frequent in acute myeloid leukemia (AML) and are linked to dismal outcome. However, the genomic landscape and prognostic impact of concomitant genetic aberrations remain inco
Externí odkaz:
https://doaj.org/article/c4bde76aa3284c6f887bca011315517d
Autor:
Ruchika Dehinwal, Tata Gopinath, Richard D. Smith, Robert K. Ernst, Dieter M. Schifferli, Matthew K. Waldor, Francesca M. Marassi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Outer membrane vesicles (OMVs) produced by Gram-negative bacteria have key roles in cell envelope homeostasis, secretion, interbacterial communication, and pathogenesis. The facultative intracellular pathogen Salmonella Typhimurium increases
Externí odkaz:
https://doaj.org/article/0b2fa93830f14e3a9591beec10a5f1a1
Autor:
Ivan V. Kuzmin, Ruben Soto Acosta, Layne Pruitt, Perry T. Wasdin, Kritika Kedarinath, Keziah R. Hernandez, Kristyn A. Gonzales, Kharighan Hill, Nicole G. Weidner, Chad Mire, Taylor B. Engdahl, Woohyun J. Moon, Vsevolod Popov, James E. Crowe, Ivelin S. Georgiev, Mariano A. Garcia-Blanco, Robert K. Abbott, Alexander Bukreyev
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The rodent-borne Andes virus (ANDV) causes a severe disease in humans. We developed an ANDV mRNA vaccine based on the M segment of the viral genome, either with regular uridine (U-mRNA) or N1-methylpseudouridine (m1Ψ-mRNA). Female mice immu
Externí odkaz:
https://doaj.org/article/b9d9f5258a8943afbcc90d9e051b9c63
Autor:
Jia Zhao, Shenghui Liang, Haoning Howard Cen, Yanjun Li, Robert K. Baker, Balwinder Ruprai, Guang Gao, Chloe Zhang, Huixia Ren, Chao Tang, Liangyi Chen, Yanmei Liu, Francis C. Lynn, James D. Johnson, Timothy J. Kieffer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Remarkable advances in protocol development have been achieved to manufacture insulin-secreting islets from human pluripotent stem cells (hPSCs). Distinct from current approaches, we devised a tunable strategy to generate islet spheroids enr
Externí odkaz:
https://doaj.org/article/1bdf64aed5f74d41bf7cbec2f67ff56c
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract In this work we demonstrate a miniaturised imaging system based around a time-gated SPAD array operating in a “chip-on-tip” manner. Two versions of the system are demonstrated, each measuring 23 mm × 23 mm × 28 mm with differing fields
Externí odkaz:
https://doaj.org/article/2dc142188f654738a505ece9d6a5bab8