Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Robert Jan, Doll"'
Autor:
Ahnjili Zhuparris, Ghobad Maleki, Liesbeth van Londen, Ingrid Koopmans, Vincent Aalten, Iris E. Yocarini, Vasileios Exadaktylos, Albert van Hemert, Adam Cohen, Pim Gal, Robert-Jan Doll, Geert Jan Groeneveld, Gabriël Jacobs, Wessel Kraaij
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Drug development for mood disorders can greatly benefit from the development of robust, reliable, and objective biomarkers. The incorporation of smartphones and wearable devices in clinical trials provide a unique opportunity to monitor beha
Externí odkaz:
https://doaj.org/article/7fc77d26e65c4a94b6761c3ca90e1519
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-11 (2021)
Abstract Background In the current study, we aimed to develop an algorithm based on biomarkers obtained through non- or minimally invasive procedures to identify healthy elderly subjects who have an increased risk of abnormal cerebrospinal fluid (CSF
Externí odkaz:
https://doaj.org/article/a7689931f0644552b7feafa5d357d2b7
Autor:
Ahnjili ZhuParris, Annika A. de Goede, Iris E. Yocarini, Wessel Kraaij, Geert Jan Groeneveld, Robert Jan Doll
Publikováno v:
Sensors, Vol 23, Iss 11, p 5243 (2023)
Background: Central nervous system (CNS) disorders benefit from ongoing monitoring to assess disease progression and treatment efficacy. Mobile health (mHealth) technologies offer a means for the remote and continuous symptom monitoring of patients.
Externí odkaz:
https://doaj.org/article/bacd9d144234429399130a6e0e0b0c26
Autor:
Charlotte Bakker, Tim Tasker, Jan Liptrot, Ellen P. Hart, Erica S. Klaassen, Robert Jan Doll, Giles A. Brown, Alastair Brown, Miles Congreve, Malcolm Weir, Fiona H. Marshall, David M. Cross, Geert Jan Groeneveld, Pradeep J. Nathan
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-19 (2021)
Abstract Background The cholinergic system and M1 receptor remain an important target for symptomatic treatment of cognitive dysfunction. The selective M1 receptor partial agonist HTL0018318 is under development for the symptomatic treatment of Demen
Externí odkaz:
https://doaj.org/article/8f25b2ca13ee46c9988b118de2ad5f58
Autor:
Ahnjili ZhuParris, Matthijs D. Kruizinga, Max van Gent, Eva Dessing, Vasileios Exadaktylos, Robert Jan Doll, Frederik E. Stuurman, Gertjan A. Driessen, Adam F. Cohen
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Introduction: The duration and frequency of crying of an infant can be indicative of its health. Manual tracking and labeling of crying is laborious, subjective, and sometimes inaccurate. The aim of this study was to develop and technically validate
Externí odkaz:
https://doaj.org/article/92ada131bdd64d0396f1b07f430f173a
Publikováno v:
Neuromodulation, 25(7), 1006-1014. Elsevier
Objectives: There is a lack of clinically relevant measures for quantification of maladaptive mechanisms of the nociceptive system leading to chronic pain. Recently, we developed a method that tracks nociceptive detection thresholds (NDTs) using intr
Autor:
Matthijs D. Kruizinga, Ahnjili Zhuparris, Eva Dessing, Fas J. Krol, Arwen J. Sprij, Robert‐Jan Doll, Frederik E. Stuurman, Vasileios Exadaktylos, Gertjan J. A. Driessen, Adam F. Cohen
Publikováno v:
Pediatric Pulmonology, 57(3), 761-767. Pediatric Pulmonology
Pediatric Pulmonology, 57(3), 761-767. Wiley
Pediatric Pulmonology, 57(3), 761-767. Wiley
IntroductionCoughing is a common symptom in pediatric lung disease and cough frequency has been shown to be correlated to disease activity in several conditions. Automated cough detection could provide a noninvasive digital biomarker for pediatric cl
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-11 (2021)
Alzheimer's Research and Therapy
ISSUE=13;TITLE=Alzheimer's Research and Therapy
Alzheimer's Research & Therapy
Alzheimer's Research and Therapy
ISSUE=13;TITLE=Alzheimer's Research and Therapy
Alzheimer's Research & Therapy
Background In the current study, we aimed to develop an algorithm based on biomarkers obtained through non- or minimally invasive procedures to identify healthy elderly subjects who have an increased risk of abnormal cerebrospinal fluid (CSF) amyloid
Autor:
Eva Thijssen, Soma Makai‐Bölöni, Emilie van Brummelen, Jonas den Heijer, Yalcin Yavuz, Robert‐Jan Doll, Geert Jan Groeneveld
Publikováno v:
Movement Disorders Clinical Practice, 9(8), 1074-1084. WILEY
Background: Movement Disorder Society-Unified Parkinson's Rating Scale Part III (MDS-UPDRS III) is the gold standard for assessing medication effects in patients with Parkinson's disease (PD). However, short and rater-independent measurements would b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ba824fb6b6d3a4cb21fbbbf9c4a58b
https://hdl.handle.net/1887/3479834
https://hdl.handle.net/1887/3479834
Autor:
Hemme Hijma, Ingrid Koopmans, Erica Klaassen, Robert Jan Doll, Rob Zuiker, Geert Jan Groeneveld
Publikováno v:
British Journal of Clinical Pharmacology. WILEY
British Journal of Clinical Pharmacology
British Journal of Clinical Pharmacology
Aim: We assessed whether total sleep deprivation (TSD) in combination with pain tests yields a reliable method to assess altered pain thresholds, which subsequently may be used to investigate (novel) analgesics in healthy subjects. Methods: This was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c870fe4bea324c7d5f9946f41924fab7
https://hdl.handle.net/1887/3572118
https://hdl.handle.net/1887/3572118