Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Robert J. Wiener"'
Autor:
Danielle N. D’Erminio, Kaya A. Adelzadeh, Ashley M. Rosenberg, Robert J. Wiener, Olivia M. Torre, Emily D. Ferreri, Philip Nasser, Kevin D. Costa, Woojin M. Han, Alice H. Huang, James C. Iatridis
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110883- (2024)
Summary: Intervertebral disc (IVD) defects heal poorly and can cause back pain and disability. We identified that IVD herniation injury heals regeneratively in neonatal mice until postnatal day 14 (p14) and shifts to fibrotic healing by p28. This age
Externí odkaz:
https://doaj.org/article/ee8939875d934d66b1c0389ff1beea90
Autor:
Chrystian Junqueira Alves, Rafael Dariolli, Jonathan Haydak, Sangjo Kang, Theodore Hannah, Robert J. Wiener, Stefanie DeFronzo, Rut Tejero, Gabriele L. Gusella, Aarthi Ramakrishnan, Rodrigo Alves Dias, Alexandre Wojcinski, Santosh Kesari, Li Shen, Eric A. Sobie, José Paulo Rodrigues Furtado de Mendonça, Evren U. Azeloglu, Hongyan Zou, Roland H. Friedel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-23 (2021)
Biomechanical mechanisms orchestrating stem cell dynamics in development remain unclear. Here the authors show that guidance receptor Plexin-B2 organizes actomyosin contractility, cytoskeletal tension and adhesion during multicellular development of
Externí odkaz:
https://doaj.org/article/ec4433536a404ae78838f90b72c22b29
Autor:
Rhodora C. Calizo, Smiti Bhattacharya, J. G. Coen van Hasselt, Chengguo Wei, Jenny S. Wong, Robert J. Wiener, Xuhua Ge, Nicholas J. Wong, Jia-Jye Lee, Christina M. Cuttitta, Gomathi Jayaraman, Vivienne H. Au, William Janssen, Tong Liu, Hong Li, Fadi Salem, Edgar A. Jaimes, Barbara Murphy, Kirk N. Campbell, Evren U. Azeloglu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Kinase inhibitors used in chemotherapy are known for their adverse effects on kidney physiology. Here, Calizo et al. show that dasatinib is associated with a higher risk of glomerular toxicity compared to other kinase inhibitors, due to deleterious e
Externí odkaz:
https://doaj.org/article/8269d038cbb047b6863d44efd06fc28f
Autor:
Fu Jia, Robert J. Wiener, Liping Yu, Börje Haraldsson, Zhengzi Yi, John Cijiang He, Kerstin Ebefors, Margaret H. Baron, Ilse Daehn, Weijia Zhang, Evren U. Azeloglu
Publikováno v:
Kidney Int
Emerging evidence of crosstalk between glomerular cells in pathological settings provides opportunities for novel therapeutic discovery. Here we investigated underlying mechanisms of early events leading to filtration barrier defects of podocyte and
Autor:
William J. Janssen, Hong Li, Tong Liu, J. G. Coen van Hasselt, Xuhua Ge, Gomathi Jayaraman, Jia-Jye Lee, Christina M. Cuttitta, Evren U. Azeloglu, Nicholas J. Wong, Robert J. Wiener, Fadi Salem, Edgar A. Jaimes, Rhodora Cristina Calizo, Smiti Bhattacharya, Chengguo Wei, Vivienne H. Au, Kirk N. Campbell, Jenny Wong, Barbara Murphy
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications, 10, 2061
Nature Communications
Nature Communications, 10, 2061
Nephrotoxicity is a critical adverse event that leads to discontinuation of kinase inhibitor (KI) treatment. Here we show, through meta-analyses of FDA Adverse Event Reporting System, that dasatinib is associated with high risk for glomerular toxicit
Autor:
Santosh Kesari, Theodore C Hannah, R. A. Dias, Alexandre Wojcinski, Eric A. Sobie, Gabriele Luca Gusella, Hongyan Zou, Chrystian Junqueira Alves, Evren U. Azeloglu, Robert J. Wiener, Li Shen, Jonathan C Haydak, Aarthi Ramakrishnan, Roland H. Friedel, Rafael Dariolli, José Paulo Rodrigues Furtado de Mendonça, Sangjo Kang, Rut Tejero, Stefanie DeFronzo
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-23 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-23 (2021)
During morphogenesis, molecular mechanisms that orchestrate biomechanical dynamics across cells remain unclear. Here, we show a role of guidance receptor Plexin-B2 in organizing actomyosin network and adhesion complexes during multicellular developme
Publikováno v:
Biophysical Journal. 120:63a
Autor:
Jia-Jye Lee, Kevin D. Costa, Charles Wang, Robert J. Wiener, Hongyu Qiu, Shaunrick Stoll, Ben Ma, Ning Zhou
Publikováno v:
Cardiovascular Research. 113:171-182
Increased aortic stiffness is a fundamental manifestation of hypertension. However, the molecular mechanisms involved remain largely unknown. We tested the hypothesis that abnormal intrinsic vascular smooth muscle cell (VSMC) mechanical properties in
The United States has a robust nonprofit housing sector. These organizations have made significant contributions toward alleviating the country's housing problems. This chapter presents several important and innovative adaptations that are being made
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24d887ec9679491272947fe8c5d23dcc
https://doi.org/10.1201/9781315112350-7
https://doi.org/10.1201/9781315112350-7
Autor:
Robert J. Wiener, Stephen E. Barton
Publikováno v:
Journal of Housing and the Built Environment. 29:403-422
Inclusionary zoning, commonly known as inclusionary housing (IH), first originated in the United States in the early‐1970s in the wealthy suburbs of Washington, DC. Since then, the epicenter of IH practice in the U.S. has moved west to California.