Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: protocol of a multicentre, open-label, parallel-group, phase II-III, randomised, superiority study (CAIRO6)

Autor: Koen P. Rovers, Checca Bakkers, Geert A. A. M. Simkens, Jacobus W. A. Burger, Simon W. Nienhuijs, Geert-Jan M. Creemers, Anna M. J. Thijs, Alexandra R. M. Brandt-Kerkhof, Eva V. E. Madsen, Ninos Ayez, Nadine L. de Boer, Esther van Meerten, Jurriaan B. Tuynman, Miranda Kusters, Nina R. Sluiter, Henk M. W. Verheul, Hans J. van der Vliet, Marinus J. Wiezer, Djamila Boerma, Emma C. E. Wassenaar, Maartje Los, Cornelis B. Hunting, Arend G. J. Aalbers, Niels F. M. Kok, Koert F. D. Kuhlmann, Henk Boot, Myriam Chalabi, Schelto Kruijff, Lukas B. Been, Robert J. van Ginkel, Derk Jan A. de Groot, Rudolf S. N. Fehrmann, Johannes H. W. de Wilt, Andreas J. A. Bremers, Philip R. de Reuver, Sandra A. Radema, Karin H. Herbschleb, Wilhelmina M. U. van Grevenstein, Arjen J. Witkamp, Miriam Koopman, Nadia Haj Mohammad, Eino B. van Duyn, Walter J. B. Mastboom, Leonie J. M. Mekenkamp, Joost Nederend, Max J. Lahaye, Petur Snaebjornsson, Cornelis Verhoef, Hanneke W. M. van Laarhoven, Aeilko H. Zwinderman, Jeanette M. Bouma, Onno Kranenburg, Iris van ‘t Erve, Remond J. A. Fijneman, Marcel G. W. Dijkgraaf, Patrick H. J. Hemmer, Cornelis J. A. Punt, Pieter J. Tanis, Ignace H. J. T. de Hingh, Dutch Peritoneal Oncology Group (DPOG), Dutch Colorectal Cancer Group (DCCG)

Publikováno v: BMC Cancer, Vol 19, Iss 1, Pp 1-15 (2019)

Abstract Background Upfront cytoreductive surgery with HIPEC (CRS-HIPEC) is the standard treatment for isolated resectable colorectal peritoneal metastases (PM) in the Netherlands. This study investigates whether addition of perioperative systemic th

Externí odkaz: https://doaj.org/article/0eae7e00e09f44039f07a47639a0e680

CD20-selective inhibition of CD47-SIRPα 'don't eat me' signaling with a bispecific antibody-derivative enhances the anticancer activity of daratumumab, alemtuzumab and obinutuzumab

Autor: Peter E. van Bommel, Yuan He, Ilona Schepel, Mark A. J. M. Hendriks, Valerie R. Wiersma, Robert J. van Ginkel, Tom van Meerten, Emanuele Ammatuna, Gerwin Huls, Douwe F. Samplonius, Wijnand Helfrich, Edwin Bremer

Publikováno v: OncoImmunology, Vol 7, Iss 2 (2018)

Here, we report on a novel bispecific antibody-derivative, designated RTX-CD47, with unique capacity for CD20-directed inhibition of CD47-SIRPα “don't eat me” signaling. RTX-CD47 comprises a CD20-targeting scFv antibody fragment derived from rit

Externí odkaz: https://doaj.org/article/28534e798d5449938af49fe87651c684

(Cost-)effectiveness of an individualised risk prediction tool (PERSARC) on patient’s knowledge and decisional conflict among soft-tissue sarcomas patients: protocol for a parallel cluster randomised trial (the VALUE-PERSARC study)

Autor: Cornelis Verhoef, Rick L Haas, Elske M van den Akker-van Marle, Leti van Bodegom-Vos, Michiel A J van de Sande, Ellen G Engelhardt, Perla Marang-van de Mheen, Anouk A Kruiswijk, Yvonne M Schrage, Robert J van Ginkel, Han Bonenkamp, Marc HA Bemelmans, Ibtissam Acem, Stefanie Hakkesteegt, Roos F Bleckman, Marloes van Duijvenbode, Nicolette Leijerzapf, Jos A van der Hage, Robert J.P. van der Wal

Publikováno v: BMJ Open, Vol 13, Iss 11 (2023)

Introduction Current treatment decision-making in high-grade soft-tissue sarcoma (STS) care is not informed by individualised risks for different treatment options and patients’ preferences. Risk prediction tools may provide patients and profession

Externí odkaz: https://doaj.org/article/1bc6e7a42b9748709211f848ccf38441

Multimodality treatment of undifferentiated pleomorphic soft tissue sarcoma of the extremity (eUPS) in the elderly

Autor: Roos F. Bleckman, Ibtissam Acem, Veroniek M. van Praag, Desirée M.J. Dorleijn, Cornelis Verhoef, Yvonne M. Schrage, Rick M.L. Haas, Michiel A.J. van de Sande, null the collaborative Persarc research group, Han Bonenkamp, Robert J. van Ginkel, Dirk J. Grünhagen, Lee M. Jeys, Johnny Keller, Emelie Styring, Joanna Szkandera, Olga Zaikova

Publikováno v: European Journal of Surgical Oncology, 48(5), 985-993. W.B. Saunders
European Journal of Surgical Oncology, 48, 985-993
European Journal of Surgical Oncology, 48, 5, pp. 985-993
European Journal of Surgical Oncology, 48(5), 985-993. ELSEVIER SCI LTD
Bleckman, R F, Acem, I, van Praag, V M, Dorleijn, D M J, Verhoef, C, Schrage, Y M, Haas, R M L, van de Sande, M A J & the collaborative PERSARC research group 2022, ' Multimodality treatment of undifferentiated pleomorphic soft tissue sarcoma of the extremity (eUPS) in the elderly ', European Journal of Surgical Oncology, vol. 48, no. 5, pp. 985-993 . https://doi.org/10.1016/j.ejso.2021.12.008
European Journal of Surgical Oncology, 48, 985-993. ELSEVIER SCI LTD

Introduction: This subgroup analysis of undifferentiated pleomorphic soft tissue sarcoma of the extremity (eUPS) from the PERSARC collaborative group aimed to achieve a more personalized multimodality treatment approach for primary eUPS in elderly pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51abbbdaf7cd60b7a381ed0cf900a768
http://www.scopus.com/inward/record.url?scp=85121383518&partnerID=8YFLogxK

Corrigendum to ‘Age-related differences of oncological outcomes in primary extremity soft tissue sarcoma: a multistate model including 6260 patients’ [Eur J Cancer 141 (2020) 128-136]

Autor: Ibtissam Acem, Cornelis Verhoef, Anja J. Rueten-Budde, Dirk J. Grünhagen, Winan J. van Houdt, Michiel A.J. van de Sande, Will Aston, Han Bonenkamp, Ingrid M.E. Desar, Peter C. Ferguson, Marta Fiocco, Hans Gelderblom, Robert J. van Ginkel, Winette van der Graaf, Anthony M. Griffin, Rick L. Haas, Jos A. van der Hage, Andrew J. Hayes, Lee M. Jeys, Johnny Keller, Minna K. Laitinen, Andreas Leithner, Katja Maretty-Kongstad, Toshifumi Ozaki, Rob Pollock, Veroniek M. van Praag, Myles J. Smith, Maria A. Smolle, Emelie Styring, Joanna Szkandera, Kazuhiro Tanaka, Per-Ulf Tunn, Madeleine Willegger, Reinard Windhager, Jay S. Wunder, Olga Zaikova

Publikováno v: European Journal of Cancer. 162:247-249

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d176df357adbb4f6aa40604c861f3b0f
https://doi.org/10.1016/j.ejca.2021.12.002