Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Robert J. Tomko, Jr."'
Autor:
Emily Gutierrez-Morton, Cory Haluska, Liam Collins, Raed Rizkallah, Robert J. Tomko, Jr., Yanchang Wang
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114492- (2024)
Summary: In budding yeast, the nucleolus serves as the site to sequester Cdc14, a phosphatase essential for mitotic exit. Nucleolar proteins Tof2, Net1, and Fob1 are required for this sequestration. Although it is known that these nucleolar proteins
Externí odkaz:
https://doaj.org/article/c14a0422d5d34e1abe32b69ce456fc10
Autor:
Ryan Higgins, Marie-Helene Kabbaj, Delaney Sherwin, Lauren A. Howell, Alexa Hatcher, Robert J. Tomko, Jr., Yanchang Wang
Publikováno v:
Cell Reports, Vol 32, Iss 2, Pp 107898- (2020)
Summary: The accumulation of misfolded proteins is associated with multiple neurodegenerative disorders, but it remains poorly defined how this accumulation causes cytotoxicity. Here, we demonstrate that the Cdc48/p97 segregase machinery drives the c
Externí odkaz:
https://doaj.org/article/64665d8392944950b3c1f13929211b39
Publikováno v:
Cell Reports, Vol 26, Iss 2, Pp 483-495.e5 (2019)
Summary: The 26S proteasome is the central ATP-dependent protease in eukaryotes and is essential for organismal health. Proteasome assembly is mediated by several dedicated, evolutionarily conserved chaperone proteins. These chaperones associate tran
Externí odkaz:
https://doaj.org/article/9e515e8be83e43a681241c3474409c3a