Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Robert J. Talmadge"'
Publikováno v:
PLoS ONE, Vol 17, Iss 11 (2022)
Muscle injury can be caused by strenuous exercise, repetitive tasks or external forces. Populations that have experienced selection for high locomotor activity may have evolutionary adaptations that resist exercise-induced injury and/or enhance the a
Externí odkaz:
https://doaj.org/article/9a7563f8f679434d8bf0055959c65cae
Publikováno v:
Biochemistry and Biophysics Reports, Vol 28, Iss , Pp 101182- (2021)
Huntington's disease (HD) causes neurological impairments, as well as muscle dysfunction, including smaller neuromuscular junctions (NMJs). This study assessed the expression levels of the subunits of the nicotinic acetylcholine receptor (nAChR) in m
Externí odkaz:
https://doaj.org/article/496216020d6f4e1f96f433d850e60e4e
Autor:
Jon-Philippe K. Hyatt, Lisa eNguyen, Allison E. Hall, Ashley M. Huber, Jessica C. Kocan, Julie A. Mattison, Rafael ede Cabo, Jeannine R. Larocque, Robert J. Talmadge
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
Shifts in myosin heavy chain (MHC) expression within skeletal muscle can be induced by a host of stimuli including, but not limited to, physical activity, alterations in neural activity, aging, and diet or obesity. Here, we hypothesized that both age
Externí odkaz:
https://doaj.org/article/b9d33b8a4180426aa1f0a57e40ab272b
Autor:
Sabrina Metzger, D Scott Jobe, Shannon H. Romer, Matthew C Wright, Andrew A. Voss, Kristiana Peraza, Mark M. Rich, Brent D. Foy, Robert J. Talmadge, Long-Sheng Song
Publikováno v:
The Journal of General Physiology
This study reveals defects in the transverse tubules of skeletal muscle in the R6/2 model of Huntington’s disease. These results serve as a foundation to simulate electrical activity in skeletal muscle and may help explain the motor deficits in Hun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad59573ebacb4e8fb8f6d97a4f5e3258
https://doi.org/10.1085/jgp.202012637
https://doi.org/10.1085/jgp.202012637
Publikováno v:
The Journal of General Physiology
Mice lacking BK potassium channels have weakness with stimulation of peripheral nerve, but not muscle, which is caused by a defect in neuromuscular transmission. Prolonging the motor neuron action potential fully normalizes in vivo strength.
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Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8636de4409605fbce16b48870ffc23
https://doi.org/10.1085/jgp.201912526
https://doi.org/10.1085/jgp.201912526
Publikováno v:
Comparative Exercise Physiology. 12:183-192
Blood lactate concentration ([LA]) response to exercise challenges can be used to assess fitness in horses. Most equine conditioning programs (CP) that have been studied are based on regular bouts of exercise of similar to increasing levels of intens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29e77d5203ecb16f6553328a3efb05fa
https://doi.org/10.3920/cep160019
https://doi.org/10.3920/cep160019
Publikováno v:
Proceedings of the Royal Society B: Biological Sciences
The southern alligator lizard (Elgaria multicarinata) exhibits a courtship behaviour during which the male firmly grips the female's head in his jaws for many hours at a time. This extreme behaviour counters the conventional wisdom that reptilian mus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a55170104847e5c4bb3d5e51320dcb11
https://doi.org/10.1098/rspb.2020.1578
https://doi.org/10.1098/rspb.2020.1578
Autor:
Edward Jo, Jared W. Coburn, Lee E. Brown, Andrew J. Galpin, James R. Bagley, Irene S. Tobias, Nancy L. Segal, Robert J. Talmadge, Jose A. Arevalo, Katherine E. Bathgate
Publikováno v:
European journal of applied physiology. 118(10)
Physical health and function depend upon both genetic inheritance and environmental factors (e.g., exercise training). To enhance the understanding of heritability/adaptability, we explored the skeletal muscle health and physiological performance of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d48d81d88f8d0a838a3733f30cc461
https://pubmed.ncbi.nlm.nih.gov/30006671
https://pubmed.ncbi.nlm.nih.gov/30006671
Autor:
Andrew A. Voss, William L. Romine, Mark M. Rich, Qingbo Wang, Shannon H. Romer, Robert J. Talmadge, Eric J. Reed, Ahmad Khedraki
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 37(34)
Huntington's disease (HD) is a progressive and fatal degenerative disorder that results in debilitating cognitive and motor dysfunction. Most HD studies have focused on degeneration of the CNS. We previously discovered that skeletal muscle from trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8b0988606ccd7a439feb7e897a1826
https://pubmed.ncbi.nlm.nih.gov/28724748
https://pubmed.ncbi.nlm.nih.gov/28724748
Publikováno v:
Proceedings of the National Academy of Sciences. 110:9160-9165
Huntington disease is a progressive and fatal genetic disorder with debilitating motor and cognitive defects. Chorea, rigidity, dystonia, and muscle weakness are characteristic motor defects of the disease that are commonly attributed to central neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1af31680ac481b50d8150b4f0431a94
https://doi.org/10.1073/pnas.1220068110
https://doi.org/10.1073/pnas.1220068110