Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Robert J. Stiles"'
Autor:
Marshall D. Behrens, Robert J. Stiles, Gennett M. Pike, Laura A. Sikkink, Yongxian Zhuang, Jia Yu, Liewei Wang, Judy C. Boughey, Matthew P. Goetz, Mark J. Federspiel
Publikováno v:
Molecular Therapy: Oncolytics, Vol 27, Iss , Pp 239-255 (2022)
Historically, the clinical utility of oncolytic virotherapy as a treatment for a wide range of cancer types was first demonstrated by three pilot human clinical trials conducted in Japan in the 1970s and 1980s using a wild-type Urabe mumps virus (MuV
Externí odkaz:
https://doaj.org/article/b9ed91b0cb974385bc37be3b4a346fb0
Autor:
Kimberly G. Laffey, Robert J. Stiles, Melissa J. Ludescher, Tessa R. Davis, Shariq S. Khwaja, Richard J. Bram, Peter J. Wettstein, Venkataraman Ramachandran, Christopher A. Parks, Edwin E. Reyes, Alejandro Ferrer, Jenna M. Canfield, Cory E. Johnson, Richard D. Hammer, Diana Gil, Adam G. Schrum
Publikováno v:
Proceedings of the National Academy of Sciences. 119
During normal T cell development in mouse and human, a low-frequency population of immature CD4−CD8−double-negative (DN) thymocytes expresses early, mature αβ T cell antigen receptor (TCR). We report that these early αβ TCR+ DN (EADN) cells a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49fb8d831d6e2e0cf783d478a153ef87
https://doi.org/10.1073/pnas.2118529119
https://doi.org/10.1073/pnas.2118529119
Autor:
Tessa R. Davis, Aaron J. Johnson, Jamie Rossjohn, Mark A. Daniels, Alejandro Ferrer, Adam G. Schrum, Deanne Hebrink, Kevin D. Pavelko, Stephen E. P. Smith, Jenna M. Canfield, Katelynn M. Wilton, Peter J. Wettstein, Dietmar J. Kappes, Diana Gil, Larry R. Pease, Scott R. Burrows, James McCluskey, April M. Huseby Kelcher, Claudia Neuhauser, Zhenjun Chen, Steven C. Neier, Eva M. Carmona, Andrew H. Limper, Robert J. Stiles
Publikováno v:
Sci Immunol
During αβ T cell development, T cell antigen receptor (TCR) engagement transduces biochemical signals through a protein-protein interaction (PPI) network that dictates dichotomous cell fate decisions. It remains unclear how signal specificity is co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fad1a3e06f1347ccfdcf6b2fb62e3d
https://doi.org/10.1126/sciimmunol.aal2201
https://doi.org/10.1126/sciimmunol.aal2201
Autor:
Jenna M Canfield, Alejandro Ferrer, Steven C Neier, Katelynn M Wilton, Robert J Stiles, Tessa Davis, Adam G Schrum, Diana Gil Pages
Publikováno v:
The Journal of Immunology. 204:61.15-61.15
Upon positive selection of conventional αβ T cells, CD4+ CD8+ double-positive (DP) cells transition to single-positive (SP) and reduce their responsiveness to weak peptide/MHC ligands (affinity threshold conversion, ATC). We report that ATC actuall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b95605fccbad6c768fd129089240a81
https://doi.org/10.4049/jimmunol.204.supp.61.15
https://doi.org/10.4049/jimmunol.204.supp.61.15
Autor:
Chi-Ren Shyu, Tessa R. Davis, Venkataraman Ramachandran, Adam G. Schrum, Richard J. Bram, Kimberly G. Laffey, Diana Gil, Cory E. Johnson, Peter J. Wettstein, Richard D. Hammer, Melissa Ludescher, Shariq S. Khwaja, Robert J. Stiles
Publikováno v:
Blood. 134:1463-1463
T cell lymphoblastic leukemia (T-ALL) is an aggressive cancer arising from transformed thymocytes. Most human T-ALL involves hyperactive NOTCH signaling that is often caused by activating NOTCH mutations. However, the identification of specific molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ceae8e6e213f4b3a6f8463d713892e2
https://doi.org/10.1182/blood-2019-131897
https://doi.org/10.1182/blood-2019-131897
Autor:
Alfredo Oliveros, Brendan K. Reed, Christopher A. Parks, Robert J. Stiles, Katelynn M. Wilton, Maja Radulovic, Adam G. Schrum, Steven C. Neier, Alejandro Ferrer, Macarena Gil-Pagés
Publikováno v:
Behavioral and Brain Functions : BBF
Background There is significant interest in the generation of improved assays to clearly identify experimental mice possessing functional vision, a property that could qualify mice for inclusion in behavioral and neuroscience studies. Widely employed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ffe333d601e8c5a4d91aa87fa720dc1
https://doi.org/10.1186/1744-9081-9-35
https://doi.org/10.1186/1744-9081-9-35
Publikováno v:
Lab animal. 42(2)
Timed matings of mice are often carried out to obtain offspring of a precise age when required for a study. Timed matings involve housing male and female mice together for a limited time period, typically overnight. A limitation of this practice is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a426cdd2431829a7e7f7d17aab061f3
https://pubmed.ncbi.nlm.nih.gov/23340789
https://pubmed.ncbi.nlm.nih.gov/23340789