Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Robert J. Sims"'
Autor:
Li Zhu, Mark A. Brown, Robert J. Sims, Gayatri R. Tiwari, Hui Nie, R. Dayne Mayfield, Haley O. Tucker
Publikováno v:
Cells, Vol 12, Iss 13, p 1695 (2023)
The SMYD family is a unique class of lysine methyltransferases (KMTases) whose catalytic SET domain is split by a MYND domain. Among these, Smyd1 was identified as a heart- and skeletal muscle-specific KMTase and is essential for cardiogenesis and sk
Externí odkaz:
https://doaj.org/article/ffb17e4a2a0941e0ac7a6678931a78e4
Autor:
Brett A. Johnson, Margaret Coutts, Hillary M. Vo, Xinya Hao, Nida Fatima, Maria J. Rivera, Robert J. Sims, Michael J. Neel, Young-Jin Kang, Edwin S. Monuki
Publikováno v:
Fluids and Barriers of the CNS, Vol 15, Iss 1, Pp 1-18 (2018)
Abstract Background Choroid plexus epithelial cells express high levels of transthyretin, produce cerebrospinal fluid and many of its proteins, and make up the blood-cerebrospinal fluid barrier. Choroid plexus epithelial cells are vital to brain heal
Externí odkaz:
https://doaj.org/article/551c14112ec94f029772f4f8b11b9ce2
Publikováno v:
BioTechniques, Vol 34, Iss 5, Pp 938-940 (2003)
Externí odkaz:
https://doaj.org/article/45f264929f3a45028e490326cd65c0b6
Autor:
Tucker, Li Zhu, Mark A. Brown, Robert J. Sims, Gayatri R. Tiwari, Hui Nie, R. Dayne Mayfield, Haley O.
Publikováno v:
Cells; Volume 12; Issue 13; Pages: 1695
The SMYD family is a unique class of lysine methyltransferases (KMTases) whose catalytic SET domain is split by a MYND domain. Among these, Smyd1 was identified as a heart- and skeletal muscle-specific KMTase and is essential for cardiogenesis and sk
Autor:
Robert J. Sims, Jennifer A. Mertz, Cyril H. Benes, Arnaud Amzallag, Patricia Greninger, Barbara M. Bryant, Charlie Hatton, Archana Bommi-Reddy, Nicole E. Follmer, Kerry L. Spillane, Richard C. Centore, Andrew R. Conery
This file contains the following: source data for the graphs shown in Figure 3A (GI50, Z sub G1, and Z G1 increase); source data for the heatmap and graph shown in Figure 3B (expression fold change, log2 fold change, and gene score); qPCR source data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40fa3455abc8c42632cc94f85959ac3d
https://doi.org/10.1158/0008-5472.22409192
https://doi.org/10.1158/0008-5472.22409192
Autor:
Robert J. Sims, Jennifer A. Mertz, Cyril H. Benes, Arnaud Amzallag, Patricia Greninger, Barbara M. Bryant, Charlie Hatton, Archana Bommi-Reddy, Nicole E. Follmer, Kerry L. Spillane, Richard C. Centore, Andrew R. Conery
This file contains 4 supplementary tables: Table S1 provides the expression values of the indicated genes (RMA) in BETi sensitive and insensitive cell lines; Table S2 shows the enrichment of subtypes of cell lines following selection with the indicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d00d1e4e57a5da6c3a1586537c1f6b2
https://doi.org/10.1158/0008-5472.22409195
https://doi.org/10.1158/0008-5472.22409195
Autor:
Robert J. Sims, Jennifer A. Mertz, Cyril H. Benes, Arnaud Amzallag, Patricia Greninger, Barbara M. Bryant, Charlie Hatton, Archana Bommi-Reddy, Nicole E. Follmer, Kerry L. Spillane, Richard C. Centore, Andrew R. Conery
This file contains the legends for the six supplementary figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b8f2e2a9b9f1fb87de3e92f609882b
https://doi.org/10.1158/0008-5472.22409201
https://doi.org/10.1158/0008-5472.22409201
Autor:
Robert J. Sims, Jennifer A. Mertz, Cyril H. Benes, Arnaud Amzallag, Patricia Greninger, Barbara M. Bryant, Charlie Hatton, Archana Bommi-Reddy, Nicole E. Follmer, Kerry L. Spillane, Richard C. Centore, Andrew R. Conery
This file contains six supplementary figures: Figure S1 (related to Figure 1) provides additional characterization of the BETi tolerant cell lines; Figure S2 (related to Figure 1) provides additional information regarding gene expression changes in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b310678d015766b4818364e2e8ed04f2
https://doi.org/10.1158/0008-5472.22409198.v1
https://doi.org/10.1158/0008-5472.22409198.v1
Autor:
Robert J. Sims, Jennifer A. Mertz, Cyril H. Benes, Arnaud Amzallag, Patricia Greninger, Barbara M. Bryant, Charlie Hatton, Archana Bommi-Reddy, Nicole E. Follmer, Kerry L. Spillane, Richard C. Centore, Andrew R. Conery
Small-molecule inhibitors of the bromodomain and extraterminal (BET) family of proteins are being tested in clinical trials for a variety of cancers, but patient selection strategies remain limited. This challenge is partly attributed to the heteroge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9d6cdbfe556f14c97575ca1740b94a
https://doi.org/10.1158/0008-5472.c.6507722
https://doi.org/10.1158/0008-5472.c.6507722
Autor:
Robert J. Sims, Jennifer A. Mertz, Cyril H. Benes, Arnaud Amzallag, Patricia Greninger, Barbara M. Bryant, Charlie Hatton, Archana Bommi-Reddy, Nicole E. Follmer, Kerry L. Spillane, Richard C. Centore, Andrew R. Conery
This file contains the source of all cell lines used for the work described in the manuscript as well as the methods by which cell lines are authenticated at the repositories.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c89307cf9062e93ea40dc522f080c0
https://doi.org/10.1158/0008-5472.22409207
https://doi.org/10.1158/0008-5472.22409207