Zobrazeno 1 - 10
of 387
pro vyhledávání: '"Robert J. Schmitz"'
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Single-cell ATAC-seq has emerged as a powerful approach for revealing candidate cis-regulatory elements genome-wide at cell-type resolution. However, current single-cell methods suffer from limited throughput and high costs. Here, we present
Externí odkaz:
https://doaj.org/article/65a61f05fd444a49b30f7e8bf231a9cd
Autor:
Yinwen Zhang, Hosung Jang, Ziliang Luo, Yinxin Dong, Yangyang Xu, Yamini Kantamneni, Robert J Schmitz
Publikováno v:
PLoS Genetics, Vol 20, Iss 7, p e1011358 (2024)
Heterochromatin is critical for maintaining genome stability, especially in flowering plants, where it relies on a feedback loop involving the H3K9 methyltransferase, KRYPTONITE (KYP), and the DNA methyltransferase CHROMOMETHYLASE3 (CMT3). The H3K9 d
Externí odkaz:
https://doaj.org/article/26144c321cf64908a1a35b0b380cdb12
Corrigendum: Mining the Utricularia gibba genome for insulator-like elements for genetic engineering
Autor:
Daniel Laspisa, Eudald Illa-Berenguer, Sohyun Bang, Robert J. Schmitz, Wayne Parrott, Jason Wallace
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/be419fc381d0437781a614e5dab760c0
Autor:
Christopher B. Cunningham, Emily A. Shelby, Elizabeth C. McKinney, Robert J. Schmitz, Allen J. Moore, Patricia J. Moore
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-12 (2023)
Abstract Background The function of DNA methyltransferase genes of insects is a puzzle, because an association between gene expression and methylation is not universal for insects. If the genes normally involved in cytosine methylation are not influe
Externí odkaz:
https://doaj.org/article/5722c9a9aaa74fb4a0234f484c1287a9
Autor:
Iryna Ivasyk, Leonora Olivos-Cisneros, Stephany Valdés-Rodríguez, Marie Droual, Hosung Jang, Robert J. Schmitz, Daniel J. C. Kronauer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Although DNA methylation is an important gene regulatory mechanism in mammals, its function in arthropods remains poorly understood. Studies in eusocial insects have argued for its role in caste development by regulating gene expression and
Externí odkaz:
https://doaj.org/article/21082b8878894067a823c7c7b569ce7f
Autor:
Daniel Laspisa, Eudald Illa-Berenguer, Sohyun Bang, Robert J. Schmitz, Wayne Parrott, Jason Wallace
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
IntroductionGene expression is often controlled via cis-regulatory elements (CREs) that modulate the production of transcripts. For multi-gene genetic engineering and synthetic biology, precise control of transcription is crucial, both to insulate th
Externí odkaz:
https://doaj.org/article/12324a2eff204611889186ee75a95fe4
Autor:
C. Robin Buell, Christopher Dardick, Wayne Parrott, Robert J. Schmitz, Patrick M. Shih, Chung-Jui Tsai, Breeanna Urbanowicz
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Humans have been modifying plant traits for thousands of years, first through selection (i.e., domestication) then modern breeding, and in the last 30 years, through biotechnology. These modifications have resulted in increased yield, more efficient
Externí odkaz:
https://doaj.org/article/66464bb0f53e4c9ab30d6ed2e98e92c0
Autor:
Yinwen Zhang, Hosung Jang, Rui Xiao, Ioanna Kakoulidou, Robert S. Piecyk, Frank Johannes, Robert J. Schmitz
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The molecular origins of epialleles remain unknown. Here, the authors show that a positive feedback loop between H3K9me2 and CMT2/3 is a major contributing factor to the origins of spontaneous epialleles and that heterochromatin is a quantitative tra
Externí odkaz:
https://doaj.org/article/92bbdcf244a549d7bd6b64dcded0745b
Autor:
Aileen R. Ferraro, Abigail J. Ameri, Zefu Lu, Masayuki Kamei, Robert J. Schmitz, Zachary A. Lewis
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-14 (2021)
Abstract Background Regulation of chromatin accessibility and transcription are tightly coordinated processes. Studies in yeast and higher eukaryotes have described accessible chromatin regions, but little work has been done in filamentous fungi. Res
Externí odkaz:
https://doaj.org/article/8384983b1a9b44daa2cddbc8e034cf42
Autor:
Yadollah Shahryary, Aikaterini Symeonidi, Rashmi R. Hazarika, Johanna Denkena, Talha Mubeen, Brigitte Hofmeister, Thomas van Gurp, Maria Colomé-Tatché, Koen J.F. Verhoeven, Gerald Tuskan, Robert J. Schmitz, Frank Johannes
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-22 (2020)
Abstract Stochastic changes in DNA methylation (i.e., spontaneous epimutations) contribute to methylome diversity in plants. Here, we describe AlphaBeta, a computational method for estimating the precise rate of such stochastic events using pedigree-
Externí odkaz:
https://doaj.org/article/61ed9b5876c743479bc2eb35c96c2191