Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Robert J. Schmittling"'
Autor:
John H. Sampson, Duane A. Mitchell, Gordana Vlahovic, Darell Bigner, Henry S. Friedman, Allan H. Friedman, Roger E. McLendon, Patrick Healy, James E. Herndon, Weihua Xie, Pam Norberg, Robert J. Schmittling, Smita K. Nair, Luis Sanchez-Perez, Gary E. Archer, Elizabeth A. Reap, Kristen A. Batich
supplementary figures and legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b5fcb114cba3c65477708b3f9a182cf
https://doi.org/10.1158/1078-0432.22467126
https://doi.org/10.1158/1078-0432.22467126
Autor:
John H. Sampson, Duane A. Mitchell, Peter E. Fecci, Darell D. Bigner, Henry S. Friedman, Allan H. Friedman, Roger E. McLendon, Gordana Vlahovic, Annick Desjardins, Kent J. Weinhold, Taylor M. Broome, Anastasie M. Dunn-Pirio, Smita K. Nair, Anirudh Saraswathula, Mohammed K. Hossain-Ibrahim, John S. Yi, Katherine A. Riccione, Adam M. Swartz, Olivia C. Campbell, Patrick C. Gedeon, Kendra L. Congdon, Patrick Healy, James E. Herndon, Pamela K. Norberg, Robert J. Schmittling, Gary E. Archer, Luis Sanchez-Perez, Kristen A. Batich, Carter M. Suryadevara, Elizabeth A. Reap
Summary of adverse events with possible relation to study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6d423c21966ce90fefe65599e1ca46
https://doi.org/10.1158/0008-5472.22417785.v1
https://doi.org/10.1158/0008-5472.22417785.v1
Autor:
John H. Sampson, Duane A. Mitchell, Peter E. Fecci, Darell D. Bigner, Henry S. Friedman, Allan H. Friedman, Roger E. McLendon, Gordana Vlahovic, Annick Desjardins, Kent J. Weinhold, Taylor M. Broome, Anastasie M. Dunn-Pirio, Smita K. Nair, Anirudh Saraswathula, Mohammed K. Hossain-Ibrahim, John S. Yi, Katherine A. Riccione, Adam M. Swartz, Olivia C. Campbell, Patrick C. Gedeon, Kendra L. Congdon, Patrick Healy, James E. Herndon, Pamela K. Norberg, Robert J. Schmittling, Gary E. Archer, Luis Sanchez-Perez, Kristen A. Batich, Carter M. Suryadevara, Elizabeth A. Reap
Ex vivo analysis of CMV pp65-specific CD8+ T cells in circulation before and after immunotherapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ddd773de4481cf84d8cddf24412e18
https://doi.org/10.1158/0008-5472.22417791.v1
https://doi.org/10.1158/0008-5472.22417791.v1
Autor:
John H. Sampson, Darell D. Bigner, Luis Sanchez-Perez, Elizabeth A. Reap, Gary E. Archer, Stephen T. Keir, Roger E. McLendon, James E. Herndon, Patrick N. Healy, Xiuyu Cui, Scott E. Szafranski, Robert J. Schmittling, David J. Snyder, Carter M. Suryadevara, Chien-Tsun Kuan, Bryan D. Choi, Satish K. Chitneni, Teilo H. Schaller, Patrick C. Gedeon
Table S2 - Glioma cell lines and patient derived tumor samples used for study with the number of EGFRvIII receptors per cell, the number of EGFRwt receptors per cell and the proportion of cells expressing EGFRvIII in the given cell line or tumor samp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044ccc0bbab6f20d0b58d82dddba22dd
https://doi.org/10.1158/1078-0432.22464450.v1
https://doi.org/10.1158/1078-0432.22464450.v1
Autor:
John H. Sampson, Darell D. Bigner, Luis Sanchez-Perez, Elizabeth A. Reap, Gary E. Archer, Stephen T. Keir, Roger E. McLendon, James E. Herndon, Patrick N. Healy, Xiuyu Cui, Scott E. Szafranski, Robert J. Schmittling, David J. Snyder, Carter M. Suryadevara, Chien-Tsun Kuan, Bryan D. Choi, Satish K. Chitneni, Teilo H. Schaller, Patrick C. Gedeon
Purpose: Conventional therapy for malignant glioma fails to specifically target tumor cells. In contrast, substantial evidence indicates that if appropriately redirected, T cells can precisely eradicate tumors. Here we report the rational development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c540ead1b7766f857bb8730e93a593d
https://doi.org/10.1158/1078-0432.c.6525723.v1
https://doi.org/10.1158/1078-0432.c.6525723.v1
Autor:
John H. Sampson, Duane A. Mitchell, Peter E. Fecci, Darell D. Bigner, Henry S. Friedman, Allan H. Friedman, Roger E. McLendon, Gordana Vlahovic, Annick Desjardins, Kent J. Weinhold, Taylor M. Broome, Anastasie M. Dunn-Pirio, Smita K. Nair, Anirudh Saraswathula, Mohammed K. Hossain-Ibrahim, John S. Yi, Katherine A. Riccione, Adam M. Swartz, Olivia C. Campbell, Patrick C. Gedeon, Kendra L. Congdon, Patrick Healy, James E. Herndon, Pamela K. Norberg, Robert J. Schmittling, Gary E. Archer, Luis Sanchez-Perez, Kristen A. Batich, Carter M. Suryadevara, Elizabeth A. Reap
Median survival for glioblastoma (GBM) remains ex vivo analyses from this study found no change in the capacity of CMV pp65-specific T cells to gain multiple effector functions or polyfunctionality, which has been associated with superior antitumor e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ff9c63b4ce53b8abc0e4e7bd97521a
https://doi.org/10.1158/0008-5472.c.6509943.v1
https://doi.org/10.1158/0008-5472.c.6509943.v1
Autor:
Luis A Sanchez-Perez, Bryan D Choi, Gary E Archer, Xiuyu Cui, Catherine Flores, Laura A Johnson, Robert J Schmittling, David Snyder, James E Herndon, Darell D Bigner, Duane A Mitchell, John H Sampson
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59082 (2013)
Temozolomide (TMZ) is an alkylating agent shown to prolong survival in patients with high grade glioma and is routinely used to treat melanoma brain metastases. A prominent side effect of TMZ is induction of profound lymphopenia, which some suggest m
Externí odkaz:
https://doaj.org/article/35e9b35443d2484fa4d782fdea9099f5
Autor:
John H Sampson, Robert J Schmittling, Gary E Archer, Kendra L Congdon, Smita K Nair, Elizabeth A Reap, Annick Desjardins, Allan H Friedman, Henry S Friedman, James E Herndon, April Coan, Roger E McLendon, David A Reardon, James J Vredenburgh, Darell D Bigner, Duane A Mitchell
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31046 (2012)
Preclinical studies in mice have demonstrated that the prophylactic depletion of immunosuppressive regulatory T-cells (T(Regs)) through targeting the high affinity interleukin-2 (IL-2) receptor (IL-2Rα/CD25) can enhance anti-tumor immunotherapy. How
Externí odkaz:
https://doaj.org/article/9c5a1bf348704ed5af50908203b99a21
Autor:
Elizabeth A. Reap, Robert J. Schmittling, Pamela Norberg, Sylvia Janetzki, Adam M. Swartz, John H. Sampson, Luis Sanchez-Perez
Publikováno v:
Journal of Immunological Methods. 459:90-93
The ELISpot assay prevails as one of the most sensitive and meaningful assays for the detection of antigen-specific, effector immune responses. Acquisition of cellular analyte for ELISpot analysis is typically not problematic when derived from tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ba656f43f84b78d23319543d9d4800
https://doi.org/10.1016/j.jim.2018.05.015
https://doi.org/10.1016/j.jim.2018.05.015
Autor:
Olivia C. Campbell, Pamela Norberg, Gordana Vlahovic, Kendra L. Congdon, Kent J. Weinhold, Elizabeth A. Reap, Katherine A. Riccione, Adam M. Swartz, James E. Herndon, Anirudh Saraswathula, Duane Mitchell, Allan H. Friedman, Darell D. Bigner, Patrick Healy, Roger E. McLendon, John H. Sampson, Henry S. Friedman, Luis Sanchez-Perez, Peter E. Fecci, John S. Yi, Smita K. Nair, Patrick C. Gedeon, Mohammed K. Hossain-Ibrahim, Carter M. Suryadevara, Taylor M. Broome, Gary E. Archer, Annick Desjardins, Robert J. Schmittling, Anastasie Dunn-Pirio, Kristen A. Batich
Publikováno v:
Cancer Research. 78:256-264
Median survival for glioblastoma (GBM) remains Significance: A randomized pilot trial in patients with GBM implicates polyfunctional T-cell responses as a biomarker for effective antitumor immunotherapy. Cancer Res; 78(1); 256–64. ©2017 AACR.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d26c35c2e1832b480f32a01d76b195
https://doi.org/10.1158/0008-5472.can-17-0469
https://doi.org/10.1158/0008-5472.can-17-0469