Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Robert J. Perchalski"'
Publisher Summary This chapter reviews chromatographic separation of stable isotope-labeled (SIL) drugs for pharmacological studies. The mass spectrometer traditionally fulfils the role of a highly selective and sensitive detector placed at the tail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcd934134b8303068e475ba6891e4c99
https://doi.org/10.1016/s0165-7208(97)80154-7
https://doi.org/10.1016/s0165-7208(97)80154-7
Publikováno v:
Journal of chromatography. 535(1-2)
The use of stable isotope-labeled tracer compounds is the safest and most effective method to perform many steady state pharmacokinetic and drug interaction studies. We describe a method by which the heavily deuterated 2H10 analogues of carbamazepine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b010f024a07d8cf856e8561d1e95d3c
https://pubmed.ncbi.nlm.nih.gov/2089056
https://pubmed.ncbi.nlm.nih.gov/2089056
Autor:
D Vazquez, A Guterman, Robert J. Perchalski, T V Briggle, D Q McManus, R E Ramsay, P Wong, Richard A. Yost
Publikováno v:
Therapeutic drug monitoring. 12(3)
Free and total carbamazepine (CBZ) and carbamazepine-epoxide (CBZ-EP) plasma levels were obtained on 113 patients with epilepsy (18-61 years old) controlled on either monotherapy or coadministration with either phenobarbital (PB), phenytoin (PHT), va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96139d40c18bea411b0fc736c289d08
https://pubmed.ncbi.nlm.nih.gov/2112276
https://pubmed.ncbi.nlm.nih.gov/2112276
Publikováno v:
Analytical Chemistry. 54:1466-1471
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f297abcf608d8c32732c3f435e987c15
https://doi.org/10.1021/ac00246a006
https://doi.org/10.1021/ac00246a006
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 163:187-193
A high-performance liquid chromatographic method is described for monitoring plasma concentrations of cinromide (3-bromo-N-ethylcinnamamide) and its de-ethylated metabolite. Carbamazepine levels can be easily measured by the same technique. The N-iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::791e91eb37fdef7e5fa9ef615b467a18
https://doi.org/10.1016/s0378-4347(00)81462-0
https://doi.org/10.1016/s0378-4347(00)81462-0
Publikováno v:
Neuroscience Letters. 87:277-282
Many drugs can be selectively delivered to the brain by using a dihydropyridine in equilibrium pyridinium salt chemical delivery system (CDS). The interaction of these systems with central dopaminergic function was examined in this communication. Cas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e31d3270308320ebddd495503a2c431
https://doi.org/10.1016/0304-3940(88)90461-2
https://doi.org/10.1016/0304-3940(88)90461-2
Autor:
B. J. Wilder, Robert J. Perchalski
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 145:97-103
A previously published procedure for the gas chromatographic analysis of carbamazepine has been modified and expanded to allow simultaneous determination of phenylethylmalonamide, a metabolite of primidone. Internal standards that closely resemble ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::322bac2b57f67bdabed5283501544a6a
https://doi.org/10.1016/s0378-4347(00)81671-0
https://doi.org/10.1016/s0378-4347(00)81671-0
Publikováno v:
American Journal of Health-System Pharmacy. 38:1757-1760
Clearance of ethosuximide by hemodialysis was studied. Four patients with chronic renal disease supported by hemodialysis were given ethosuximide 500 mg four hours before dialysis. Samples of arterial and venous blood and dialysate were collected bef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25075f36f1f3f68375676f4ea2ced7b4
https://doi.org/10.1093/ajhp/38.11.1757
https://doi.org/10.1093/ajhp/38.11.1757
Publikováno v:
Analytical Chemistry. 47:1993-1999
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c0bd0bb077aab2bd250ecbac0529d2
https://doi.org/10.1021/ac60362a056
https://doi.org/10.1021/ac60362a056
Publikováno v:
Analytical Chemistry. 55:2002-2005
Description de l'interface laser a colorant pulse-spectrometre de masse quadripolaire triple. Application a l'analyse moleculaire multicomposant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56849ff48572e3becc5e9278fe0c89e5
https://doi.org/10.1021/ac00262a043
https://doi.org/10.1021/ac00262a043